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Development and validation of an interpretable prediction model using spatial patterns of tumor-infiltrating lymphocytes in H&E-stained whole-slide images for immune subtyping of lung adenocarcinoma.

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Title: Development and validation of an interpretable prediction model using spatial patterns of tumor-infiltrating lymphocytes in H&E-stained whole-slide images for immune subtyping of lung adenocarcinoma.
Authors: Li X; Department of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China., Qin HZ; Department of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China., Wei JY; Department of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China., Wei KL; Department of Pathology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China., Huang ZQ; Department of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Source: Frontiers in immunology [Front Immunol] 2026 May 08; Vol. 17, pp. 1773927. Date of Electronic Publication: 2026 May 08 (Print Publication: 2026).
Publication Type: Journal Article; Validation Study
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Department of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Qin+HZ%22">Qin HZ</searchLink>; Department of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Wei+JY%22">Wei JY</searchLink>; Department of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Wei+KL%22">Wei KL</searchLink>; Department of Pathology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Huang+ZQ%22">Huang ZQ</searchLink>; Department of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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        Value: 10.3389/fimmu.2026.1773927
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      – TitleFull: Development and validation of an interpretable prediction model using spatial patterns of tumor-infiltrating lymphocytes in H&E-stained whole-slide images for immune subtyping of lung adenocarcinoma.
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              Text: 2026 May 08
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