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A pivotal Wnt antagonist role promoting digit joint specification by constraining Wnt activity.

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Title: A pivotal Wnt antagonist role promoting digit joint specification by constraining Wnt activity.
Authors: Huang BL; Cancer & Developmental Biology Laboratory, CCR, National Cancer Institute, Frederick, MD, USA., Davis S; Genetics Branch, CCR, National Cancer Institute, Bethesda, MD, USA.; Univ. Colorado-Anschutz Medical Campus, Denver, CO, USA., Koyama E; Translational Research Program in Pediatric Orthopaedics,Division of Orthopaedic Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Pacifici M; Translational Research Program in Pediatric Orthopaedics,Division of Orthopaedic Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Mackem S; Cancer & Developmental Biology Laboratory, CCR, National Cancer Institute, Frederick, MD, USA. mackems@mail.nih.gov.
Source: Nature communications [Nat Commun] 2026 May 26. Date of Electronic Publication: 2026 May 26.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Huang+BL%22">Huang BL</searchLink>; Cancer & Developmental Biology Laboratory, CCR, National Cancer Institute, Frederick, MD, USA.<br /><searchLink fieldCode="AU" term="%22Davis+S%22">Davis S</searchLink>; Genetics Branch, CCR, National Cancer Institute, Bethesda, MD, USA.; Univ. Colorado-Anschutz Medical Campus, Denver, CO, USA.<br /><searchLink fieldCode="AU" term="%22Koyama+E%22">Koyama E</searchLink>; Translational Research Program in Pediatric Orthopaedics,Division of Orthopaedic Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Pacifici+M%22">Pacifici M</searchLink>; Translational Research Program in Pediatric Orthopaedics,Division of Orthopaedic Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Mackem+S%22">Mackem S</searchLink>; Cancer & Developmental Biology Laboratory, CCR, National Cancer Institute, Frederick, MD, USA. mackems@mail.nih.gov.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 May 26. <i>Date of Electronic Publication: </i>2026 May 26.
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        Value: 10.1038/s41467-026-73549-4
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              Text: 2026 May 26
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