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Host-microbial interactions at the nasal mucosa in young children and adults: A retrospective, cross-sectional study.

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Title: Host-microbial interactions at the nasal mucosa in young children and adults: A retrospective, cross-sectional study.
Authors: Reiné J; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Oxford Vaccine Group, University of Oxford, Oxford, UK. Electronic address: jesus.reine@paediatrics.ox.ac.uk., King LA; Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: l.a.king@lumc.nl., Singh Y; Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands., de Steenhuijsen Piters WAA; Department of Paediatric Immunology and Infectious Diseases, Wilhelmina Children's Hospital/University Medical Center Utrecht, Utrecht, the Netherlands; National Institute for Public Health and the Environment, Bilthoven, the Netherlands., Carniel BF; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK., Solórzano C; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Oxford Vaccine Group, University of Oxford, Oxford, UK., Mitsi E; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Oxford Vaccine Group, University of Oxford, Oxford, UK., Pojar S; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK., Nikolaou E; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Infection, Immunity and Global Health, Murdoch Children's Research Institute, Melbourne, VIC, Australia; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., German EL; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Department of Disease Control, London School of Hygiene and Tropical Medicine, London, UK., Blizard A; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK., Marcon F; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK., Marques AHC; Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands., Voskamp AL; Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands., Chu ML; Department of Paediatric Immunology and Infectious Diseases, Wilhelmina Children's Hospital/University Medical Center Utrecht, Utrecht, the Netherlands; National Institute for Public Health and the Environment, Bilthoven, the Netherlands., Hasrat R; Department of Paediatric Immunology and Infectious Diseases, Wilhelmina Children's Hospital/University Medical Center Utrecht, Utrecht, the Netherlands; National Institute for Public Health and the Environment, Bilthoven, the Netherlands., Hill H; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Hales C; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Brown L; Institute in the Park, Alder Hey Children's Hospital, Liverpool, UK., Horsley V; Institute in the Park, Alder Hey Children's Hospital, Liverpool, UK., Hughes LP; Institute in the Park, Alder Hey Children's Hospital, Liverpool, UK., Zaidi SR; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK., Connor V; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Morton B; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Collins AM; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Rylance J; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Lung Health Group, Malawi-Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi., Adler H; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK., Smits HH; Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands., Mahfouz A; Delft Bioinformatics Lab, Delft University of Technology, Delft, the Netherlands; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands., McNamara PS; Institute in the Park, Alder Hey Children's Hospital, Liverpool, UK., Nakaya HI; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paolo, Brazil; Hospital Israelita Albert Einstein, São Paulo, Brazil., Bogaert D; Department of Paediatric Immunology and Infectious Diseases, Wilhelmina Children's Hospital/University Medical Center Utrecht, Utrecht, the Netherlands; National Institute for Public Health and the Environment, Bilthoven, the Netherlands; Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK., Ferreira DM; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Oxford Vaccine Group, University of Oxford, Oxford, UK. Electronic address: daniela.ferreira@paediatrics.ox.ac.uk., Jochems SP; Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: s.p.jochems@lumc.nl.
Source: Cell reports [Cell Rep] 2026 May 21; Vol. 45 (5), pp. 117346. Date of Electronic Publication: 2026 May 21.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Host-microbial interactions at the nasal mucosa in young children and adults: A retrospective, cross-sectional study.
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  Data: <searchLink fieldCode="AU" term="%22Reiné+J%22">Reiné J</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Oxford Vaccine Group, University of Oxford, Oxford, UK. Electronic address: jesus.reine@paediatrics.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22King+LA%22">King LA</searchLink>; Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: l.a.king@lumc.nl.<br /><searchLink fieldCode="AU" term="%22Singh+Y%22">Singh Y</searchLink>; Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Steenhuijsen+Piters+WAA%22">de Steenhuijsen Piters WAA</searchLink>; Department of Paediatric Immunology and Infectious Diseases, Wilhelmina Children's Hospital/University Medical Center Utrecht, Utrecht, the Netherlands; National Institute for Public Health and the Environment, Bilthoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Carniel+BF%22">Carniel BF</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Solórzano+C%22">Solórzano C</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Oxford Vaccine Group, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Mitsi+E%22">Mitsi E</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Oxford Vaccine Group, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Pojar+S%22">Pojar S</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Nikolaou+E%22">Nikolaou E</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Infection, Immunity and Global Health, Murdoch Children's Research Institute, Melbourne, VIC, Australia; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22German+EL%22">German EL</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Department of Disease Control, London School of Hygiene and Tropical Medicine, London, UK.<br /><searchLink fieldCode="AU" term="%22Blizard+A%22">Blizard A</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Marcon+F%22">Marcon F</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Marques+AHC%22">Marques AHC</searchLink>; Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Voskamp+AL%22">Voskamp AL</searchLink>; Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Chu+ML%22">Chu ML</searchLink>; Department of Paediatric Immunology and Infectious Diseases, Wilhelmina Children's Hospital/University Medical Center Utrecht, Utrecht, the Netherlands; National Institute for Public Health and the Environment, Bilthoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Hasrat+R%22">Hasrat R</searchLink>; Department of Paediatric Immunology and Infectious Diseases, Wilhelmina Children's Hospital/University Medical Center Utrecht, Utrecht, the Netherlands; National Institute for Public Health and the Environment, Bilthoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Hill+H%22">Hill H</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Hales+C%22">Hales C</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Brown+L%22">Brown L</searchLink>; Institute in the Park, Alder Hey Children's Hospital, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Horsley+V%22">Horsley V</searchLink>; Institute in the Park, Alder Hey Children's Hospital, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Hughes+LP%22">Hughes LP</searchLink>; Institute in the Park, Alder Hey Children's Hospital, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Zaidi+SR%22">Zaidi SR</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Connor+V%22">Connor V</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Morton+B%22">Morton B</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Collins+AM%22">Collins AM</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Rylance+J%22">Rylance J</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Lung Health Group, Malawi-Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi.<br /><searchLink fieldCode="AU" term="%22Adler+H%22">Adler H</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Smits+HH%22">Smits HH</searchLink>; Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Mahfouz+A%22">Mahfouz A</searchLink>; Delft Bioinformatics Lab, Delft University of Technology, Delft, the Netherlands; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22McNamara+PS%22">McNamara PS</searchLink>; Institute in the Park, Alder Hey Children's Hospital, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Nakaya+HI%22">Nakaya HI</searchLink>; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paolo, Brazil; Hospital Israelita Albert Einstein, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Bogaert+D%22">Bogaert D</searchLink>; Department of Paediatric Immunology and Infectious Diseases, Wilhelmina Children's Hospital/University Medical Center Utrecht, Utrecht, the Netherlands; National Institute for Public Health and the Environment, Bilthoven, the Netherlands; Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Ferreira+DM%22">Ferreira DM</searchLink>; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Oxford Vaccine Group, University of Oxford, Oxford, UK. Electronic address: daniela.ferreira@paediatrics.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Jochems+SP%22">Jochems SP</searchLink>; Leiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: s.p.jochems@lumc.nl.
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  Data: <searchLink fieldCode="JN" term="%22101573691%22">Cell reports</searchLink> [Cell Rep] 2026 May 21; Vol. 45 (5), pp. 117346. <i>Date of Electronic Publication: </i>2026 May 21.
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