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The 2026 definition of ruxolitinib refractoriness in severe acute GVHD.

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Title: The 2026 definition of ruxolitinib refractoriness in severe acute GVHD.
Authors: Malard F; Centre de Recherche Saint-Antoine INSERM UMRs938, Service d'Hématologie Clinique et de Thérapie Cellulaire, Hôpital Saint Antoine, APHP, Sorbonne Université, Paris, France. florent.malard@inserm.fr., Chen YB; Hematopoietic Cell Transplant & Cell Therapy Program, Massachusetts General Brigham Cancer Institute, Boston, MA, USA., Al Malki MM; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA, USA., Perales MA; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Peric Z; Department of Hematology, University Hospital Centre Rijeka, Faculty of Medicine, University of Rijeka, Rijeka, Croatia., Ruggeri A; IRCCS San Raffaele Scientific Institute, Milano, Italy., Brissot E; Centre de Recherche Saint-Antoine INSERM UMRs938, Service d'Hématologie Clinique et de Thérapie Cellulaire, Hôpital Saint Antoine, APHP, Sorbonne Université, Paris, France., Sanz J; Hematology, University Hospital La Fe, Madrid, Spain., Duarte R; Department of Hematology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain., Morsink L; University Medical Center Groningen, Groningen, The Netherlands.; Rijksuniversiteit Groningen, Groningen, The Netherlands., Spyridonnidis A; University of Patras, Institute of Cell Therapy, Patras, Greece., Battipaglia G; Hematology Department, Federico II University of Naples, Naples, Italy., Nakamura R; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA, USA., Kharfan-Dabaja M; Division of Hematology-Oncology, Blood and Marrow Transplantation Program, Mayo Clinic, Jacksonville, FL, USA., Penak O; Charité - University Medicine Berlin, Berlin, Germany., Zeiser R; Department of Hematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, Freiburg University Medical Center, Freiburg im Breisgau, Germany., Mohty M; Centre de Recherche Saint-Antoine INSERM UMRs938, Service d'Hématologie Clinique et de Thérapie Cellulaire, Hôpital Saint Antoine, APHP, Sorbonne Université, Paris, France. mohamad.mohty@inserm.fr.
Source: Bone marrow transplantation [Bone Marrow Transplant] 2026 May 26. Date of Electronic Publication: 2026 May 26.
Publication Type: Letter
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8702459 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5365 (Electronic) Linking ISSN: 02683369 NLM ISO Abbreviation: Bone Marrow Transplant Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Malard+F%22">Malard F</searchLink>; Centre de Recherche Saint-Antoine INSERM UMRs938, Service d'Hématologie Clinique et de Thérapie Cellulaire, Hôpital Saint Antoine, APHP, Sorbonne Université, Paris, France. florent.malard@inserm.fr.<br /><searchLink fieldCode="AU" term="%22Chen+YB%22">Chen YB</searchLink>; Hematopoietic Cell Transplant & Cell Therapy Program, Massachusetts General Brigham Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Al+Malki+MM%22">Al Malki MM</searchLink>; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Perales+MA%22">Perales MA</searchLink>; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Peric+Z%22">Peric Z</searchLink>; Department of Hematology, University Hospital Centre Rijeka, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.<br /><searchLink fieldCode="AU" term="%22Ruggeri+A%22">Ruggeri A</searchLink>; IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Brissot+E%22">Brissot E</searchLink>; Centre de Recherche Saint-Antoine INSERM UMRs938, Service d'Hématologie Clinique et de Thérapie Cellulaire, Hôpital Saint Antoine, APHP, Sorbonne Université, Paris, France.<br /><searchLink fieldCode="AU" term="%22Sanz+J%22">Sanz J</searchLink>; Hematology, University Hospital La Fe, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Duarte+R%22">Duarte R</searchLink>; Department of Hematology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Morsink+L%22">Morsink L</searchLink>; University Medical Center Groningen, Groningen, The Netherlands.; Rijksuniversiteit Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Spyridonnidis+A%22">Spyridonnidis A</searchLink>; University of Patras, Institute of Cell Therapy, Patras, Greece.<br /><searchLink fieldCode="AU" term="%22Battipaglia+G%22">Battipaglia G</searchLink>; Hematology Department, Federico II University of Naples, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Nakamura+R%22">Nakamura R</searchLink>; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kharfan-Dabaja+M%22">Kharfan-Dabaja M</searchLink>; Division of Hematology-Oncology, Blood and Marrow Transplantation Program, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Penak+O%22">Penak O</searchLink>; Charité - University Medicine Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Zeiser+R%22">Zeiser R</searchLink>; Department of Hematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, Freiburg University Medical Center, Freiburg im Breisgau, Germany.<br /><searchLink fieldCode="AU" term="%22Mohty+M%22">Mohty M</searchLink>; Centre de Recherche Saint-Antoine INSERM UMRs938, Service d'Hématologie Clinique et de Thérapie Cellulaire, Hôpital Saint Antoine, APHP, Sorbonne Université, Paris, France. mohamad.mohty@inserm.fr.
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