Small extracellular vesicle signaling and mitochondrial transfer reprogram T helper cell function in human asthma.

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Title: Small extracellular vesicle signaling and mitochondrial transfer reprogram T helper cell function in human asthma.
Authors: Hough KP; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Trevor JL; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Ahmad S; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Wang Y; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Chacko BK; Mitochondrial Medicine Laboratory, Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA., Goliwas KF; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Strenkowski JG; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Liu Y; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Nowak JI; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.; Department of Histology, Medical University of Gdansk, Gdansk, Poland., Becker EJ Jr; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Kim YI; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.; Division of Global and Rural Health, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL, USA., Holmes R; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Bone NB; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Vang S; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Pritchard A; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Chin J; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Bodduluri S; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Antony VB; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Tousif S; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.; Department of Cellular Biology & Anatomy, LSUHS, LSU Health, Shreveport, LA, USA., Athar M; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA., Chanda D; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Mitra K; Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, USA.; Department of Biology, Ashoka University, National Capital Region-Delhi, India., Zmijewski JW; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Zhang J; Mitochondrial Medicine Laboratory, Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA., Duncan SR; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Thannickal VJ; Department of Medicine, Tulane University School of Medicine and the Southeast Louisiana Veterans Health Care System, New Orleans, LA, USA., Gabrielsson S; Division of Immunology and Respiratory Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.; Clinical Immunology and Transfusion Medicine and Center for Molecular Medicine, The Karolinska University Hospital, Stockholm, Sweden., Darley-Usmar VM; Mitochondrial Medicine Laboratory, Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA., Deshane JS; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA. treena@uab.edu.
Source: Nature communications [Nat Commun] 2026 May 26. Date of Electronic Publication: 2026 May 26.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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