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Efficacy and Safety of Telmisartan 20 mg/S-Amlodipine 2.5 mg versus Telmisartan 40 mg in Patients with Hypertension, Inadequately Controlled on Telmisartan 20 mg Monotherapy: A Randomized, Double-Blind, Multicenter, Phase 3 Trial.

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Title: Efficacy and Safety of Telmisartan 20 mg/S-Amlodipine 2.5 mg versus Telmisartan 40 mg in Patients with Hypertension, Inadequately Controlled on Telmisartan 20 mg Monotherapy: A Randomized, Double-Blind, Multicenter, Phase 3 Trial.
Authors: Youn JC; Division of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, Catholic Research Institute for Intractable Cardiovascular Disease, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Kim ES; Division of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, Catholic Research Institute for Intractable Cardiovascular Disease, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Park TH; Department of Cardiology, Dong-A University Hospital, Busan, Republic of Korea., Lee YS; Division of Cardiology, Department of Internal Medicine, Daegu Catholic University, Daegu, Republic of Korea., Hong SJ; Department of Cardiology, Cardiovascular Center, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Republic of Korea., Hwang JY; Division of Cardiology, Department of Internal Medicine, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, Republic of Korea., Han JK; Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea., Son JW; Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea., Lee CJ; Division of Cardiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Choi JH; Division of Cardiology, Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine and Biomedical Research Institute, Busan, Republic of Korea., Kwon SU; Department of Cardiology, Inje University College of Medicine, Ilsan-Paik Hospital, Goyang, Republic of Korea., Kim SY; Division of Cardiology, Department of Internal Medicine, Seoul Medical Center, Seoul, Republic of Korea., Park HC; Division of Cardiology, Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Republic of Korea., Choi SH; Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Source: Drug design, development and therapy [Drug Des Devel Ther] 2026 May 20; Vol. 20, pp. 587488. Date of Electronic Publication: 2026 May 20 (Print Publication: 2026).
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III; Comparative Study
Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE
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  Data: Efficacy and Safety of Telmisartan 20 mg/S-Amlodipine 2.5 mg versus Telmisartan 40 mg in Patients with Hypertension, Inadequately Controlled on Telmisartan 20 mg Monotherapy: A Randomized, Double-Blind, Multicenter, Phase 3 Trial.
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  Data: <searchLink fieldCode="AU" term="%22Youn+JC%22">Youn JC</searchLink>; Division of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, Catholic Research Institute for Intractable Cardiovascular Disease, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+ES%22">Kim ES</searchLink>; Division of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, Catholic Research Institute for Intractable Cardiovascular Disease, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+TH%22">Park TH</searchLink>; Department of Cardiology, Dong-A University Hospital, Busan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+YS%22">Lee YS</searchLink>; Division of Cardiology, Department of Internal Medicine, Daegu Catholic University, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Hong+SJ%22">Hong SJ</searchLink>; Department of Cardiology, Cardiovascular Center, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Hwang+JY%22">Hwang JY</searchLink>; Division of Cardiology, Department of Internal Medicine, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Han+JK%22">Han JK</searchLink>; Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Son+JW%22">Son JW</searchLink>; Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+CJ%22">Lee CJ</searchLink>; Division of Cardiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+JH%22">Choi JH</searchLink>; Division of Cardiology, Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine and Biomedical Research Institute, Busan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+SU%22">Kwon SU</searchLink>; Department of Cardiology, Inje University College of Medicine, Ilsan-Paik Hospital, Goyang, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SY%22">Kim SY</searchLink>; Division of Cardiology, Department of Internal Medicine, Seoul Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+HC%22">Park HC</searchLink>; Division of Cardiology, Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+SH%22">Choi SH</searchLink>; Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
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