A Real-World Controlled Multicentre Study Evaluating the Association Between Benralizumab Therapy and Major Outcomes in Severe Asthma.

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Title: A Real-World Controlled Multicentre Study Evaluating the Association Between Benralizumab Therapy and Major Outcomes in Severe Asthma.
Authors: Thomas D; College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.; Centre of Excellence in Treatable Traits, Hunter Medical Research Institute, Asthma and Breathing Programme, Newcastle, New South Wales, Australia., McDonald VM; College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.; Centre of Excellence in Treatable Traits, Hunter Medical Research Institute, Asthma and Breathing Programme, Newcastle, New South Wales, Australia.; Department of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, New South Wales, Australia., Thomas G; College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia., Lee J; Department of Respiratory and Sleep Medicine, Austin Health, Melbourne, Victoria, Australia., Chung LP; Department of Respiratory Medicine, Fiona Stanley Hospital, Murdoch, Western Australia, Australia., Peters M; Department of Thoracic Medicine, Concord Hospital, Concord, Australia.; Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales, Australia., Shukla SD; Graduate School of Health, University of Technology Sydney, Sydney, New South Wales, Australia., Hamada Y; College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.; Centre of Excellence in Treatable Traits, Hunter Medical Research Institute, Asthma and Breathing Programme, Newcastle, New South Wales, Australia.; Clinical Research Centre for Allergy and Rheumatology, NHO Sagamihara National Hospital, Sagamihara, Japan., Harvey ES; College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.; Centre of Excellence in Treatable Traits, Hunter Medical Research Institute, Asthma and Breathing Programme, Newcastle, New South Wales, Australia.; Department of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, New South Wales, Australia., Fricker M; College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.; Centre of Excellence in Treatable Traits, Hunter Medical Research Institute, Asthma and Breathing Programme, Newcastle, New South Wales, Australia., See H; School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia.; The Thoracic Society of Australia and New Zealand, Sydney, New South Wales, Australia., Sabin Thomas R; College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.; Centre of Excellence in Treatable Traits, Hunter Medical Research Institute, Asthma and Breathing Programme, Newcastle, New South Wales, Australia., Farah CS; Department of Thoracic Medicine, Concord Hospital, Concord, Australia.; Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Gillman A; Allergy, Asthma and Clinical Immunology, Alfred Health, Melbourne, Victoria, Australia., Katelaris CH; School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia.; Immunology and Allergy Unit, Campbelltown Hospital, Campbelltown, New South Wales, Australia., Katsoulotos GP; Woolcock Institute of Medical Research, University of Sydney, Glebe, New South Wales, Australia.; The University of Notre Dame, Sydney, Western Australia, Australia.; St George Specialist Centre, Kogarah, New South Wales, Australia.; St Vincent's Clinic, Darlinghurst, New South Wales, Australia., Langton D; Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.; Department of Thoracic Medicine, Frankston Hospital, Frankston, Victoria, Australia., Middleton PG; Department of Respiratory and Sleep Medicine, Westmead Hospital, Sydney, New South Wales, Australia.; Ludwig Engel Centre for Respiratory Research, The Westmead Institute of Medical Research, Sydney, New South Wales, Australia.; Westmead Clinical School, University of Sydney, Sydney, New South Wales, Australia., Reynolds P; Lung Research, University of Adelaide and Department of Thoracic Medicine, Royal Adelaide Hospital, Adelaide, Australia., Rimmer J; Rhinology and Skull Base Research Group, Applied Medical Research Centre, University of New South Wales, Sydney, Australia.; Faculty of Medicine, Notre Dame University, Sydney, Australia., Thien F; Eastern Health and Monash University, Melbourne, Victoria, Australia., Vincent S; Thoracic and Sleep Medicine, Cairns and Hinterland Hospital and Health Service, Cairns, Queensland, Australia., Upham JW; Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia., Gibson PG; College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.; Centre of Excellence in Treatable Traits, Hunter Medical Research Institute, Asthma and Breathing Programme, Newcastle, New South Wales, Australia.; Department of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, New South Wales, Australia.
Source: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2026 May 27. Date of Electronic Publication: 2026 May 27.
Publication Type: Journal Article
Journal Info: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 8906443 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2222 (Electronic) Linking ISSN: 09547894 NLM ISO Abbreviation: Clin Exp Allergy Subsets: MEDLINE
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  Data: A Real-World Controlled Multicentre Study Evaluating the Association Between Benralizumab Therapy and Major Outcomes in Severe Asthma.
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  Data: <searchLink fieldCode="AU" term="%22Thomas+D%22">Thomas D</searchLink>; College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.; Centre of Excellence in Treatable Traits, Hunter Medical Research Institute, Asthma and Breathing Programme, Newcastle, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22McDonald+VM%22">McDonald VM</searchLink>; College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.; Centre of Excellence in Treatable Traits, Hunter Medical Research Institute, Asthma and Breathing Programme, Newcastle, New South Wales, Australia.; Department of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Thomas+G%22">Thomas G</searchLink>; College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Department of Respiratory and Sleep Medicine, Austin Health, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Chung+LP%22">Chung LP</searchLink>; Department of Respiratory Medicine, Fiona Stanley Hospital, Murdoch, Western Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Peters+M%22">Peters M</searchLink>; Department of Thoracic Medicine, Concord Hospital, Concord, Australia.; Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Shukla+SD%22">Shukla SD</searchLink>; Graduate School of Health, University of Technology Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Hamada+Y%22">Hamada Y</searchLink>; College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.; Centre of Excellence in Treatable Traits, Hunter Medical Research Institute, Asthma and Breathing Programme, Newcastle, New South Wales, Australia.; Clinical Research Centre for Allergy and Rheumatology, NHO Sagamihara National Hospital, Sagamihara, Japan.<br /><searchLink fieldCode="AU" term="%22Harvey+ES%22">Harvey ES</searchLink>; College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.; Centre of Excellence in Treatable Traits, Hunter Medical Research Institute, Asthma and Breathing Programme, Newcastle, New South Wales, Australia.; Department of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Fricker+M%22">Fricker M</searchLink>; College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.; Centre of Excellence in Treatable Traits, Hunter Medical Research Institute, Asthma and Breathing Programme, Newcastle, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22See+H%22">See H</searchLink>; School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia.; The Thoracic Society of Australia and New Zealand, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Sabin+Thomas+R%22">Sabin Thomas R</searchLink>; College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.; Centre of Excellence in Treatable Traits, Hunter Medical Research Institute, Asthma and Breathing Programme, Newcastle, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Farah+CS%22">Farah CS</searchLink>; Department of Thoracic Medicine, Concord Hospital, Concord, Australia.; Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Gillman+A%22">Gillman A</searchLink>; Allergy, Asthma and Clinical Immunology, Alfred Health, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Katelaris+CH%22">Katelaris CH</searchLink>; School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia.; Immunology and Allergy Unit, Campbelltown Hospital, Campbelltown, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Katsoulotos+GP%22">Katsoulotos GP</searchLink>; Woolcock Institute of Medical Research, University of Sydney, Glebe, New South Wales, Australia.; The University of Notre Dame, Sydney, Western Australia, Australia.; St George Specialist Centre, Kogarah, New South Wales, Australia.; St Vincent's Clinic, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Langton+D%22">Langton D</searchLink>; Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.; Department of Thoracic Medicine, Frankston Hospital, Frankston, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Middleton+PG%22">Middleton PG</searchLink>; Department of Respiratory and Sleep Medicine, Westmead Hospital, Sydney, New South Wales, Australia.; Ludwig Engel Centre for Respiratory Research, The Westmead Institute of Medical Research, Sydney, New South Wales, Australia.; Westmead Clinical School, University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Reynolds+P%22">Reynolds P</searchLink>; Lung Research, University of Adelaide and Department of Thoracic Medicine, Royal Adelaide Hospital, Adelaide, Australia.<br /><searchLink fieldCode="AU" term="%22Rimmer+J%22">Rimmer J</searchLink>; Rhinology and Skull Base Research Group, Applied Medical Research Centre, University of New South Wales, Sydney, Australia.; Faculty of Medicine, Notre Dame University, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Thien+F%22">Thien F</searchLink>; Eastern Health and Monash University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Vincent+S%22">Vincent S</searchLink>; Thoracic and Sleep Medicine, Cairns and Hinterland Hospital and Health Service, Cairns, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Upham+JW%22">Upham JW</searchLink>; Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Gibson+PG%22">Gibson PG</searchLink>; College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.; Centre of Excellence in Treatable Traits, Hunter Medical Research Institute, Asthma and Breathing Programme, Newcastle, New South Wales, Australia.; Department of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, New South Wales, Australia.
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