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Deciphering cytokine-driven ADP-ribosylation signaling networks via Af1521-based mass spectrometry analysis of labile Glu/Asp-linkages.

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Title: Deciphering cytokine-driven ADP-ribosylation signaling networks via Af1521-based mass spectrometry analysis of labile Glu/Asp-linkages.
Authors: Buch-Larsen SC; Proteomics program, Novo Nordisk Foundation Center for Protein Research, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. sara.larsen@cpr.ku.dk.; Copenhagen Center for Glycocalyx Research, Department of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark. sara.larsen@cpr.ku.dk., Hendriks IA; Proteomics program, Novo Nordisk Foundation Center for Protein Research, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. ivo.hendriks@cpr.ku.dk.; Copenhagen Center for Glycocalyx Research, Department of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark. ivo.hendriks@cpr.ku.dk., Tashiro K; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA., Elsborg JD; Proteomics program, Novo Nordisk Foundation Center for Protein Research, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Vakhrushev SY; Copenhagen Center for Glycocalyx Research, Department of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark., Olsen JV; Proteomics program, Novo Nordisk Foundation Center for Protein Research, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Copenhagen Center for Glycocalyx Research, Department of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark., Lüscher B; Institute of Biochemistry and Molecular Biology, RWTH Aachen University, Aachen, Germany., Liszczak G; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA., Ahel I; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Nielsen ML; Proteomics program, Novo Nordisk Foundation Center for Protein Research, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
Source: Nature communications [Nat Commun] 2026 May 27. Date of Electronic Publication: 2026 May 27.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Buch-Larsen+SC%22">Buch-Larsen SC</searchLink>; Proteomics program, Novo Nordisk Foundation Center for Protein Research, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. sara.larsen@cpr.ku.dk.; Copenhagen Center for Glycocalyx Research, Department of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark. sara.larsen@cpr.ku.dk.<br /><searchLink fieldCode="AU" term="%22Hendriks+IA%22">Hendriks IA</searchLink>; Proteomics program, Novo Nordisk Foundation Center for Protein Research, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. ivo.hendriks@cpr.ku.dk.; Copenhagen Center for Glycocalyx Research, Department of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark. ivo.hendriks@cpr.ku.dk.<br /><searchLink fieldCode="AU" term="%22Tashiro+K%22">Tashiro K</searchLink>; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Elsborg+JD%22">Elsborg JD</searchLink>; Proteomics program, Novo Nordisk Foundation Center for Protein Research, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Vakhrushev+SY%22">Vakhrushev SY</searchLink>; Copenhagen Center for Glycocalyx Research, Department of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Olsen+JV%22">Olsen JV</searchLink>; Proteomics program, Novo Nordisk Foundation Center for Protein Research, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Copenhagen Center for Glycocalyx Research, Department of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Lüscher+B%22">Lüscher B</searchLink>; Institute of Biochemistry and Molecular Biology, RWTH Aachen University, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Liszczak+G%22">Liszczak G</searchLink>; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Ahel+I%22">Ahel I</searchLink>; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Nielsen+ML%22">Nielsen ML</searchLink>; Proteomics program, Novo Nordisk Foundation Center for Protein Research, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
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