Real-time search-assisted multiplexed quantitative proteomics reveals system-wide cryptic translation initiation in human cancer cells.

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Title: Real-time search-assisted multiplexed quantitative proteomics reveals system-wide cryptic translation initiation in human cancer cells.
Authors: Kozuka-Hata H; Medical Proteomics Laboratory, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-Ku, Tokyo, 108-8639, Japan., Hiroki T; Medical Proteomics Laboratory, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-Ku, Tokyo, 108-8639, Japan., Kitamura A; Medical Proteomics Laboratory, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-Ku, Tokyo, 108-8639, Japan., Miyamura N; Medical Proteomics Laboratory, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-Ku, Tokyo, 108-8639, Japan., Akiyama T; Laboratory of Molecular and Genetic Information, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-Ku, Tokyo, 113-0032, Japan., Inoue JI; The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), 4-6-1, Shirokanedai, Minato-Ku, Tokyo, 108-8639, Japan., Tsumoto K; Medical Proteomics Laboratory, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-Ku, Tokyo, 108-8639, Japan.; Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8656, Japan., Oyama M; Medical Proteomics Laboratory, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-Ku, Tokyo, 108-8639, Japan. moyama@ims.u-tokyo.ac.jp.
Source: Genome biology [Genome Biol] 2026 May 28. Date of Electronic Publication: 2026 May 28.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE
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  Data: Real-time search-assisted multiplexed quantitative proteomics reveals system-wide cryptic translation initiation in human cancer cells.
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  Data: <searchLink fieldCode="AU" term="%22Kozuka-Hata+H%22">Kozuka-Hata H</searchLink>; Medical Proteomics Laboratory, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-Ku, Tokyo, 108-8639, Japan.<br /><searchLink fieldCode="AU" term="%22Hiroki+T%22">Hiroki T</searchLink>; Medical Proteomics Laboratory, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-Ku, Tokyo, 108-8639, Japan.<br /><searchLink fieldCode="AU" term="%22Kitamura+A%22">Kitamura A</searchLink>; Medical Proteomics Laboratory, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-Ku, Tokyo, 108-8639, Japan.<br /><searchLink fieldCode="AU" term="%22Miyamura+N%22">Miyamura N</searchLink>; Medical Proteomics Laboratory, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-Ku, Tokyo, 108-8639, Japan.<br /><searchLink fieldCode="AU" term="%22Akiyama+T%22">Akiyama T</searchLink>; Laboratory of Molecular and Genetic Information, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-Ku, Tokyo, 113-0032, Japan.<br /><searchLink fieldCode="AU" term="%22Inoue+JI%22">Inoue JI</searchLink>; The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), 4-6-1, Shirokanedai, Minato-Ku, Tokyo, 108-8639, Japan.<br /><searchLink fieldCode="AU" term="%22Tsumoto+K%22">Tsumoto K</searchLink>; Medical Proteomics Laboratory, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-Ku, Tokyo, 108-8639, Japan.; Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8656, Japan.<br /><searchLink fieldCode="AU" term="%22Oyama+M%22">Oyama M</searchLink>; Medical Proteomics Laboratory, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-Ku, Tokyo, 108-8639, Japan. moyama@ims.u-tokyo.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%22100960660%22">Genome biology</searchLink> [Genome Biol] 2026 May 28. <i>Date of Electronic Publication: </i>2026 May 28.
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        Value: 10.1186/s13059-026-04120-z
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              Text: 2026 May 28
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