Maternal exposure to the thyroperoxidase-inhibiting pesticide amitrole induces hypothyroidism and developmental neurotoxicity in the rat brain.

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Title: Maternal exposure to the thyroperoxidase-inhibiting pesticide amitrole induces hypothyroidism and developmental neurotoxicity in the rat brain.
Authors: Ramhøj L; National Food Institute, Technical University of Denmark, Kgs. Lyngby, Denmark., Ardenkjær-Skinnerup J; National Food Institute, Technical University of Denmark, Kgs. Lyngby, Denmark., Davidsen N; National Food Institute, Technical University of Denmark, Kgs. Lyngby, Denmark., Ford J; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, United States., Kuehn C; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, United States., Frädrich C; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Institut für Experimentelle Endokrinologie, Berlin, Germany., Köhrle J; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Institut für Experimentelle Endokrinologie, Berlin, Germany., Gilbert M; Center for Public Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, United States., Svingen T; National Food Institute, Technical University of Denmark, Kgs. Lyngby, Denmark., Axelstad M; National Food Institute, Technical University of Denmark, Kgs. Lyngby, Denmark.
Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2026 May 12; Vol. 17, pp. 1823237. Date of Electronic Publication: 2026 May 12 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE
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  Data: Maternal exposure to the thyroperoxidase-inhibiting pesticide amitrole induces hypothyroidism and developmental neurotoxicity in the rat brain.
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  Data: <searchLink fieldCode="AU" term="%22Ramhøj+L%22">Ramhøj L</searchLink>; National Food Institute, Technical University of Denmark, Kgs. Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Ardenkjær-Skinnerup+J%22">Ardenkjær-Skinnerup J</searchLink>; National Food Institute, Technical University of Denmark, Kgs. Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Davidsen+N%22">Davidsen N</searchLink>; National Food Institute, Technical University of Denmark, Kgs. Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Ford+J%22">Ford J</searchLink>; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, United States.<br /><searchLink fieldCode="AU" term="%22Kuehn+C%22">Kuehn C</searchLink>; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, United States.<br /><searchLink fieldCode="AU" term="%22Frädrich+C%22">Frädrich C</searchLink>; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Institut für Experimentelle Endokrinologie, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Köhrle+J%22">Köhrle J</searchLink>; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Institut für Experimentelle Endokrinologie, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Gilbert+M%22">Gilbert M</searchLink>; Center for Public Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, United States.<br /><searchLink fieldCode="AU" term="%22Svingen+T%22">Svingen T</searchLink>; National Food Institute, Technical University of Denmark, Kgs. Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Axelstad+M%22">Axelstad M</searchLink>; National Food Institute, Technical University of Denmark, Kgs. Lyngby, Denmark.
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  Data: <searchLink fieldCode="JN" term="%22101555782%22">Frontiers in endocrinology</searchLink> [Front Endocrinol (Lausanne)] 2026 May 12; Vol. 17, pp. 1823237. <i>Date of Electronic Publication: </i>2026 May 12 (<i>Print Publication: </i>2026).
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              Text: 2026 May 12
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