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DPP3 deficiency impacts bone quality and sensitizes to metabolic alterations.

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Title: DPP3 deficiency impacts bone quality and sensitizes to metabolic alterations.
Authors: Bevacqua E; Humanitas Research Hospital IRCCS, Bone Metabolism Unit, Laboratory of Translational Endocrinology and Metabolism, Rozzano, Italy., Granata V; Humanitas Research Hospital IRCCS, Cellular and Humoral Innate Immunity Lab, Rozzano, Italy., Panetta D; National Research Council-Institute of Clinical Physiology, Pisa, Italy., Longo E; Elettra-Sincrotrone Trieste SCpA, Italy., Prašek M; Elettra-Sincrotrone Trieste SCpA, Italy., Sanchez PJ; Elettra-Sincrotrone Trieste SCpA, Italy., Violi F; Humanitas Research Hospital IRCCS, Cellular and Humoral Innate Immunity Lab, Rozzano, Italy., Giacchi L; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Bertola L; Department of Veterinary Medicine and Animal Sciences, University of Milan, Lodi, Italy; Mouse & Animal Pathology Laboratory (MAPLab), Fondazione UniMi, Milan, Italy., Tromba G; Elettra-Sincrotrone Trieste SCpA, Italy., Santillo M; Department of Clinical Medicine and Surgery, University of Naples 'Federico II', Naples, Italy., Rucci N; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Recordati C; Department of Veterinary Medicine and Animal Sciences, University of Milan, Lodi, Italy; Mouse & Animal Pathology Laboratory (MAPLab), Fondazione UniMi, Milan, Italy., Mazziotti G; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele (MI), Italy; Metabolic Bone Diseases and Osteoporosis Section, Endocrinology, Diabetology and Andrology Unit, Humanitas Research Hospital IRCCS, Rozzano, Italy., Morenghi E; Biostatistics Unit, IRCCS Humanitas Research Hospital, Rozzano, Italy., Menale C; Department of Clinical Medicine and Surgery, University of Naples 'Federico II', Naples, Italy., Sobacchi C; Humanitas Research Hospital IRCCS, Bone Metabolism Unit, Laboratory of Translational Endocrinology and Metabolism, Rozzano, Italy; Milan Unit, National Research Council-Institute for Genetic and Biomedical Research (CNR-IRGB), Italy. Electronic address: cristina.sobacchi@humanitasresearch.it.
Source: Bone [Bone] 2026 Sep; Vol. 210, pp. 117951. Date of Electronic Publication: 2026 May 27.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8504048 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2763 (Electronic) Linking ISSN: 18732763 NLM ISO Abbreviation: Bone Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: DPP3 deficiency impacts bone quality and sensitizes to metabolic alterations.
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  Data: <searchLink fieldCode="AU" term="%22Bevacqua+E%22">Bevacqua E</searchLink>; Humanitas Research Hospital IRCCS, Bone Metabolism Unit, Laboratory of Translational Endocrinology and Metabolism, Rozzano, Italy.<br /><searchLink fieldCode="AU" term="%22Granata+V%22">Granata V</searchLink>; Humanitas Research Hospital IRCCS, Cellular and Humoral Innate Immunity Lab, Rozzano, Italy.<br /><searchLink fieldCode="AU" term="%22Panetta+D%22">Panetta D</searchLink>; National Research Council-Institute of Clinical Physiology, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Longo+E%22">Longo E</searchLink>; Elettra-Sincrotrone Trieste SCpA, Italy.<br /><searchLink fieldCode="AU" term="%22Prašek+M%22">Prašek M</searchLink>; Elettra-Sincrotrone Trieste SCpA, Italy.<br /><searchLink fieldCode="AU" term="%22Sanchez+PJ%22">Sanchez PJ</searchLink>; Elettra-Sincrotrone Trieste SCpA, Italy.<br /><searchLink fieldCode="AU" term="%22Violi+F%22">Violi F</searchLink>; Humanitas Research Hospital IRCCS, Cellular and Humoral Innate Immunity Lab, Rozzano, Italy.<br /><searchLink fieldCode="AU" term="%22Giacchi+L%22">Giacchi L</searchLink>; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Bertola+L%22">Bertola L</searchLink>; Department of Veterinary Medicine and Animal Sciences, University of Milan, Lodi, Italy; Mouse & Animal Pathology Laboratory (MAPLab), Fondazione UniMi, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Tromba+G%22">Tromba G</searchLink>; Elettra-Sincrotrone Trieste SCpA, Italy.<br /><searchLink fieldCode="AU" term="%22Santillo+M%22">Santillo M</searchLink>; Department of Clinical Medicine and Surgery, University of Naples 'Federico II', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Rucci+N%22">Rucci N</searchLink>; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Recordati+C%22">Recordati C</searchLink>; Department of Veterinary Medicine and Animal Sciences, University of Milan, Lodi, Italy; Mouse & Animal Pathology Laboratory (MAPLab), Fondazione UniMi, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mazziotti+G%22">Mazziotti G</searchLink>; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele (MI), Italy; Metabolic Bone Diseases and Osteoporosis Section, Endocrinology, Diabetology and Andrology Unit, Humanitas Research Hospital IRCCS, Rozzano, Italy.<br /><searchLink fieldCode="AU" term="%22Morenghi+E%22">Morenghi E</searchLink>; Biostatistics Unit, IRCCS Humanitas Research Hospital, Rozzano, Italy.<br /><searchLink fieldCode="AU" term="%22Menale+C%22">Menale C</searchLink>; Department of Clinical Medicine and Surgery, University of Naples 'Federico II', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Sobacchi+C%22">Sobacchi C</searchLink>; Humanitas Research Hospital IRCCS, Bone Metabolism Unit, Laboratory of Translational Endocrinology and Metabolism, Rozzano, Italy; Milan Unit, National Research Council-Institute for Genetic and Biomedical Research (CNR-IRGB), Italy. Electronic address: cristina.sobacchi@humanitasresearch.it.
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  Data: <searchLink fieldCode="JN" term="%228504048%22">Bone</searchLink> [Bone] 2026 Sep; Vol. 210, pp. 117951. <i>Date of Electronic Publication: </i>2026 May 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8504048 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-2763 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218732763%22">18732763 </searchLink><i>NLM ISO Abbreviation: </i>Bone <i>Subsets: </i>MEDLINE
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