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Deoxynivalenol Impairs Ovarian Function by Triggering Ferroptosis in Granulosa Cells through GPX2 Inhibition and Oxidative Stress.

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Title: Deoxynivalenol Impairs Ovarian Function by Triggering Ferroptosis in Granulosa Cells through GPX2 Inhibition and Oxidative Stress.
Authors: Zhou R; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China., Bu Y; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China., Guan JY; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China., Li JR; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China., Gao M; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China., Wu XD; Anhui Provincial Key Laboratory of Livestock and Poultry Product Safety Engineering, Institute of Animal Husbandry and Veterinary Medicine, Anhui Academy of Agricultural Sciences, Hefei 230001, China., Yin ZJ; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China., Zheng XR; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China., Zhang XD; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China., Yin HW; Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Livestock and Poultry Multi-Omics of MARA, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518120, China., Fan SH; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Source: Journal of agricultural and food chemistry [J Agric Food Chem] 2026 Jun 10; Vol. 74 (22), pp. 17405-17422. Date of Electronic Publication: 2026 May 29.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Deoxynivalenol Impairs Ovarian Function by Triggering Ferroptosis in Granulosa Cells through GPX2 Inhibition and Oxidative Stress.
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  Data: <searchLink fieldCode="AU" term="%22Zhou+R%22">Zhou R</searchLink>; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.<br /><searchLink fieldCode="AU" term="%22Bu+Y%22">Bu Y</searchLink>; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.<br /><searchLink fieldCode="AU" term="%22Guan+JY%22">Guan JY</searchLink>; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.<br /><searchLink fieldCode="AU" term="%22Li+JR%22">Li JR</searchLink>; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.<br /><searchLink fieldCode="AU" term="%22Gao+M%22">Gao M</searchLink>; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.<br /><searchLink fieldCode="AU" term="%22Wu+XD%22">Wu XD</searchLink>; Anhui Provincial Key Laboratory of Livestock and Poultry Product Safety Engineering, Institute of Animal Husbandry and Veterinary Medicine, Anhui Academy of Agricultural Sciences, Hefei 230001, China.<br /><searchLink fieldCode="AU" term="%22Yin+ZJ%22">Yin ZJ</searchLink>; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.<br /><searchLink fieldCode="AU" term="%22Zheng+XR%22">Zheng XR</searchLink>; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.<br /><searchLink fieldCode="AU" term="%22Zhang+XD%22">Zhang XD</searchLink>; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.<br /><searchLink fieldCode="AU" term="%22Yin+HW%22">Yin HW</searchLink>; Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Livestock and Poultry Multi-Omics of MARA, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518120, China.<br /><searchLink fieldCode="AU" term="%22Fan+SH%22">Fan SH</searchLink>; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
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  Data: <searchLink fieldCode="JN" term="%220374755%22">Journal of agricultural and food chemistry</searchLink> [J Agric Food Chem] 2026 Jun 10; Vol. 74 (22), pp. 17405-17422. <i>Date of Electronic Publication: </i>2026 May 29.
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        Value: 10.1021/acs.jafc.6c02013
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        Text: English
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      – TitleFull: Deoxynivalenol Impairs Ovarian Function by Triggering Ferroptosis in Granulosa Cells through GPX2 Inhibition and Oxidative Stress.
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              Text: 2026 Jun 10
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