Data-driven computational modeling of CAR-T cell function.

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Title: Data-driven computational modeling of CAR-T cell function.
Authors: Shah V; Department of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI, United States., Womack JA; Department of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI, United States., Palen K; Blood and Marrow Transplant Program (BMT) and Cellular Therapy Program, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, United States., Johnson BD; Blood and Marrow Transplant Program (BMT) and Cellular Therapy Program, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, United States., Hematti P; Blood and Marrow Transplant Program (BMT) and Cellular Therapy Program, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, United States., Kearl TJ; Blood and Marrow Transplant Program (BMT) and Cellular Therapy Program, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, United States., Shah NN; Blood and Marrow Transplant Program (BMT) and Cellular Therapy Program, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, United States., Terhune SS; Department of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI, United States.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, United States.; Department of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, United States., Dash RK; Department of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI, United States.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, United States.; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, United States.
Source: Frontiers in immunology [Front Immunol] 2026 May 13; Vol. 17, pp. 1707783. Date of Electronic Publication: 2026 May 13 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: Data-driven computational modeling of CAR-T cell function.
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  Data: <searchLink fieldCode="AU" term="%22Shah+V%22">Shah V</searchLink>; Department of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI, United States.<br /><searchLink fieldCode="AU" term="%22Womack+JA%22">Womack JA</searchLink>; Department of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI, United States.<br /><searchLink fieldCode="AU" term="%22Palen+K%22">Palen K</searchLink>; Blood and Marrow Transplant Program (BMT) and Cellular Therapy Program, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.<br /><searchLink fieldCode="AU" term="%22Johnson+BD%22">Johnson BD</searchLink>; Blood and Marrow Transplant Program (BMT) and Cellular Therapy Program, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, United States.<br /><searchLink fieldCode="AU" term="%22Hematti+P%22">Hematti P</searchLink>; Blood and Marrow Transplant Program (BMT) and Cellular Therapy Program, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, United States.<br /><searchLink fieldCode="AU" term="%22Kearl+TJ%22">Kearl TJ</searchLink>; Blood and Marrow Transplant Program (BMT) and Cellular Therapy Program, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, United States.<br /><searchLink fieldCode="AU" term="%22Shah+NN%22">Shah NN</searchLink>; Blood and Marrow Transplant Program (BMT) and Cellular Therapy Program, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, United States.<br /><searchLink fieldCode="AU" term="%22Terhune+SS%22">Terhune SS</searchLink>; Department of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI, United States.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, United States.; Department of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, United States.<br /><searchLink fieldCode="AU" term="%22Dash+RK%22">Dash RK</searchLink>; Department of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI, United States.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, United States.; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, United States.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 May 13; Vol. 17, pp. 1707783. <i>Date of Electronic Publication: </i>2026 May 13 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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        Value: 10.3389/fimmu.2026.1707783
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              Text: 2026 May 13
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