Multiscale predictive cellular modeling: integrating hypothesis grammars, digital twins, and multi-omics for In silico oncology and precision theranostics.

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Title: Multiscale predictive cellular modeling: integrating hypothesis grammars, digital twins, and multi-omics for In silico oncology and precision theranostics.
Authors: Gopukumar ST; Nanobioinformatics Unit, Department of General Surgery, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha Medical College and Hospital, Saveetha University, Chennai, Tamil Nadu, 602105, India., Dwivedi D; MAX Healthcare Institute Limited (Educational division MAX society of Medical Academics Innovation and Research), Academy of Scientific and Innovative Research, AcSIR-MSMAIR, Max Healthcare, Saket, New Delhi, 110017, India.; School of Biotechnology (SBT), Jawaharlal Nehru University (JNU), New Delhi, 110067, India., Rahamathulla M; Department of Pharmaceutics, College of Pharmacy, King Khalid University, Al Faraa, Abha, 62223, Saudi Arabia., Ahmed MM; Department of Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia., Soni TK; Department of Biosciences, JIS University, Kolkata, West Bengal, 700109, India., Natarajan PG; Department of Plastic, Reconstructive & Craniofacial Surgery, Saveetha Medical College & Hospital, Saveetha Institute of Medical & Technical Sciences (SIMATS), Chennai, Tamil Nadu, 602105, India., Ramkanth S; Department of Pharmaceutics, Karpagam College of Pharmacy, Coimbatore, Tamil Nadu, 641032, India., Mitra A; Department of Bioscience and Bioengineering, Indian Institute of Technology, IIT-B), Bombay, Mumbai, Maharashtra, 400076, India., Das U; School of Biotechnology (SBT), Jawaharlal Nehru University (JNU), New Delhi, 110067, India. uddalakdas@iisc.ac.in.; Developmental Biology and Genetics (DBG), Division of Biological Sciences, Indian Institute of Science (IISc), Bengaluru, 560012, India. uddalakdas@iisc.ac.in.
Source: Functional & integrative genomics [Funct Integr Genomics] 2026 May 29; Vol. 26 (1). Date of Electronic Publication: 2026 May 29.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 100939343 Publication Model: Electronic Cited Medium: Internet ISSN: 1438-7948 (Electronic) Linking ISSN: 1438793X NLM ISO Abbreviation: Funct Integr Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Multiscale predictive cellular modeling: integrating hypothesis grammars, digital twins, and multi-omics for In silico oncology and precision theranostics.
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  Data: <searchLink fieldCode="AU" term="%22Gopukumar+ST%22">Gopukumar ST</searchLink>; Nanobioinformatics Unit, Department of General Surgery, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha Medical College and Hospital, Saveetha University, Chennai, Tamil Nadu, 602105, India.<br /><searchLink fieldCode="AU" term="%22Dwivedi+D%22">Dwivedi D</searchLink>; MAX Healthcare Institute Limited (Educational division MAX society of Medical Academics Innovation and Research), Academy of Scientific and Innovative Research, AcSIR-MSMAIR, Max Healthcare, Saket, New Delhi, 110017, India.; School of Biotechnology (SBT), Jawaharlal Nehru University (JNU), New Delhi, 110067, India.<br /><searchLink fieldCode="AU" term="%22Rahamathulla+M%22">Rahamathulla M</searchLink>; Department of Pharmaceutics, College of Pharmacy, King Khalid University, Al Faraa, Abha, 62223, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Ahmed+MM%22">Ahmed MM</searchLink>; Department of Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Soni+TK%22">Soni TK</searchLink>; Department of Biosciences, JIS University, Kolkata, West Bengal, 700109, India.<br /><searchLink fieldCode="AU" term="%22Natarajan+PG%22">Natarajan PG</searchLink>; Department of Plastic, Reconstructive & Craniofacial Surgery, Saveetha Medical College & Hospital, Saveetha Institute of Medical & Technical Sciences (SIMATS), Chennai, Tamil Nadu, 602105, India.<br /><searchLink fieldCode="AU" term="%22Ramkanth+S%22">Ramkanth S</searchLink>; Department of Pharmaceutics, Karpagam College of Pharmacy, Coimbatore, Tamil Nadu, 641032, India.<br /><searchLink fieldCode="AU" term="%22Mitra+A%22">Mitra A</searchLink>; Department of Bioscience and Bioengineering, Indian Institute of Technology, IIT-B), Bombay, Mumbai, Maharashtra, 400076, India.<br /><searchLink fieldCode="AU" term="%22Das+U%22">Das U</searchLink>; School of Biotechnology (SBT), Jawaharlal Nehru University (JNU), New Delhi, 110067, India. uddalakdas@iisc.ac.in.; Developmental Biology and Genetics (DBG), Division of Biological Sciences, Indian Institute of Science (IISc), Bengaluru, 560012, India. uddalakdas@iisc.ac.in.
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  Data: <searchLink fieldCode="JN" term="%22100939343%22">Functional & integrative genomics</searchLink> [Funct Integr Genomics] 2026 May 29; Vol. 26 (1). <i>Date of Electronic Publication: </i>2026 May 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>100939343 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1438-7948 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221438793X%22">1438793X </searchLink><i>NLM ISO Abbreviation: </i>Funct Integr Genomics <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42213163
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        Value: 10.1007/s10142-026-01890-4
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              Text: 2026 May 29
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