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IL-16 production is a mechanism of resistance to BTK inhibitors and R-CHOP in lymphomas.

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Title: IL-16 production is a mechanism of resistance to BTK inhibitors and R-CHOP in lymphomas.
Authors: Arribas AJ; Università della Svizzera italiana, Institute of Oncology Research, Bellinzona, Switzerland., Cannas E; 1 Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland, Bellinzona, Switzerland., Sartori G; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland., Guidetti F; Università della Svizzera italiana, Istituto Oncologico di Ricerca., Cascione L; IOR - Institute of Oncology Research, Bellinzona, Switzerland., Napoli S; Institute of Oncology Research, Bellinzona, Switzerland., Forestieri G; Institute of Oncology Research, Bellinzona, Switzerland., Fuzio F; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland., Pesenti EDS; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland., Tarantelli C; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland., Spriano F; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, bellinzona, Switzerland., Zucchetto A; Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy., Rossi FM; Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy., Bruscaggin A; Institute of Oncology Research, Bellinzona, Switzerland., Rinaldi A; Institute of Oncology Research, Bellinzona, Switzerland., Castro de Moura M; Josep Carreras Leukaemia Research Institute, Badalona, Spain., Jovic S; Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland., Raimondi A; Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland., Bordone Pittau R; IOSI Oncology Institute of Southern Switzerland., Terzi di Bergamo L; Institute of Oncology Research, Bellinzona, Switzerland., Ye X; Karolinska Institutet, Stockholm, Sweden., Stathis A; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzoona, Switzerland., Ben-David Y; State Key Laboratory for Functions and Applications of Medicinal Plants, Guiyang, China., Pan-Hammarström Q; Karolinska Institutet, Stockholm, Sweden., Simonetta F; Geneva University Hospitals and University of Geneva, Genève, Switzerland., Stussi G; Oncology Institute of Southern Switzerland, Bellinzona, Switzerland., Zucca E; Institute of Oncology Research, Bellinzona, Switzerland., Gattei V; Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy., Brown JR; Dana-Farber Cancer Institute, Boston, Massachusetts, United States., Esteller M; Josep Carreras Leukaemia Research Institute (IJC), Badalona, Spain., Rossi D; Institute of Oncology Research, Bellinzona, Switzerland., Bertoni F; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Source: Blood [Blood] 2026 May 29. Date of Electronic Publication: 2026 May 29.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: IL-16 production is a mechanism of resistance to BTK inhibitors and R-CHOP in lymphomas.
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  Data: <searchLink fieldCode="AU" term="%22Arribas+AJ%22">Arribas AJ</searchLink>; Università della Svizzera italiana, Institute of Oncology Research, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Cannas+E%22">Cannas E</searchLink>; 1 Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Sartori+G%22">Sartori G</searchLink>; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Guidetti+F%22">Guidetti F</searchLink>; Università della Svizzera italiana, Istituto Oncologico di Ricerca.<br /><searchLink fieldCode="AU" term="%22Cascione+L%22">Cascione L</searchLink>; IOR - Institute of Oncology Research, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Napoli+S%22">Napoli S</searchLink>; Institute of Oncology Research, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Forestieri+G%22">Forestieri G</searchLink>; Institute of Oncology Research, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Fuzio+F%22">Fuzio F</searchLink>; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pesenti+EDS%22">Pesenti EDS</searchLink>; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Tarantelli+C%22">Tarantelli C</searchLink>; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Spriano+F%22">Spriano F</searchLink>; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Zucchetto+A%22">Zucchetto A</searchLink>; Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.<br /><searchLink fieldCode="AU" term="%22Rossi+FM%22">Rossi FM</searchLink>; Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.<br /><searchLink fieldCode="AU" term="%22Bruscaggin+A%22">Bruscaggin A</searchLink>; Institute of Oncology Research, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rinaldi+A%22">Rinaldi A</searchLink>; Institute of Oncology Research, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Castro+de+Moura+M%22">Castro de Moura M</searchLink>; Josep Carreras Leukaemia Research Institute, Badalona, Spain.<br /><searchLink fieldCode="AU" term="%22Jovic+S%22">Jovic S</searchLink>; Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Raimondi+A%22">Raimondi A</searchLink>; Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bordone+Pittau+R%22">Bordone Pittau R</searchLink>; IOSI Oncology Institute of Southern Switzerland.<br /><searchLink fieldCode="AU" term="%22Terzi+di+Bergamo+L%22">Terzi di Bergamo L</searchLink>; Institute of Oncology Research, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ye+X%22">Ye X</searchLink>; Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Stathis+A%22">Stathis A</searchLink>; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzoona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ben-David+Y%22">Ben-David Y</searchLink>; State Key Laboratory for Functions and Applications of Medicinal Plants, Guiyang, China.<br /><searchLink fieldCode="AU" term="%22Pan-Hammarström+Q%22">Pan-Hammarström Q</searchLink>; Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Simonetta+F%22">Simonetta F</searchLink>; Geneva University Hospitals and University of Geneva, Genève, Switzerland.<br /><searchLink fieldCode="AU" term="%22Stussi+G%22">Stussi G</searchLink>; Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Zucca+E%22">Zucca E</searchLink>; Institute of Oncology Research, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gattei+V%22">Gattei V</searchLink>; Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.<br /><searchLink fieldCode="AU" term="%22Brown+JR%22">Brown JR</searchLink>; Dana-Farber Cancer Institute, Boston, Massachusetts, United States.<br /><searchLink fieldCode="AU" term="%22Esteller+M%22">Esteller M</searchLink>; Josep Carreras Leukaemia Research Institute (IJC), Badalona, Spain.<br /><searchLink fieldCode="AU" term="%22Rossi+D%22">Rossi D</searchLink>; Institute of Oncology Research, Bellinzona, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bertoni+F%22">Bertoni F</searchLink>; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
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  Data: <searchLink fieldCode="JN" term="%227603509%22">Blood</searchLink> [Blood] 2026 May 29. <i>Date of Electronic Publication: </i>2026 May 29.
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