Canagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, attenuates pancreatic fibrosis in chronic pancreatitis through the AMPK-OPG-CTGF axis.
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| Title: | Canagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, attenuates pancreatic fibrosis in chronic pancreatitis through the AMPK-OPG-CTGF axis. |
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| Authors: | Adachi A; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan., Kato H; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan., Kato A; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan. Electronic address: akihisa@med.nagoya-cu.ac.jp., Yoshida M; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan., Hori Y; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan., Toyohara T; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan., Oda K; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan., Kito Y; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan., Urakabe K; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan., Mori T; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan., Takahashi S; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan., Kataoka H; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan. |
| Source: | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] [Pancreatology] 2026 May 25. Date of Electronic Publication: 2026 May 25. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Country of Publication: Switzerland NLM ID: 100966936 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1424-3911 (Electronic) Linking ISSN: 14243903 NLM ISO Abbreviation: Pancreatology Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42215391 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Canagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, attenuates pancreatic fibrosis in chronic pancreatitis through the AMPK-OPG-CTGF axis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Adachi+A%22">Adachi A</searchLink>; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan.<br /><searchLink fieldCode="AU" term="%22Kato+H%22">Kato H</searchLink>; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan.<br /><searchLink fieldCode="AU" term="%22Kato+A%22">Kato A</searchLink>; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan. Electronic address: akihisa@med.nagoya-cu.ac.jp.<br /><searchLink fieldCode="AU" term="%22Yoshida+M%22">Yoshida M</searchLink>; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan.<br /><searchLink fieldCode="AU" term="%22Hori+Y%22">Hori Y</searchLink>; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan.<br /><searchLink fieldCode="AU" term="%22Toyohara+T%22">Toyohara T</searchLink>; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan.<br /><searchLink fieldCode="AU" term="%22Oda+K%22">Oda K</searchLink>; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan.<br /><searchLink fieldCode="AU" term="%22Kito+Y%22">Kito Y</searchLink>; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan.<br /><searchLink fieldCode="AU" term="%22Urakabe+K%22">Urakabe K</searchLink>; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan.<br /><searchLink fieldCode="AU" term="%22Mori+T%22">Mori T</searchLink>; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan.<br /><searchLink fieldCode="AU" term="%22Takahashi+S%22">Takahashi S</searchLink>; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan.<br /><searchLink fieldCode="AU" term="%22Kataoka+H%22">Kataoka H</searchLink>; Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22100966936%22">Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]</searchLink> [Pancreatology] 2026 May 25. <i>Date of Electronic Publication: </i>2026 May 25. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22%22"> </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>100966936 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1424-3911 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214243903%22">14243903 </searchLink><i>NLM ISO Abbreviation: </i>Pancreatology <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42215391 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.pan.2026.05.006 Languages: – Code: eng Text: English Titles: – TitleFull: Canagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, attenuates pancreatic fibrosis in chronic pancreatitis through the AMPK-OPG-CTGF axis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Adachi A – PersonEntity: Name: NameFull: Kato H – PersonEntity: Name: NameFull: Kato A – PersonEntity: Name: NameFull: Yoshida M – PersonEntity: Name: NameFull: Hori Y – PersonEntity: Name: NameFull: Toyohara T – PersonEntity: Name: NameFull: Oda K – PersonEntity: Name: NameFull: Kito Y – PersonEntity: Name: NameFull: Urakabe K – PersonEntity: Name: NameFull: Mori T – PersonEntity: Name: NameFull: Takahashi S – PersonEntity: Name: NameFull: Kataoka H IsPartOfRelationships: – BibEntity: Dates: – D: 25 M: 05 Text: 2026 May 25 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1424-3911 Titles: – TitleFull: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] Type: main |
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