Arginine methylation of human DNA topoisomerase I by PRMT5 facilitates DNA relaxation.

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Title: Arginine methylation of human DNA topoisomerase I by PRMT5 facilitates DNA relaxation.
Authors: Basu S; Laboratory of Molecular Biology, School of Biological Sciences, Indian Association for the Cultivation of Science, 2A & B, Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India., Bhattacharyya A; Laboratory of Molecular Biology, School of Biological Sciences, Indian Association for the Cultivation of Science, 2A & B, Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India., Khan MA; Division of Cancer Biology, Council of Scientific and Industrial Research-Central Drug Research Institute, Lucknow 226031, India., Pal U; Technical Research Centre, S. N. Bose National Centre for Basic Sciences, Salt Lake, Kolkata 700106, India., Chowdhuri SP; Laboratory of Molecular Biology, School of Biological Sciences, Indian Association for the Cultivation of Science, 2A & B, Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India., Satrusal SR; Division of Cancer Biology, Council of Scientific and Industrial Research-Central Drug Research Institute, Lucknow 226031, India.; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh 201002, India., Baranello L; Department of Cell and Molecular Biology, Karolinska Institute, Stockholm 17177, Sweden., Datta D; Division of Cancer Biology, Council of Scientific and Industrial Research-Central Drug Research Institute, Lucknow 226031, India.; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh 201002, India., Das BB; Laboratory of Molecular Biology, School of Biological Sciences, Indian Association for the Cultivation of Science, 2A & B, Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India.
Source: Nucleic acids research [Nucleic Acids Res] 2026 May 20; Vol. 54 (10).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
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  Data: Arginine methylation of human DNA topoisomerase I by PRMT5 facilitates DNA relaxation.
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  Data: <searchLink fieldCode="AU" term="%22Basu+S%22">Basu S</searchLink>; Laboratory of Molecular Biology, School of Biological Sciences, Indian Association for the Cultivation of Science, 2A & B, Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India.<br /><searchLink fieldCode="AU" term="%22Bhattacharyya+A%22">Bhattacharyya A</searchLink>; Laboratory of Molecular Biology, School of Biological Sciences, Indian Association for the Cultivation of Science, 2A & B, Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India.<br /><searchLink fieldCode="AU" term="%22Khan+MA%22">Khan MA</searchLink>; Division of Cancer Biology, Council of Scientific and Industrial Research-Central Drug Research Institute, Lucknow 226031, India.<br /><searchLink fieldCode="AU" term="%22Pal+U%22">Pal U</searchLink>; Technical Research Centre, S. N. Bose National Centre for Basic Sciences, Salt Lake, Kolkata 700106, India.<br /><searchLink fieldCode="AU" term="%22Chowdhuri+SP%22">Chowdhuri SP</searchLink>; Laboratory of Molecular Biology, School of Biological Sciences, Indian Association for the Cultivation of Science, 2A & B, Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India.<br /><searchLink fieldCode="AU" term="%22Satrusal+SR%22">Satrusal SR</searchLink>; Division of Cancer Biology, Council of Scientific and Industrial Research-Central Drug Research Institute, Lucknow 226031, India.; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh 201002, India.<br /><searchLink fieldCode="AU" term="%22Baranello+L%22">Baranello L</searchLink>; Department of Cell and Molecular Biology, Karolinska Institute, Stockholm 17177, Sweden.<br /><searchLink fieldCode="AU" term="%22Datta+D%22">Datta D</searchLink>; Division of Cancer Biology, Council of Scientific and Industrial Research-Central Drug Research Institute, Lucknow 226031, India.; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh 201002, India.<br /><searchLink fieldCode="AU" term="%22Das+BB%22">Das BB</searchLink>; Laboratory of Molecular Biology, School of Biological Sciences, Indian Association for the Cultivation of Science, 2A & B, Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India.
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        Value: 10.1093/nar/gkag503
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              Text: 2026 May 20
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