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Structure-guided hydrophobic modulation at the 3-position of Senecio nutans-derived chalcones Drives divergent vascular mechanisms.

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Title: Structure-guided hydrophobic modulation at the 3-position of Senecio nutans-derived chalcones Drives divergent vascular mechanisms.
Authors: Palacios J; Laboratorio de Bioquímica Aplicada, Química y Farmacía, Facultad de Ciencias de la Salud, Universidad Arturo Prat, Iquique, Chile., Yu González CL; Laboratorio de Bioquímica Aplicada, Química y Farmacía, Facultad de Ciencias de la Salud, Universidad Arturo Prat, Iquique, Chile., Aravena D; Laboratorio de Bioquímica Aplicada, Química y Farmacía, Facultad de Ciencias de la Salud, Universidad Arturo Prat, Iquique, Chile., Romero-Parra J; Departamento de Química Orgánica y Fisicoquímica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago, Chile., Martínez-Cifuentes M; Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Concepción, Concepción, Chile., Parra C; Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Concepción, Concepción, Chile.
Source: Frontiers in pharmacology [Front Pharmacol] 2026 May 15; Vol. 17, pp. 1772443. Date of Electronic Publication: 2026 May 15 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Structure-guided hydrophobic modulation at the 3-position of Senecio nutans-derived chalcones Drives divergent vascular mechanisms.
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  Data: <searchLink fieldCode="AU" term="%22Palacios+J%22">Palacios J</searchLink>; Laboratorio de Bioquímica Aplicada, Química y Farmacía, Facultad de Ciencias de la Salud, Universidad Arturo Prat, Iquique, Chile.<br /><searchLink fieldCode="AU" term="%22Yu+González+CL%22">Yu González CL</searchLink>; Laboratorio de Bioquímica Aplicada, Química y Farmacía, Facultad de Ciencias de la Salud, Universidad Arturo Prat, Iquique, Chile.<br /><searchLink fieldCode="AU" term="%22Aravena+D%22">Aravena D</searchLink>; Laboratorio de Bioquímica Aplicada, Química y Farmacía, Facultad de Ciencias de la Salud, Universidad Arturo Prat, Iquique, Chile.<br /><searchLink fieldCode="AU" term="%22Romero-Parra+J%22">Romero-Parra J</searchLink>; Departamento de Química Orgánica y Fisicoquímica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Martínez-Cifuentes+M%22">Martínez-Cifuentes M</searchLink>; Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Concepción, Concepción, Chile.<br /><searchLink fieldCode="AU" term="%22Parra+C%22">Parra C</searchLink>; Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Concepción, Concepción, Chile.
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