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Real-World Effectiveness and Safety of Ofatumumab in Relapsing Multiple Sclerosis: Comparison of Treatment-Naïve Patients and Switchers in a Multicenter Cohort.

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Title: Real-World Effectiveness and Safety of Ofatumumab in Relapsing Multiple Sclerosis: Comparison of Treatment-Naïve Patients and Switchers in a Multicenter Cohort.
Authors: Mangialardi V; Neurology Unit, Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari 'Aldo Moro', Piazza Giulio Cesare 11, 70124, Bari, Italy., Macchitella G; Neurology Unit, Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari 'Aldo Moro', Piazza Giulio Cesare 11, 70124, Bari, Italy., Vitobello R; Neurology Unit, Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari 'Aldo Moro', Piazza Giulio Cesare 11, 70124, Bari, Italy., Teofilo A; Neurology Unit, Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari 'Aldo Moro', Piazza Giulio Cesare 11, 70124, Bari, Italy., Cavalli N; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, 16132, Genoa, Italy.; MS Center, IRCCS Ospedale Policlinico San Martino, 16132, Genoa, Italy., Lapucci C; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, 16132, Genoa, Italy.; MS Center, IRCCS Ospedale Policlinico San Martino, 16132, Genoa, Italy., Vercellino M; Multiple Sclerosis Center and Neurologia I U, Department of Neuroscience and Mental Health, Azienda Ospedaliero-Universitaria (AOU) Città della Salute e della Scienza di Torino, Turin, Italy., Idini E; Multiple Sclerosis Centre, ASL Cagliari, Cagliari, Italy.; Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy., Frau J; Multiple Sclerosis Centre, ASL Cagliari, Cagliari, Italy.; Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy., Iaffaldano P; Neurology Unit, Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari 'Aldo Moro', Piazza Giulio Cesare 11, 70124, Bari, Italy., Cavalla P; Multiple Sclerosis Center and Neurologia I U, Department of Neuroscience and Mental Health, Azienda Ospedaliero-Universitaria (AOU) Città della Salute e della Scienza di Torino, Turin, Italy.; Department of Neuroscience 'Rita Levi Montalcini', University of Turin, Turin, Italy., Inglese MM; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, 16132, Genoa, Italy.; MS Center, IRCCS Ospedale Policlinico San Martino, 16132, Genoa, Italy., Cocco E; Multiple Sclerosis Centre, ASL Cagliari, Cagliari, Italy.; Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy., Paolicelli D; Neurology Unit, Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari 'Aldo Moro', Piazza Giulio Cesare 11, 70124, Bari, Italy. damiano.paolicelli@uniba.it.
Source: Drugs - real world outcomes [Drugs Real World Outcomes] 2026 Jun; Vol. 13 (2), pp. 279-287. Date of Electronic Publication: 2026 May 31.
Publication Type: Journal Article
Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101658456 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2199-1154 (Print) Linking ISSN: 21989788 NLM ISO Abbreviation: Drugs Real World Outcomes Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Real-World Effectiveness and Safety of Ofatumumab in Relapsing Multiple Sclerosis: Comparison of Treatment-Naïve Patients and Switchers in a Multicenter Cohort.
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  Data: <searchLink fieldCode="AU" term="%22Mangialardi+V%22">Mangialardi V</searchLink>; Neurology Unit, Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari 'Aldo Moro', Piazza Giulio Cesare 11, 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Macchitella+G%22">Macchitella G</searchLink>; Neurology Unit, Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari 'Aldo Moro', Piazza Giulio Cesare 11, 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Vitobello+R%22">Vitobello R</searchLink>; Neurology Unit, Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari 'Aldo Moro', Piazza Giulio Cesare 11, 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Teofilo+A%22">Teofilo A</searchLink>; Neurology Unit, Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari 'Aldo Moro', Piazza Giulio Cesare 11, 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Cavalli+N%22">Cavalli N</searchLink>; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, 16132, Genoa, Italy.; MS Center, IRCCS Ospedale Policlinico San Martino, 16132, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Lapucci+C%22">Lapucci C</searchLink>; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, 16132, Genoa, Italy.; MS Center, IRCCS Ospedale Policlinico San Martino, 16132, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Vercellino+M%22">Vercellino M</searchLink>; Multiple Sclerosis Center and Neurologia I U, Department of Neuroscience and Mental Health, Azienda Ospedaliero-Universitaria (AOU) Città della Salute e della Scienza di Torino, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Idini+E%22">Idini E</searchLink>; Multiple Sclerosis Centre, ASL Cagliari, Cagliari, Italy.; Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Frau+J%22">Frau J</searchLink>; Multiple Sclerosis Centre, ASL Cagliari, Cagliari, Italy.; Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Iaffaldano+P%22">Iaffaldano P</searchLink>; Neurology Unit, Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari 'Aldo Moro', Piazza Giulio Cesare 11, 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Cavalla+P%22">Cavalla P</searchLink>; Multiple Sclerosis Center and Neurologia I U, Department of Neuroscience and Mental Health, Azienda Ospedaliero-Universitaria (AOU) Città della Salute e della Scienza di Torino, Turin, Italy.; Department of Neuroscience 'Rita Levi Montalcini', University of Turin, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Inglese+MM%22">Inglese MM</searchLink>; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, 16132, Genoa, Italy.; MS Center, IRCCS Ospedale Policlinico San Martino, 16132, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Cocco+E%22">Cocco E</searchLink>; Multiple Sclerosis Centre, ASL Cagliari, Cagliari, Italy.; Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Paolicelli+D%22">Paolicelli D</searchLink>; Neurology Unit, Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari 'Aldo Moro', Piazza Giulio Cesare 11, 70124, Bari, Italy. damiano.paolicelli@uniba.it.
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  Data: <searchLink fieldCode="JN" term="%22101658456%22">Drugs - real world outcomes</searchLink> [Drugs Real World Outcomes] 2026 Jun; Vol. 13 (2), pp. 279-287. <i>Date of Electronic Publication: </i>2026 May 31.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+International+Publishing%22">Springer International Publishing </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101658456 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2199-1154 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221989788%22">21989788 </searchLink><i>NLM ISO Abbreviation: </i>Drugs Real World Outcomes <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1007/s40801-026-00558-6
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