Combinatorial drug repurposing of Valproic acid and Zebularine regulates Krüppel-like factor 4 and β-catenin expression in colon cancer cells.
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| Title: | Combinatorial drug repurposing of Valproic acid and Zebularine regulates Krüppel-like factor 4 and β-catenin expression in colon cancer cells. |
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| Authors: | Kandhavelu J; Oncology Division, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Subramanian K; Oncology Division, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Moodley N; Oncology Division, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Abass KS; College of Veterinary Medicine, Department of Physiology, Biochemistry, and Pharmacology, University of Kirkuk, Kirkuk, Iraq., Sureka C; Department of Basic Medical Sciences, College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia., Kandhavelu M; Molecular Signaling Group, Faculty of Medicine and Health Technology, BioMediTech, Tampere University and Tays Cancer Center, Tampere, Finland., Ruff P; Oncology Division, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Penny C; Oncology Division, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. |
| Source: | PloS one [PLoS One] 2026 Jun 01; Vol. 21 (6), pp. e0348215. Date of Electronic Publication: 2026 Jun 01 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1932-6203 |
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| DOI: | 10.1371/journal.pone.0348215 |
