Standardized workflow enables reproducibility of drug synergism detection: Results from a multi-center in vitro ring test on complex drug combinations in pancreatic cancer models.
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| Title: | Standardized workflow enables reproducibility of drug synergism detection: Results from a multi-center in vitro ring test on complex drug combinations in pancreatic cancer models. |
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| Authors: | Barile V; Experimental Pharmacology Unit-Laboratory of Naples and Mercogliano (AV), Istituto Nazionale per lo Studio e la Cura dei Tumori 'Fondazione G. Pascale' - IRCCS, Naples, Italy., Kuzikov M; Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Schnackenburgallee 114, Hamburg D-22525 Germany., Cui W; Chemical Biology Consortium Sweden (CBCS), Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden., Ianevski A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Iannelli F; Experimental Pharmacology Unit-Laboratory of Naples and Mercogliano (AV), Istituto Nazionale per lo Studio e la Cura dei Tumori 'Fondazione G. Pascale' - IRCCS, Naples, Italy., Roca MS; Experimental Pharmacology Unit-Laboratory of Naples and Mercogliano (AV), Istituto Nazionale per lo Studio e la Cura dei Tumori 'Fondazione G. Pascale' - IRCCS, Naples, Italy., Reinshagen J; Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Schnackenburgallee 114, Hamburg D-22525 Germany., Axelsson H; Chemical Biology Consortium Sweden (CBCS), Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden., Leone A; Experimental Pharmacology Unit-Laboratory of Naples and Mercogliano (AV), Istituto Nazionale per lo Studio e la Cura dei Tumori 'Fondazione G. Pascale' - IRCCS, Naples, Italy., Jenmalm Jensen A; Chemical Biology Consortium Sweden (CBCS), Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden., Aittokallio T; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland; Institute for Cancer Research, Department of Cancer Genetics, Oslo University Hospital, Oslo, Norway; Oslo Centre for Biostatistics and Epidemiology (OCBE), Faculty of Medicine, University of Oslo, Oslo, Norway., Gribbon P; Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Schnackenburgallee 114, Hamburg D-22525 Germany., Seashore-Ludlow B; Chemical Biology Consortium Sweden (CBCS), Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden., Budillon A; Scientific Directorate, Istituto Nazionale per lo Studio e la Cura dei Tumori 'Fondazione G. Pascale' - IRCCS, Naples, Italy. Electronic address: a.budillon@istitutotumori.na.it. |
| Source: | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2026 Jul; Vol. 200, pp. 119575. Date of Electronic Publication: 2026 Jun 01. |
| Publication Type: | Journal Article; Multicenter Study |
| Journal Info: | Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42224741 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Standardized workflow enables reproducibility of drug synergism detection: Results from a multi-center in vitro ring test on complex drug combinations in pancreatic cancer models. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Barile+V%22">Barile V</searchLink>; Experimental Pharmacology Unit-Laboratory of Naples and Mercogliano (AV), Istituto Nazionale per lo Studio e la Cura dei Tumori 'Fondazione G. Pascale' - IRCCS, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Kuzikov+M%22">Kuzikov M</searchLink>; Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Schnackenburgallee 114, Hamburg D-22525 Germany.<br /><searchLink fieldCode="AU" term="%22Cui+W%22">Cui W</searchLink>; Chemical Biology Consortium Sweden (CBCS), Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Ianevski+A%22">Ianevski A</searchLink>; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Iannelli+F%22">Iannelli F</searchLink>; Experimental Pharmacology Unit-Laboratory of Naples and Mercogliano (AV), Istituto Nazionale per lo Studio e la Cura dei Tumori 'Fondazione G. Pascale' - IRCCS, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Roca+MS%22">Roca MS</searchLink>; Experimental Pharmacology Unit-Laboratory of Naples and Mercogliano (AV), Istituto Nazionale per lo Studio e la Cura dei Tumori 'Fondazione G. Pascale' - IRCCS, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Reinshagen+J%22">Reinshagen J</searchLink>; Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Schnackenburgallee 114, Hamburg D-22525 Germany.<br /><searchLink fieldCode="AU" term="%22Axelsson+H%22">Axelsson H</searchLink>; Chemical Biology Consortium Sweden (CBCS), Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Leone+A%22">Leone A</searchLink>; Experimental Pharmacology Unit-Laboratory of Naples and Mercogliano (AV), Istituto Nazionale per lo Studio e la Cura dei Tumori 'Fondazione G. Pascale' - IRCCS, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Jenmalm+Jensen+A%22">Jenmalm Jensen A</searchLink>; Chemical Biology Consortium Sweden (CBCS), Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Aittokallio+T%22">Aittokallio T</searchLink>; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland; Institute for Cancer Research, Department of Cancer Genetics, Oslo University Hospital, Oslo, Norway; Oslo Centre for Biostatistics and Epidemiology (OCBE), Faculty of Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Gribbon+P%22">Gribbon P</searchLink>; Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Schnackenburgallee 114, Hamburg D-22525 Germany.<br /><searchLink fieldCode="AU" term="%22Seashore-Ludlow+B%22">Seashore-Ludlow B</searchLink>; Chemical Biology Consortium Sweden (CBCS), Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Budillon+A%22">Budillon A</searchLink>; Scientific Directorate, Istituto Nazionale per lo Studio e la Cura dei Tumori 'Fondazione G. Pascale' - IRCCS, Naples, Italy. Electronic address: a.budillon@istitutotumori.na.it. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228213295%22">Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie</searchLink> [Biomed Pharmacother] 2026 Jul; Vol. 200, pp. 119575. <i>Date of Electronic Publication: </i>2026 Jun 01. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Multicenter Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Editions+Scientifiques+Elsevier%22">Editions Scientifiques Elsevier </searchLink><i>Country of Publication: </i>France <i>NLM ID: </i>8213295 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1950-6007 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207533322%22">07533322 </searchLink><i>NLM ISO Abbreviation: </i>Biomed Pharmacother <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42224741 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.biopha.2026.119575 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 119575 Titles: – TitleFull: Standardized workflow enables reproducibility of drug synergism detection: Results from a multi-center in vitro ring test on complex drug combinations in pancreatic cancer models. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Barile V – PersonEntity: Name: NameFull: Kuzikov M – PersonEntity: Name: NameFull: Cui W – PersonEntity: Name: NameFull: Ianevski A – PersonEntity: Name: NameFull: Iannelli F – PersonEntity: Name: NameFull: Roca MS – PersonEntity: Name: NameFull: Reinshagen J – PersonEntity: Name: NameFull: Axelsson H – PersonEntity: Name: NameFull: Leone A – PersonEntity: Name: NameFull: Jenmalm Jensen A – PersonEntity: Name: NameFull: Aittokallio T – PersonEntity: Name: NameFull: Gribbon P – PersonEntity: Name: NameFull: Seashore-Ludlow B – PersonEntity: Name: NameFull: Budillon A IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: 2026 Jul Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1950-6007 Numbering: – Type: volume Value: 200 Titles: – TitleFull: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Type: main |
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