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Population pharmacokinetics of polymyxin B: an individual participant data meta-analysis.

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Title: Population pharmacokinetics of polymyxin B: an individual participant data meta-analysis.
Authors: Matcha S; Titus Family Department of Clinical Pharmacy, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA, USA; Center for Quantitative Drug and Disease Modelling, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA, USA., Rao GG; Titus Family Department of Clinical Pharmacy, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA, USA; Center for Quantitative Drug and Disease Modelling, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA, USA. Electronic address: gaurirao@usc.edu., Hanafin PO; Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Liu X; Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China; Key Laboratory of Clinical Pharmacology of Antibiotics, National Health Commission of the People's Republic of China, Shanghai, China; National Clinical Research Centre for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China., Yu Z; Sir Run Run Shaw Hospital, School of Medicine, Zhenjiang University, Hangzhou, China., Zhang J; Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China; Key Laboratory of Clinical Pharmacology of Antibiotics, National Health Commission of the People's Republic of China, Shanghai, China; National Clinical Research Centre for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China., Qiu H; Department of Pharmacy, Fujian Medical University Union Hospital, Fuzhou, China; College of Pharmacy, Fujian Medical University, Fuzhou, China., Cheng Y; Department of Pharmacy, Fujian Medical University Union Hospital, Fuzhou, China; College of Pharmacy, Fujian Medical University, Fuzhou, China., Zavascki AP; Infectious Diseases Service, Hospital Moinhos de Vento, Porto Alegre, Brazil; Department of Internal Medicine, Medical School, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Sandri AM; Infectious Disease Service, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil; Department of Internal Medicine, Medical School, Universidade Federal de Ciências da Saúde de Porto Alegre/Rio Grande do Sul, Porto Alegre, Brazil., Kwa A; Department of Pharmacy, Singapore General Hospital, Singapore; Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore., Scheetz MH; Department of Pharmacy Practice, Midwestern University Chicago College of Pharmacy, Downers Grove, IL, USA., Kubin CJ; Department of Pharmacy and Division of Infectious Diseases, New York-Presbyterian Hospital/Columbia University Irving Medical Center, New York, NY, USA., Shah J; Division of Infectious Diseases, Department of Internal Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA., Cherng BPZ; Department of Infectious Diseases, Singapore General Hospital, Singapore, Singapore., Yin MT; Division of Infectious Diseases, Department of Internal Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA., Wang J; Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Wang L; Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Calfee DP; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Bolon M; Department of Healthcare Epidemiology and Infection Prevention, Northwestern Memorial Hospital, Chicago, IL, USA; Department of Medicine, Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Purcell AW; Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia., Nation RL; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia., Pogue JM; Department of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, MI, USA., Kaye KS; Division of Allergy, Immunology and Infectious Diseases, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA., Li J; Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia. Electronic address: jian.li@monash.edu.
Source: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases [Clin Microbiol Infect] 2026 Jun 01. Date of Electronic Publication: 2026 Jun 01.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9516420 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-0691 (Electronic) Linking ISSN: 1198743X NLM ISO Abbreviation: Clin Microbiol Infect Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Population pharmacokinetics of polymyxin B: an individual participant data meta-analysis.
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  Data: <searchLink fieldCode="AU" term="%22Matcha+S%22">Matcha S</searchLink>; Titus Family Department of Clinical Pharmacy, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA, USA; Center for Quantitative Drug and Disease Modelling, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rao+GG%22">Rao GG</searchLink>; Titus Family Department of Clinical Pharmacy, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA, USA; Center for Quantitative Drug and Disease Modelling, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA, USA. Electronic address: gaurirao@usc.edu.<br /><searchLink fieldCode="AU" term="%22Hanafin+PO%22">Hanafin PO</searchLink>; Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China; Key Laboratory of Clinical Pharmacology of Antibiotics, National Health Commission of the People's Republic of China, Shanghai, China; National Clinical Research Centre for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yu+Z%22">Yu Z</searchLink>; Sir Run Run Shaw Hospital, School of Medicine, Zhenjiang University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China; Key Laboratory of Clinical Pharmacology of Antibiotics, National Health Commission of the People's Republic of China, Shanghai, China; National Clinical Research Centre for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Qiu+H%22">Qiu H</searchLink>; Department of Pharmacy, Fujian Medical University Union Hospital, Fuzhou, China; College of Pharmacy, Fujian Medical University, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Cheng+Y%22">Cheng Y</searchLink>; Department of Pharmacy, Fujian Medical University Union Hospital, Fuzhou, China; College of Pharmacy, Fujian Medical University, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Zavascki+AP%22">Zavascki AP</searchLink>; Infectious Diseases Service, Hospital Moinhos de Vento, Porto Alegre, Brazil; Department of Internal Medicine, Medical School, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.<br /><searchLink fieldCode="AU" term="%22Sandri+AM%22">Sandri AM</searchLink>; Infectious Disease Service, Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil; Department of Internal Medicine, Medical School, Universidade Federal de Ciências da Saúde de Porto Alegre/Rio Grande do Sul, Porto Alegre, Brazil.<br /><searchLink fieldCode="AU" term="%22Kwa+A%22">Kwa A</searchLink>; Department of Pharmacy, Singapore General Hospital, Singapore; Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Scheetz+MH%22">Scheetz MH</searchLink>; Department of Pharmacy Practice, Midwestern University Chicago College of Pharmacy, Downers Grove, IL, USA.<br /><searchLink fieldCode="AU" term="%22Kubin+CJ%22">Kubin CJ</searchLink>; Department of Pharmacy and Division of Infectious Diseases, New York-Presbyterian Hospital/Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Shah+J%22">Shah J</searchLink>; Division of Infectious Diseases, Department of Internal Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Cherng+BPZ%22">Cherng BPZ</searchLink>; Department of Infectious Diseases, Singapore General Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Yin+MT%22">Yin MT</searchLink>; Division of Infectious Diseases, Department of Internal Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Calfee+DP%22">Calfee DP</searchLink>; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bolon+M%22">Bolon M</searchLink>; Department of Healthcare Epidemiology and Infection Prevention, Northwestern Memorial Hospital, Chicago, IL, USA; Department of Medicine, Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Purcell+AW%22">Purcell AW</searchLink>; Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Nation+RL%22">Nation RL</searchLink>; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Pogue+JM%22">Pogue JM</searchLink>; Department of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Kaye+KS%22">Kaye KS</searchLink>; Division of Allergy, Immunology and Infectious Diseases, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia. Electronic address: jian.li@monash.edu.
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