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Direct-to-definitive urine drug screening in children unmasks false-negative immunoassay screening.

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Title: Direct-to-definitive urine drug screening in children unmasks false-negative immunoassay screening.
Authors: Lin Y; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA., El-Khoury JM; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA., Garg UC; Department of Pathology and Laboratory Medicine, Children's Mercy Hospital, Kansas City, MO, USA., Jones PM; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Lo SF; Department of Pathology and Laboratory Medicine, Medical College of Wisconsin, Children's Wisconsin, Milwaukee, WI, USA., Patel K; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Roper SM; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA., Dietzen DJ; Department of Pathology and Laboratory Medicine, Phoenix Children's Hospital, Phoenix, AZ, USA. Electronic address: ddietzen@phoenixchildrens.com.
Source: Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2026 Jun 01; Vol. 591, pp. 121136. Date of Electronic Publication: 2026 Jun 01.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 1302422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3492 (Electronic) Linking ISSN: 00098981 NLM ISO Abbreviation: Clin Chim Acta Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Direct-to-definitive urine drug screening in children unmasks false-negative immunoassay screening.
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  Data: <searchLink fieldCode="AU" term="%22Lin+Y%22">Lin Y</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22El-Khoury+JM%22">El-Khoury JM</searchLink>; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Garg+UC%22">Garg UC</searchLink>; Department of Pathology and Laboratory Medicine, Children's Mercy Hospital, Kansas City, MO, USA.<br /><searchLink fieldCode="AU" term="%22Jones+PM%22">Jones PM</searchLink>; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Lo+SF%22">Lo SF</searchLink>; Department of Pathology and Laboratory Medicine, Medical College of Wisconsin, Children's Wisconsin, Milwaukee, WI, USA.<br /><searchLink fieldCode="AU" term="%22Patel+K%22">Patel K</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Roper+SM%22">Roper SM</searchLink>; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Dietzen+DJ%22">Dietzen DJ</searchLink>; Department of Pathology and Laboratory Medicine, Phoenix Children's Hospital, Phoenix, AZ, USA. Electronic address: ddietzen@phoenixchildrens.com.
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  Data: <searchLink fieldCode="JN" term="%221302422%22">Clinica chimica acta; international journal of clinical chemistry</searchLink> [Clin Chim Acta] 2026 Jun 01; Vol. 591, pp. 121136. <i>Date of Electronic Publication: </i>2026 Jun 01.
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        Value: 10.1016/j.cca.2026.121136
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              Text: 2026 Jun 01
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