Chimeric antigen receptor T-cell therapy is equally effective and safe in older (≥70) and younger patients with multiple myeloma: a multicenter retrospective analysis.

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Title: Chimeric antigen receptor T-cell therapy is equally effective and safe in older (≥70) and younger patients with multiple myeloma: a multicenter retrospective analysis.
Authors: Berning P; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Muenster, Muenster, Germany., Maulhardt M; Department of Hematology and Medical Oncology, University Hospital Goettingen, Goettingen, Germany., Boyadzhiev H; Department of Medical Oncology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland.; Habichtswald Hospital, Kassel, Germany., Albici AM; University Hospital Schleswig-Holstein, Kiel, Division of Stem Cell Transplantation and Cellular Immunotherapies, Kiel University, Kiel, Germany., Janjetovic S; Department of Hematology, Oncology, and Tumor Immunology Helios Klinikum Berlin-Buch, Berlin, Germany., Ossami Saidy A; Department of Hematology, Oncology, and Tumor Immunology Helios Klinikum Berlin-Buch, Berlin, Germany., Schultze-Florey C; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany., Call S; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Muenster, Muenster, Germany., Stölzel F; University Hospital Schleswig-Holstein, Kiel, Division of Stem Cell Transplantation and Cellular Immunotherapies, Kiel University, Kiel, Germany., Brioli A; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany., Daskalakis M; Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Knust J; Department of Hematology and Medical Oncology, University Hospital Goettingen, Goettingen, Germany., Hasenkamp J; Department of Hematology and Medical Oncology, University Hospital Goettingen, Goettingen, Germany., Wurm-Kuczera R; Department of Hematology, Oncology, and Cancer Immunology, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Pohlmann A; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Muenster, Muenster, Germany., Stelljes M; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Muenster, Muenster, Germany., Khandanpour C; Department of Hematology and Oncology, University Hospital of Schleswig-Holstein, University of Lübeck, Lübeck, Germany., Bacher U; Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Boquoi A; Department of Hematology and Stem Cell Transplantation, West German Cancer Center and German Cancer consortium (DKTK partner site Essen), University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Heidel FH; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.; Cellular Therapy Center (CTC), Hannover Medical School (MHH), Hannover, Germany., Reinhardt HC; Department of Hematology and Stem Cell Transplantation, West German Cancer Center and German Cancer consortium (DKTK partner site Essen), University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Wulf G; Department of Hematology and Medical Oncology, University Hospital Goettingen, Goettingen, Germany., Schub N; University Hospital Schleswig-Holstein, Kiel, Division of Stem Cell Transplantation and Cellular Immunotherapies, Kiel University, Kiel, Germany., von Tresckow B; Department of Hematology and Stem Cell Transplantation, West German Cancer Center and German Cancer consortium (DKTK partner site Essen), University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Lenz G; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Muenster, Muenster, Germany., Pabst T; Department of Medical Oncology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland., Shumilov E; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Muenster, Muenster, Germany. evgenii.shumilov@ukmuenster.de.
Source: Blood cancer journal [Blood Cancer J] 2026 Jun 02; Vol. 16 (1). Date of Electronic Publication: 2026 Jun 02.
Publication Type: Letter
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101568469 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-5385 (Electronic) Linking ISSN: 20445385 NLM ISO Abbreviation: Blood Cancer J Subsets: MEDLINE; In Process
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  Data: Chimeric antigen receptor T-cell therapy is equally effective and safe in older (≥70) and younger patients with multiple myeloma: a multicenter retrospective analysis.
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  Data: <searchLink fieldCode="AU" term="%22Berning+P%22">Berning P</searchLink>; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Muenster, Muenster, Germany.<br /><searchLink fieldCode="AU" term="%22Maulhardt+M%22">Maulhardt M</searchLink>; Department of Hematology and Medical Oncology, University Hospital Goettingen, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Boyadzhiev+H%22">Boyadzhiev H</searchLink>; Department of Medical Oncology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland.; Habichtswald Hospital, Kassel, Germany.<br /><searchLink fieldCode="AU" term="%22Albici+AM%22">Albici AM</searchLink>; University Hospital Schleswig-Holstein, Kiel, Division of Stem Cell Transplantation and Cellular Immunotherapies, Kiel University, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Janjetovic+S%22">Janjetovic S</searchLink>; Department of Hematology, Oncology, and Tumor Immunology Helios Klinikum Berlin-Buch, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Ossami+Saidy+A%22">Ossami Saidy A</searchLink>; Department of Hematology, Oncology, and Tumor Immunology Helios Klinikum Berlin-Buch, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Schultze-Florey+C%22">Schultze-Florey C</searchLink>; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Call+S%22">Call S</searchLink>; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Muenster, Muenster, Germany.<br /><searchLink fieldCode="AU" term="%22Stölzel+F%22">Stölzel F</searchLink>; University Hospital Schleswig-Holstein, Kiel, Division of Stem Cell Transplantation and Cellular Immunotherapies, Kiel University, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Brioli+A%22">Brioli A</searchLink>; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Daskalakis+M%22">Daskalakis M</searchLink>; Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Knust+J%22">Knust J</searchLink>; Department of Hematology and Medical Oncology, University Hospital Goettingen, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Hasenkamp+J%22">Hasenkamp J</searchLink>; Department of Hematology and Medical Oncology, University Hospital Goettingen, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Wurm-Kuczera+R%22">Wurm-Kuczera R</searchLink>; Department of Hematology, Oncology, and Cancer Immunology, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Pohlmann+A%22">Pohlmann A</searchLink>; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Muenster, Muenster, Germany.<br /><searchLink fieldCode="AU" term="%22Stelljes+M%22">Stelljes M</searchLink>; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Muenster, Muenster, Germany.<br /><searchLink fieldCode="AU" term="%22Khandanpour+C%22">Khandanpour C</searchLink>; Department of Hematology and Oncology, University Hospital of Schleswig-Holstein, University of Lübeck, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Bacher+U%22">Bacher U</searchLink>; Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Boquoi+A%22">Boquoi A</searchLink>; Department of Hematology and Stem Cell Transplantation, West German Cancer Center and German Cancer consortium (DKTK partner site Essen), University Hospital Essen, University of Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Heidel+FH%22">Heidel FH</searchLink>; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.; Cellular Therapy Center (CTC), Hannover Medical School (MHH), Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Reinhardt+HC%22">Reinhardt HC</searchLink>; Department of Hematology and Stem Cell Transplantation, West German Cancer Center and German Cancer consortium (DKTK partner site Essen), University Hospital Essen, University of Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Wulf+G%22">Wulf G</searchLink>; Department of Hematology and Medical Oncology, University Hospital Goettingen, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Schub+N%22">Schub N</searchLink>; University Hospital Schleswig-Holstein, Kiel, Division of Stem Cell Transplantation and Cellular Immunotherapies, Kiel University, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22von+Tresckow+B%22">von Tresckow B</searchLink>; Department of Hematology and Stem Cell Transplantation, West German Cancer Center and German Cancer consortium (DKTK partner site Essen), University Hospital Essen, University of Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Lenz+G%22">Lenz G</searchLink>; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Muenster, Muenster, Germany.<br /><searchLink fieldCode="AU" term="%22Pabst+T%22">Pabst T</searchLink>; Department of Medical Oncology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Shumilov+E%22">Shumilov E</searchLink>; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Muenster, Muenster, Germany. evgenii.shumilov@ukmuenster.de.
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