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Myo-inositol concentration in the medial prefrontal cortex is associated with changes in brain white matter microstructure in early psychosis.

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Title: Myo-inositol concentration in the medial prefrontal cortex is associated with changes in brain white matter microstructure in early psychosis.
Authors: Pavan T; Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland. tommaso.pavan@chuv.ch., Wang Q; Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland., Alemán-Gómez Y; Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland., Jenni R; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Cleusix M; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Alameda L; Service of General Psychiatry, Treatment and Early Intervention in Psychosis Program. Lausanne University Hospital (CHUV), Lausanne, Switzerland.; Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience. King's College of London, London, UK.; Centro Investigacion Biomedica en Red de Salud Mental (CIBERSAM); Instituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocio, Departamento de Psiquiatria, Universidad de Sevilla, Sevilla, Spain., Q Do K; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Conus P; Service of General Psychiatry, Treatment and Early Intervention in Psychosis Program. Lausanne University Hospital (CHUV), Lausanne, Switzerland., Hagmann P; Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland., Steullet P; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Klauser P; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Division of Child and Adolescent Psychiatry, Department of Psychiatry, Lausanne University Hospital and the University of Lausanne, Lausanne, Switzerland., Xin L; Center for Biomedical Imaging (CIBM), Lausanne, Switzerland.; Institute of Physics (IPHYS), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland., Jelescu I; Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.
Source: Translational psychiatry [Transl Psychiatry] 2026 Jun 02. Date of Electronic Publication: 2026 Jun 02.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
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  Data: Myo-inositol concentration in the medial prefrontal cortex is associated with changes in brain white matter microstructure in early psychosis.
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  Data: <searchLink fieldCode="AU" term="%22Pavan+T%22">Pavan T</searchLink>; Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland. tommaso.pavan@chuv.ch.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Alemán-Gómez+Y%22">Alemán-Gómez Y</searchLink>; Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Jenni+R%22">Jenni R</searchLink>; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Cleusix+M%22">Cleusix M</searchLink>; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Alameda+L%22">Alameda L</searchLink>; Service of General Psychiatry, Treatment and Early Intervention in Psychosis Program. Lausanne University Hospital (CHUV), Lausanne, Switzerland.; Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience. King's College of London, London, UK.; Centro Investigacion Biomedica en Red de Salud Mental (CIBERSAM); Instituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocio, Departamento de Psiquiatria, Universidad de Sevilla, Sevilla, Spain.<br /><searchLink fieldCode="AU" term="%22Q+Do+K%22">Q Do K</searchLink>; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Conus+P%22">Conus P</searchLink>; Service of General Psychiatry, Treatment and Early Intervention in Psychosis Program. Lausanne University Hospital (CHUV), Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hagmann+P%22">Hagmann P</searchLink>; Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Steullet+P%22">Steullet P</searchLink>; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Klauser+P%22">Klauser P</searchLink>; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Division of Child and Adolescent Psychiatry, Department of Psychiatry, Lausanne University Hospital and the University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Xin+L%22">Xin L</searchLink>; Center for Biomedical Imaging (CIBM), Lausanne, Switzerland.; Institute of Physics (IPHYS), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Jelescu+I%22">Jelescu I</searchLink>; Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.
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              Text: 2026 Jun 02
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