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Distinct transcription factors control tissue adaptation and effector function in infant and adult memory T cells.

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Title: Distinct transcription factors control tissue adaptation and effector function in infant and adult memory T cells.
Authors: Szabo PA; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Levitin HM; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA., Nargund S; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA., Connors TJ; Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA., Chen D; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA., Jin J; Medical Scientist Training Program, Columbia University Irving Medical Center, New York, NY, USA., Thapa P; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Guyer R; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Caron DP; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Gray JI; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Matsumoto R; Department of Surgery, Columbia University Irving Medical Center, New York, NY, USA., Kubota M; Department of Surgery, Columbia University Irving Medical Center, New York, NY, USA., Brusko M; Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL, USA., Brusko TM; Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL, USA., Farber DL; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA. df2396@cumc.columbia.edu.; Department of Surgery, Columbia University Irving Medical Center, New York, NY, USA. df2396@cumc.columbia.edu., Sims PA; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA. pas2182@cumc.columbia.edu.; Department of Biochemistry and Molecular Biophysics, Columbia University Irving Medical Center, New York, NY, USA. pas2182@cumc.columbia.edu.
Source: Nature immunology [Nat Immunol] 2026 Jul; Vol. 27 (7), pp. 1517-1527. Date of Electronic Publication: 2026 Jun 02.
Publication Type: Journal Article
Journal Info: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE
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              Text: 2026 Jul
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