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WTAP tetramer ensures m6A writer assembly and faithful mitosis.

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Title: WTAP tetramer ensures m6A writer assembly and faithful mitosis.
Authors: Zhang S; Department of Neurology, the First Affiliated Hospital of USTC, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Biomedical Sciences and Health Laboratory of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China., Ye J; Department of Neurology, the First Affiliated Hospital of USTC, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Biomedical Sciences and Health Laboratory of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.; School of Life Sciences, East China Normal University, Shanghai, China., Zhang M; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China., Cao J; Ministry of Education Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China., Li Y; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China., Hu R; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China., Chen D; Department of Neurology, the First Affiliated Hospital of USTC, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Biomedical Sciences and Health Laboratory of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China., Li T; Ministry of Education Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China., Chen J; Department of Neurology, the First Affiliated Hospital of USTC, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Biomedical Sciences and Health Laboratory of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China., Zhu W; Department of Neurology, the First Affiliated Hospital of USTC, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Biomedical Sciences and Health Laboratory of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China., Jiang W; Department of Neurology, the First Affiliated Hospital of USTC, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Biomedical Sciences and Health Laboratory of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China., Li J; Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology, Guangzhou, China., Hu W; Department of Neurology, the First Affiliated Hospital of USTC, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Biomedical Sciences and Health Laboratory of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. andinghu@ustc.edu.cn., Liu J; Ministry of Education Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China. liujz@zju.edu.cn., Liu X; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China. xing1017@ustc.edu.cn., Wang C; Department of Neurology, the First Affiliated Hospital of USTC, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Biomedical Sciences and Health Laboratory of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. cwangust@ustc.edu.cn.; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China. cwangust@ustc.edu.cn.
Source: EMBO reports [EMBO Rep] 2026 Jun 02. Date of Electronic Publication: 2026 Jun 02.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE
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  Data: WTAP tetramer ensures m<superscript>6</superscript>A writer assembly and faithful mitosis.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Department of Neurology, the First Affiliated Hospital of USTC, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Biomedical Sciences and Health Laboratory of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.<br /><searchLink fieldCode="AU" term="%22Ye+J%22">Ye J</searchLink>; Department of Neurology, the First Affiliated Hospital of USTC, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Biomedical Sciences and Health Laboratory of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.; School of Life Sciences, East China Normal University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhang+M%22">Zhang M</searchLink>; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.<br /><searchLink fieldCode="AU" term="%22Cao+J%22">Cao J</searchLink>; Ministry of Education Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.<br /><searchLink fieldCode="AU" term="%22Hu+R%22">Hu R</searchLink>; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.<br /><searchLink fieldCode="AU" term="%22Chen+D%22">Chen D</searchLink>; Department of Neurology, the First Affiliated Hospital of USTC, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Biomedical Sciences and Health Laboratory of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.<br /><searchLink fieldCode="AU" term="%22Li+T%22">Li T</searchLink>; Ministry of Education Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Neurology, the First Affiliated Hospital of USTC, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Biomedical Sciences and Health Laboratory of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.<br /><searchLink fieldCode="AU" term="%22Zhu+W%22">Zhu W</searchLink>; Department of Neurology, the First Affiliated Hospital of USTC, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Biomedical Sciences and Health Laboratory of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.<br /><searchLink fieldCode="AU" term="%22Jiang+W%22">Jiang W</searchLink>; Department of Neurology, the First Affiliated Hospital of USTC, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Biomedical Sciences and Health Laboratory of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Hu+W%22">Hu W</searchLink>; Department of Neurology, the First Affiliated Hospital of USTC, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Biomedical Sciences and Health Laboratory of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. andinghu@ustc.edu.cn.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Ministry of Education Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China. liujz@zju.edu.cn.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China. xing1017@ustc.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Department of Neurology, the First Affiliated Hospital of USTC, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Biomedical Sciences and Health Laboratory of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. cwangust@ustc.edu.cn.; Ministry of Education Key Laboratory for Membrane-less Organelles and Cellular Dynamics, Hefei National Research Center for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China. cwangust@ustc.edu.cn.
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