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Real-World Comparison of First-Line Atezolizumab plus Bevacizumab and Durvalumab plus Tremelimumab for Unresectable Hepatocellular Carcinoma.

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Title: Real-World Comparison of First-Line Atezolizumab plus Bevacizumab and Durvalumab plus Tremelimumab for Unresectable Hepatocellular Carcinoma.
Authors: Hiraoka A; Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama, Japan., Tada T; Department of Internal Medicine, Japanese Red Cross Society Himeji Hospital, Himeji, Japan.; Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan., Hirooka M; Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Japan., Kariyama K; Department of Gastroenterology, Okayama City Hospital, Okayama, Japan., Tani J; Department of Gastroenterology and Neurology, Kagawa University, Takamatsu, Japan., Atsukawa M; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nippon Medical School, Tokyo, Japan., Takaguchi K; Department of Hepatology, Kagawa Prefectural Central Hospital, Takamatsu, Japan., Itobayashi E; Department of Gastroenterology, Asahi General Hospital, Asahi, Japan., Nishimura T; Department of Gastroenterology, Hyogo Medical University, Nishinomiya, Japan., Tsuji K; Center for Gastroenterology, Teine Keijinkai Hospital, Sapporo, Japan., Ishikawa T; Department of Gastroenterology, Saiseikai Niigata Hospital, Niigata, Japan., Tajiri K; Department of Gastroenterology, Toyama University Hospital, Toyama, Japan., Tanaka H; Takarazuka City Hospital, Department of Gastroenterology, Hyogo, Japan., Toyoda H; Department of Gastroenterology and Hepatology, Ogaki Municipal Hospital, Ogaki, Japan., Ogawa C; Department of Gastroenterology, Japanese Red Cross Takamatsu Hospital, Takamatsu, Japan., Hatanaka T; Department of Gastroenterology, Gunma Saiseikai Maebashi Hospital, Maebashi, Japan., Kakizaki S; Department of Clinical Research, NHO Takasaki General Medical Center, Takasaki, Japan., Kawata K; Hepatology Division, Department of Internal Medicine II, Hamamatsu University School of Medicine, Hamamatsu, Japan., Naganuma A; Department of Gastroenterology, NHO Takasaki General Medical Center, Takasaki, Japan., Kosaka H; Department of Hepatobiliary Surgery, Kansai Medical University, Hirakata, Japan., Matono T; Department of Gastroenterology, Harima Himeji General Medical Center, Himeji, Japan., Kuroda H; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Iwate Medical University School of Medicine, Morioka, Japan., Yata Y; Department of Gastroenterology, Hanwa Memorial Hospital, Osaka, Japan., Nishikawa H; Department of Gastroenterology, Osaka Medical and Pharmaceutical University, Osaka, Japan., Imai M; Department of Gastroenterology, Saiseikai Niigata Hospital, Niigata, Japan.; Department of Gastroenterology, Niigata Prefectural Cancer Center, Niigata, Japan., Aoki T; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka, Japan., Ochi H; Center for Liver-Biliary-Pancreatic Disease, Japanese Red Cross Matsuyama Hospital, Matsuyama, Japan., Tamai H; Department of Hepatology, Wakayama Rosai Hospital, Wakayama, Japan., Komatsu S; Department of Surgery, Division of Hepato-Biliary-Pancreatic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan., Matsuura T; Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan., Ueda Y; Department of Gastroenterology, Kakogawa City Hospital, Kakogawa, Japan., Kim SK; Department of Gastroenterology, Kobe Asahi Hospital, Kobe, Japan., Ohama H; Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama, Japan., Tada F; Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama, Japan., Nakamura S; Department of Internal Medicine, Japanese Red Cross Society Himeji Hospital, Himeji, Japan., Nakamura Y; Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Japan., Yoshida O; Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Japan., Nouso K; Department of Gastroenterology, Okayama City Hospital, Okayama, Japan., Morishita A; Department of Gastroenterology and Neurology, Kagawa University, Takamatsu, Japan., Itokawa N; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nippon Medical School, Tokyo, Japan., Okubo T; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nippon Medical School, Tokyo, Japan., Arai T; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nippon Medical School, Tokyo, Japan., Tsutsui A; Department of Hepatology, Kagawa Prefectural Central Hospital, Takamatsu, Japan., Nagano T; Department of Hepatology, Kagawa Prefectural Central Hospital, Takamatsu, Japan., Fukunishi S; Department of Gastroenterology, Hyogo Medical University, Nishinomiya, Japan., Tanaka K; Center for Gastroenterology, Teine Keijinkai Hospital, Sapporo, Japan., Koshiyama Y; Department of Gastroenterology and Hepatology, Ogaki Municipal Hospital, Ogaki, Japan., Kanayama Y; Department of Gastroenterology, Gunma Saiseikai Maebashi Hospital, Maebashi, Japan., Noritake H; Hepatology Division, Department of Internal Medicine II, Hamamatsu University School of Medicine, Hamamatsu, Japan., Enomoto H; Department of Gastroenterology, Hyogo Medical University, Nishinomiya, Japan., Matsui K; Department of Hepatobiliary Surgery, Kansai Medical University, Hirakata, Japan., Kaibori M; Department of Hepatobiliary Surgery, Kansai Medical University, Hirakata, Japan., Okamura J; Department of Hepatology, Wakayama Rosai Hospital, Wakayama, Japan., Fukumoto T; Department of Surgery, Division of Hepato-Biliary-Pancreatic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan., Hiasa Y; Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Japan., Kudo M; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka, Japan., Kumada T; Faculty of Nursing, Gifu Kyoritsu University, Ogaki, Japan.; Department of Epidemiology, Infectious Disease Control, and Prevention, Hiroshima University Institute of Biomedical and Health Sciences, Hiroshima, Japan.
Corporate Authors: RELPEC Group, HCC 48 Group
Source: Liver cancer [Liver Cancer] 2026 Apr 02. Date of Electronic Publication: 2026 Apr 02.
Publication Type: Journal Article
Journal Info: Publisher: S. Karger Country of Publication: Switzerland NLM ID: 101597993 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2235-1795 (Print) Linking ISSN: 16645553 NLM ISO Abbreviation: Liver Cancer
Database: MEDLINE Ultimate
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  Data: Real-World Comparison of First-Line Atezolizumab plus Bevacizumab and Durvalumab plus Tremelimumab for Unresectable Hepatocellular Carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Hiraoka+A%22">Hiraoka A</searchLink>; Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama, Japan.<br /><searchLink fieldCode="AU" term="%22Tada+T%22">Tada T</searchLink>; Department of Internal Medicine, Japanese Red Cross Society Himeji Hospital, Himeji, Japan.; Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Hirooka+M%22">Hirooka M</searchLink>; Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Japan.<br /><searchLink fieldCode="AU" term="%22Kariyama+K%22">Kariyama K</searchLink>; Department of Gastroenterology, Okayama City Hospital, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Tani+J%22">Tani J</searchLink>; Department of Gastroenterology and Neurology, Kagawa University, Takamatsu, Japan.<br /><searchLink fieldCode="AU" term="%22Atsukawa+M%22">Atsukawa M</searchLink>; 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Department of Gastroenterology, NHO Takasaki General Medical Center, Takasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Kosaka+H%22">Kosaka H</searchLink>; Department of Hepatobiliary Surgery, Kansai Medical University, Hirakata, Japan.<br /><searchLink fieldCode="AU" term="%22Matono+T%22">Matono T</searchLink>; Department of Gastroenterology, Harima Himeji General Medical Center, Himeji, Japan.<br /><searchLink fieldCode="AU" term="%22Kuroda+H%22">Kuroda H</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Iwate Medical University School of Medicine, Morioka, Japan.<br /><searchLink fieldCode="AU" term="%22Yata+Y%22">Yata Y</searchLink>; Department of Gastroenterology, Hanwa Memorial Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Nishikawa+H%22">Nishikawa H</searchLink>; Department of Gastroenterology, Osaka Medical and Pharmaceutical University, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Imai+M%22">Imai M</searchLink>; 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Department of Gastroenterology, Hyogo Medical University, Nishinomiya, Japan.<br /><searchLink fieldCode="AU" term="%22Matsui+K%22">Matsui K</searchLink>; Department of Hepatobiliary Surgery, Kansai Medical University, Hirakata, Japan.<br /><searchLink fieldCode="AU" term="%22Kaibori+M%22">Kaibori M</searchLink>; Department of Hepatobiliary Surgery, Kansai Medical University, Hirakata, Japan.<br /><searchLink fieldCode="AU" term="%22Okamura+J%22">Okamura J</searchLink>; Department of Hepatology, Wakayama Rosai Hospital, Wakayama, Japan.<br /><searchLink fieldCode="AU" term="%22Fukumoto+T%22">Fukumoto T</searchLink>; Department of Surgery, Division of Hepato-Biliary-Pancreatic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Hiasa+Y%22">Hiasa Y</searchLink>; Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Japan.<br /><searchLink fieldCode="AU" term="%22Kudo+M%22">Kudo M</searchLink>; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Kumada+T%22">Kumada T</searchLink>; Faculty of Nursing, Gifu Kyoritsu University, Ogaki, Japan.; Department of Epidemiology, Infectious Disease Control, and Prevention, Hiroshima University Institute of Biomedical and Health Sciences, Hiroshima, Japan.
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            NameFull: Fukumoto T
      – PersonEntity:
          Name:
            NameFull: Hiasa Y
      – PersonEntity:
          Name:
            NameFull: Kudo M
      – PersonEntity:
          Name:
            NameFull: Kumada T
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 02
              M: 04
              Text: 2026 Apr 02
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-print
              Value: 2235-1795
          Titles:
            – TitleFull: Liver cancer
              Type: main
ResultId 1