MND1 reduces breast cancer chemosensitivity by promoting RAD51-mediated homologous recombination repair.

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Title: MND1 reduces breast cancer chemosensitivity by promoting RAD51-mediated homologous recombination repair.
Authors: Yue HR; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.; Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China., Yu ZH; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.; Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China., Zhao HM; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.; Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China., Hai LY; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.; Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China., Liu WB; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.; Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China., Liu XF; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.; Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China., Chen ZH; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.; Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China., Yu Y; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China. yuyue@tmu.edu.cn.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China. yuyue@tmu.edu.cn.; Tianjin's Clinical Research Center for Cancer, Tianjin, China. yuyue@tmu.edu.cn.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China. yuyue@tmu.edu.cn., Ge J; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China. gejie1980@tmu.edu.cn.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China. gejie1980@tmu.edu.cn.; Tianjin's Clinical Research Center for Cancer, Tianjin, China. gejie1980@tmu.edu.cn.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China. gejie1980@tmu.edu.cn., Wang X; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China. wangxin@tjmuch.com.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China. wangxin@tjmuch.com.; Tianjin's Clinical Research Center for Cancer, Tianjin, China. wangxin@tjmuch.com.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China. wangxin@tjmuch.com.
Source: Cell death & disease [Cell Death Dis] 2026 Jun 03. Date of Electronic Publication: 2026 Jun 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: MND1 reduces breast cancer chemosensitivity by promoting RAD51-mediated homologous recombination repair.
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  Data: <searchLink fieldCode="AU" term="%22Yue+HR%22">Yue HR</searchLink>; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.; Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Yu+ZH%22">Yu ZH</searchLink>; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.; Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Zhao+HM%22">Zhao HM</searchLink>; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.; Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Hai+LY%22">Hai LY</searchLink>; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.; Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Liu+WB%22">Liu WB</searchLink>; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.; Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Liu+XF%22">Liu XF</searchLink>; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.; Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Chen+ZH%22">Chen ZH</searchLink>; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.; Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Yu+Y%22">Yu Y</searchLink>; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China. yuyue@tmu.edu.cn.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China. yuyue@tmu.edu.cn.; Tianjin's Clinical Research Center for Cancer, Tianjin, China. yuyue@tmu.edu.cn.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China. yuyue@tmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Ge+J%22">Ge J</searchLink>; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China. gejie1980@tmu.edu.cn.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China. gejie1980@tmu.edu.cn.; Tianjin's Clinical Research Center for Cancer, Tianjin, China. gejie1980@tmu.edu.cn.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China. gejie1980@tmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China. wangxin@tjmuch.com.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China. wangxin@tjmuch.com.; Tianjin's Clinical Research Center for Cancer, Tianjin, China. wangxin@tjmuch.com.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China. wangxin@tjmuch.com.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41419-026-08912-w
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        Text: English
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      – TitleFull: MND1 reduces breast cancer chemosensitivity by promoting RAD51-mediated homologous recombination repair.
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              Text: 2026 Jun 03
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