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Longitudinal evaluation of serial ctDNA kinetics using joint modeling in patients with metastatic breast cancer.

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Title: Longitudinal evaluation of serial ctDNA kinetics using joint modeling in patients with metastatic breast cancer.
Authors: Pretz C; Guardant Health, Inc., Redwood City, CA, USA. cpretz@guardanthealth.com., Fuentes-Antrás J; NEXT Oncology, Hospital Universitario Quirónsalud Madrid, Madrid, Spain., Main S; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Dou A; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre, Toronto, ON, Canada., Shah E; Cancer Genomics Program, Princess Margaret Cancer Centre, Toronto, ON, Canada., Van de Laar E; Cancer Genomics Program, Princess Margaret Cancer Centre, Toronto, ON, Canada., Weipert CM; Guardant Health, Inc., Redwood City, CA, USA., Lin B; Guardant Health, Inc., Redwood City, CA, USA., Das A; Guardant Health, Inc., Redwood City, CA, USA., Amir E; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre, Toronto, ON, Canada., Nadler MB; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre, Toronto, ON, Canada., Yu C; Cancer Genomics Program, Princess Margaret Cancer Centre, Toronto, ON, Canada., Berman HK; Department of Pathology and Laboratory Medicine, University Health Network, Toronto, Canada., Siu LL; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre, Toronto, ON, Canada., Bedard PL; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre, Toronto, ON, Canada., Elliott MJ; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre, Toronto, ON, Canada.; Division of Medical Oncology, Yale Cancer Center, New Haven, CT, USA., Cescon DW; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre, Toronto, ON, Canada.
Source: NPJ precision oncology [NPJ Precis Oncol] 2026 Jun 03. Date of Electronic Publication: 2026 Jun 03.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Pretz+C%22">Pretz C</searchLink>; Guardant Health, Inc., Redwood City, CA, USA. cpretz@guardanthealth.com.<br /><searchLink fieldCode="AU" term="%22Fuentes-Antrás+J%22">Fuentes-Antrás J</searchLink>; NEXT Oncology, Hospital Universitario Quirónsalud Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Main+S%22">Main S</searchLink>; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Dou+A%22">Dou A</searchLink>; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Shah+E%22">Shah E</searchLink>; Cancer Genomics Program, Princess Margaret Cancer Centre, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Van+de+Laar+E%22">Van de Laar E</searchLink>; Cancer Genomics Program, Princess Margaret Cancer Centre, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Weipert+CM%22">Weipert CM</searchLink>; Guardant Health, Inc., Redwood City, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lin+B%22">Lin B</searchLink>; Guardant Health, Inc., Redwood City, CA, USA.<br /><searchLink fieldCode="AU" term="%22Das+A%22">Das A</searchLink>; Guardant Health, Inc., Redwood City, CA, USA.<br /><searchLink fieldCode="AU" term="%22Amir+E%22">Amir E</searchLink>; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Nadler+MB%22">Nadler MB</searchLink>; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Yu+C%22">Yu C</searchLink>; Cancer Genomics Program, Princess Margaret Cancer Centre, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Berman+HK%22">Berman HK</searchLink>; Department of Pathology and Laboratory Medicine, University Health Network, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Siu+LL%22">Siu LL</searchLink>; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Bedard+PL%22">Bedard PL</searchLink>; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Elliott+MJ%22">Elliott MJ</searchLink>; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre, Toronto, ON, Canada.; Division of Medical Oncology, Yale Cancer Center, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Cescon+DW%22">Cescon DW</searchLink>; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre, Toronto, ON, Canada.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101708166 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2397-768X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222397768X%22">2397768X </searchLink><i>NLM ISO Abbreviation: </i>NPJ Precis Oncol
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              Text: 2026 Jun 03
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