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A human telomerase reverse transcriptase-derived peptide GV1001 rescues neurodegeneration in a mouse model of Alzheimer disease.

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Title: A human telomerase reverse transcriptase-derived peptide GV1001 rescues neurodegeneration in a mouse model of Alzheimer disease.
Authors: Lee Y; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Republic of Korea., Nam H; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Republic of Korea., Lee JW; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Republic of Korea., Ko YJ; Department of Physiology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea., Kim EJ; Emotion, Cognitive & Behavior Research Group, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea., Ha S; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Republic of Korea., Kim N; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Republic of Korea., Koo JW; Emotion, Cognitive & Behavior Research Group, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea., Son T; Korea Brain Bank, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea. taekwon@kbri.re.kr., Kim S; Teloid Inc., Los Angeles, CA, USA. chiron@gemvax.com., Yu SW; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Republic of Korea. yusw@dgist.ac.kr.
Source: Experimental & molecular medicine [Exp Mol Med] 2026 Jun 03. Date of Electronic Publication: 2026 Jun 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9607880 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2092-6413 (Electronic) Linking ISSN: 12263613 NLM ISO Abbreviation: Exp Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A human telomerase reverse transcriptase-derived peptide GV1001 rescues neurodegeneration in a mouse model of Alzheimer disease.
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  Data: <searchLink fieldCode="AU" term="%22Lee+Y%22">Lee Y</searchLink>; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Nam+H%22">Nam H</searchLink>; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JW%22">Lee JW</searchLink>; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ko+YJ%22">Ko YJ</searchLink>; Department of Physiology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+EJ%22">Kim EJ</searchLink>; Emotion, Cognitive & Behavior Research Group, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ha+S%22">Ha S</searchLink>; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+N%22">Kim N</searchLink>; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Koo+JW%22">Koo JW</searchLink>; Emotion, Cognitive & Behavior Research Group, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Son+T%22">Son T</searchLink>; Korea Brain Bank, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea. taekwon@kbri.re.kr.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Teloid Inc., Los Angeles, CA, USA. chiron@gemvax.com.<br /><searchLink fieldCode="AU" term="%22Yu+SW%22">Yu SW</searchLink>; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Republic of Korea. yusw@dgist.ac.kr.
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  Data: <searchLink fieldCode="JN" term="%229607880%22">Experimental & molecular medicine</searchLink> [Exp Mol Med] 2026 Jun 03. <i>Date of Electronic Publication: </i>2026 Jun 03.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9607880 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2092-6413 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2212263613%22">12263613 </searchLink><i>NLM ISO Abbreviation: </i>Exp Mol Med <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s12276-026-01729-9
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        Text: English
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      – TitleFull: A human telomerase reverse transcriptase-derived peptide GV1001 rescues neurodegeneration in a mouse model of Alzheimer disease.
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            – D: 03
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              Text: 2026 Jun 03
              Type: published
              Y: 2026
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