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Commensal-derived acetylcholine enhances mucosal immune education.

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Title: Commensal-derived acetylcholine enhances mucosal immune education.
Authors: Song D; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA., Duncan-Lowey B; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA., Khetrapal V; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA., Hamchand R; Institute of Biomolecular Design & Discovery and Department of Chemistry, Yale University, West Haven and New Haven, CT, USA., Deng T; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA., Brown H; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA., Wu A; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA., Martin AL; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA., Bauer KM; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA., Zhao Y; Institute of Biomolecular Design & Discovery and Department of Chemistry, Yale University, West Haven and New Haven, CT, USA., Nguyen MT; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA., Sonnert ND; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA., Leopold SR; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA., Wu Q; Institute of Biomolecular Design & Discovery and Department of Chemistry, Yale University, West Haven and New Haven, CT, USA.; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA., Crawford JM; Institute of Biomolecular Design & Discovery and Department of Chemistry, Yale University, West Haven and New Haven, CT, USA., Palm NW; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA. noah.palm@yale.edu.
Source: Nature [Nature] 2026 Jun 03. Date of Electronic Publication: 2026 Jun 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Song+D%22">Song D</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Duncan-Lowey+B%22">Duncan-Lowey B</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Khetrapal+V%22">Khetrapal V</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Hamchand+R%22">Hamchand R</searchLink>; Institute of Biomolecular Design & Discovery and Department of Chemistry, Yale University, West Haven and New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Deng+T%22">Deng T</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Brown+H%22">Brown H</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Wu+A%22">Wu A</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Martin+AL%22">Martin AL</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Bauer+KM%22">Bauer KM</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+Y%22">Zhao Y</searchLink>; Institute of Biomolecular Design & Discovery and Department of Chemistry, Yale University, West Haven and New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+MT%22">Nguyen MT</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Sonnert+ND%22">Sonnert ND</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Leopold+SR%22">Leopold SR</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Wu+Q%22">Wu Q</searchLink>; Institute of Biomolecular Design & Discovery and Department of Chemistry, Yale University, West Haven and New Haven, CT, USA.; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Crawford+JM%22">Crawford JM</searchLink>; Institute of Biomolecular Design & Discovery and Department of Chemistry, Yale University, West Haven and New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Palm+NW%22">Palm NW</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA. noah.palm@yale.edu.
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