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Single-cell multi-omic atlas and morphogen screening informs midbrain and hindbrain organoid engineering.

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Title: Single-cell multi-omic atlas and morphogen screening informs midbrain and hindbrain organoid engineering.
Authors: Azbukina N; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., He Z; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Lin HC; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Santel M; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Kashanian B; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Maynard A; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Török T; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Okamoto R; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Nikolova MT; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Seimiya M; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Kanton S; Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany., Brösamle V; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Holtackers R; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Camp JG; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland. jarrettgrayson.camp@unibas.ch.; Biozentrum, University of Basel, Basel, Switzerland. jarrettgrayson.camp@unibas.ch., Treutlein B; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland. barbara.treutlein@bsse.ethz.ch.
Source: Nature neuroscience [Nat Neurosci] 2026 Jun 03. Date of Electronic Publication: 2026 Jun 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Single-cell multi-omic atlas and morphogen screening informs midbrain and hindbrain organoid engineering.
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  Data: <searchLink fieldCode="AU" term="%22Azbukina+N%22">Azbukina N</searchLink>; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22He+Z%22">He Z</searchLink>; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lin+HC%22">Lin HC</searchLink>; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Santel+M%22">Santel M</searchLink>; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kashanian+B%22">Kashanian B</searchLink>; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Maynard+A%22">Maynard A</searchLink>; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Török+T%22">Török T</searchLink>; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Okamoto+R%22">Okamoto R</searchLink>; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Nikolova+MT%22">Nikolova MT</searchLink>; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Seimiya+M%22">Seimiya M</searchLink>; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kanton+S%22">Kanton S</searchLink>; Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Brösamle+V%22">Brösamle V</searchLink>; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Holtackers+R%22">Holtackers R</searchLink>; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Camp+JG%22">Camp JG</searchLink>; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland. jarrettgrayson.camp@unibas.ch.; Biozentrum, University of Basel, Basel, Switzerland. jarrettgrayson.camp@unibas.ch.<br /><searchLink fieldCode="AU" term="%22Treutlein+B%22">Treutlein B</searchLink>; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland. barbara.treutlein@bsse.ethz.ch.
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  Data: <searchLink fieldCode="JN" term="%229809671%22">Nature neuroscience</searchLink> [Nat Neurosci] 2026 Jun 03. <i>Date of Electronic Publication: </i>2026 Jun 03.
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