Gabapentin to achieve HIV viral load suppression in people with risky drinking in Mbarara, Uganda: study protocol for a randomized, double-blinded, placebo-controlled trial (GRAIL).

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Title: Gabapentin to achieve HIV viral load suppression in people with risky drinking in Mbarara, Uganda: study protocol for a randomized, double-blinded, placebo-controlled trial (GRAIL).
Authors: Truong V; Department of Medicine, Section of General Internal Medicine, Clinical Addiction Research and Education (CARE) Unit, Boston University Chobanian and Avedisian School of Medicine, Boston Medical Center, Boston, MA, USA., Kekibiina A; Mbarara University of Science and Technology, Mbarara, Uganda., Muyindike WR; Mbarara University of Science and Technology, Mbarara, Uganda., Gnatienko N; Department of Medicine, Section of General Internal Medicine, Clinical Addiction Research and Education (CARE) Unit, Boston University Chobanian and Avedisian School of Medicine, Boston Medical Center, Boston, MA, USA., Tsui JI; Department of Medicine, Division of General Internal Medicine, School of Medicine/Harborview Medical Center, University of Washington, Seattle, WA, USA., Emenyonu NI; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Cheng DM; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; Biostatistics and Epidemiology Data Analytics Center for Health Data Science (CHDS), Boston University School of Public Health, Boston, MA, USA., Hahn JA; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Allison O; Department of Medicine, Section of General Internal Medicine, Clinical Addiction Research and Education (CARE) Unit, Boston University Chobanian and Avedisian School of Medicine, Boston Medical Center, Boston, MA, USA., Bullard MJ; Biostatistics and Epidemiology Data Analytics Center for Health Data Science (CHDS), Boston University School of Public Health, Boston, MA, USA., Lunze K; Department of Medicine, Section of General Internal Medicine, Clinical Addiction Research and Education (CARE) Unit, Boston University Chobanian and Avedisian School of Medicine, Boston Medical Center, Boston, MA, USA., Samet JH; Department of Medicine, Section of General Internal Medicine, Clinical Addiction Research and Education (CARE) Unit, Boston University Chobanian and Avedisian School of Medicine, Boston Medical Center, Boston, MA, USA. jsamet@bu.edu.; Department of Community Health Sciences, Boston University School of Public Health, Boston, MA, USA. jsamet@bu.edu.
Source: Trials [Trials] 2026 Jun 03; Vol. 27 (1). Date of Electronic Publication: 2026 Jun 03.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Gabapentin to achieve HIV viral load suppression in people with risky drinking in Mbarara, Uganda: study protocol for a randomized, double-blinded, placebo-controlled trial (GRAIL).
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  Data: <searchLink fieldCode="AU" term="%22Truong+V%22">Truong V</searchLink>; Department of Medicine, Section of General Internal Medicine, Clinical Addiction Research and Education (CARE) Unit, Boston University Chobanian and Avedisian School of Medicine, Boston Medical Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kekibiina+A%22">Kekibiina A</searchLink>; Mbarara University of Science and Technology, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Muyindike+WR%22">Muyindike WR</searchLink>; Mbarara University of Science and Technology, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Gnatienko+N%22">Gnatienko N</searchLink>; Department of Medicine, Section of General Internal Medicine, Clinical Addiction Research and Education (CARE) Unit, Boston University Chobanian and Avedisian School of Medicine, Boston Medical Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Tsui+JI%22">Tsui JI</searchLink>; Department of Medicine, Division of General Internal Medicine, School of Medicine/Harborview Medical Center, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Emenyonu+NI%22">Emenyonu NI</searchLink>; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cheng+DM%22">Cheng DM</searchLink>; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; Biostatistics and Epidemiology Data Analytics Center for Health Data Science (CHDS), Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hahn+JA%22">Hahn JA</searchLink>; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Allison+O%22">Allison O</searchLink>; Department of Medicine, Section of General Internal Medicine, Clinical Addiction Research and Education (CARE) Unit, Boston University Chobanian and Avedisian School of Medicine, Boston Medical Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bullard+MJ%22">Bullard MJ</searchLink>; Biostatistics and Epidemiology Data Analytics Center for Health Data Science (CHDS), Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lunze+K%22">Lunze K</searchLink>; Department of Medicine, Section of General Internal Medicine, Clinical Addiction Research and Education (CARE) Unit, Boston University Chobanian and Avedisian School of Medicine, Boston Medical Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Samet+JH%22">Samet JH</searchLink>; Department of Medicine, Section of General Internal Medicine, Clinical Addiction Research and Education (CARE) Unit, Boston University Chobanian and Avedisian School of Medicine, Boston Medical Center, Boston, MA, USA. jsamet@bu.edu.; Department of Community Health Sciences, Boston University School of Public Health, Boston, MA, USA. jsamet@bu.edu.
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              Text: 2026 Jun 03
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