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Opportunistic CT Attenuation Biomarkers of Anemia Are Associated With Impaired Myocardial Flow Reserve and Cardiovascular Outcomes.

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Title: Opportunistic CT Attenuation Biomarkers of Anemia Are Associated With Impaired Myocardial Flow Reserve and Cardiovascular Outcomes.
Authors: Miller RJH; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.; Department of Cardiac Sciences, University of Calgary, Calgary Alberta, Canada., Shanbhag A; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.; Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, USA., Yi J; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Kwiecinski J; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.; Department of Interventional Cardiology and Angiology, Institute of Cardiology, Warsaw, Poland., Kavanagh P; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Ramirez G; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Lemley M; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Kamagate A; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Slipczuk L; Cardiology Division, Montefiore Health System/Albert Einstein College of Medicine, NY, USA., Travin MI; Department of Radiology (Nuclear Medicine), Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USA., Alexanderson E; Faculty of Medicine, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico., Carvajal-Juarez I; Faculty of Medicine, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico., Packard RRS; Division of Cardiology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Al-Mallah M; Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Academic Institute, Houston, TX, USA., Einstein AJ; Division of Cardiology, Department of Medicine, and Department of Radiology, Columbia University Irving Medical Center and New York-Presbyterian Hospital, New York, USA., Acampa W; Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy., Knight S; Intermountain Medical Center Heart Institute, Intermountain Healthcare, Murray, UT, USA.; Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA., Le VT; Intermountain Medical Center Heart Institute, Intermountain Healthcare, Murray, UT, USA., Mason S; Intermountain Medical Center Heart Institute, Intermountain Healthcare, Murray, UT, USA., Wopperer S; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Chareonthaitawee P; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Rosamond TL; Department of Cardiovascular Medicine, The University of Kansas Medical Center, Kansas City, KS, USA., DeKemp RA; Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, ON, Canada., Buechel RR; Cardiovascular Imaging Program, Departments of Radiology and Medicine; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology; and Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Berman DS; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Dey D; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Di Carli MF; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.; Department of Cardiac Sciences, University of Calgary, Calgary Alberta, Canada.; Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, USA.; Department of Interventional Cardiology and Angiology, Institute of Cardiology, Warsaw, Poland.; Cardiology Division, Montefiore Health System/Albert Einstein College of Medicine, NY, USA.; Department of Radiology (Nuclear Medicine), Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USA.; Faculty of Medicine, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico.; Division of Cardiology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.; Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Academic Institute, Houston, TX, USA.; Division of Cardiology, Department of Medicine, and Department of Radiology, Columbia University Irving Medical Center and New York-Presbyterian Hospital, New York, USA.; Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.; Intermountain Medical Center Heart Institute, Intermountain Healthcare, Murray, UT, USA.; Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA.; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Cardiovascular Medicine, The University of Kansas Medical Center, Kansas City, KS, USA.; Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, ON, Canada.; Department of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Zurich, Switzerland.; Cardiovascular Imaging Program, Departments of Radiology and Medicine; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology; and Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Slomka PJ; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2026 May 19. Date of Electronic Publication: 2026 May 19.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Opportunistic CT Attenuation Biomarkers of Anemia Are Associated With Impaired Myocardial Flow Reserve and Cardiovascular Outcomes.
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  Data: <searchLink fieldCode="AU" term="%22Miller+RJH%22">Miller RJH</searchLink>; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.; Department of Cardiac Sciences, University of Calgary, Calgary Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Shanbhag+A%22">Shanbhag A</searchLink>; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.; Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yi+J%22">Yi J</searchLink>; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Kwiecinski+J%22">Kwiecinski J</searchLink>; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.; Department of Interventional Cardiology and Angiology, Institute of Cardiology, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Kavanagh+P%22">Kavanagh P</searchLink>; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Ramirez+G%22">Ramirez G</searchLink>; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Lemley+M%22">Lemley M</searchLink>; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Kamagate+A%22">Kamagate A</searchLink>; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Slipczuk+L%22">Slipczuk L</searchLink>; Cardiology Division, Montefiore Health System/Albert Einstein College of Medicine, NY, USA.<br /><searchLink fieldCode="AU" term="%22Travin+MI%22">Travin MI</searchLink>; Department of Radiology (Nuclear Medicine), Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USA.<br /><searchLink fieldCode="AU" term="%22Alexanderson+E%22">Alexanderson E</searchLink>; Faculty of Medicine, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Carvajal-Juarez+I%22">Carvajal-Juarez I</searchLink>; Faculty of Medicine, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Packard+RRS%22">Packard RRS</searchLink>; Division of Cardiology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Al-Mallah+M%22">Al-Mallah M</searchLink>; Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Academic Institute, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Einstein+AJ%22">Einstein AJ</searchLink>; Division of Cardiology, Department of Medicine, and Department of Radiology, Columbia University Irving Medical Center and New York-Presbyterian Hospital, New York, USA.<br /><searchLink fieldCode="AU" term="%22Acampa+W%22">Acampa W</searchLink>; Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Knight+S%22">Knight S</searchLink>; Intermountain Medical Center Heart Institute, Intermountain Healthcare, Murray, UT, USA.; Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Le+VT%22">Le VT</searchLink>; Intermountain Medical Center Heart Institute, Intermountain Healthcare, Murray, UT, USA.<br /><searchLink fieldCode="AU" term="%22Mason+S%22">Mason S</searchLink>; Intermountain Medical Center Heart Institute, Intermountain Healthcare, Murray, UT, USA.<br /><searchLink fieldCode="AU" term="%22Wopperer+S%22">Wopperer S</searchLink>; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Chareonthaitawee+P%22">Chareonthaitawee P</searchLink>; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Rosamond+TL%22">Rosamond TL</searchLink>; Department of Cardiovascular Medicine, The University of Kansas Medical Center, Kansas City, KS, USA.<br /><searchLink fieldCode="AU" term="%22DeKemp+RA%22">DeKemp RA</searchLink>; Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Buechel+RR%22">Buechel RR</searchLink>; Cardiovascular Imaging Program, Departments of Radiology and Medicine; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology; and Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Berman+DS%22">Berman DS</searchLink>; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Dey+D%22">Dey D</searchLink>; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Di+Carli+MF%22">Di Carli MF</searchLink>; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.; Department of Cardiac Sciences, University of Calgary, Calgary Alberta, Canada.; Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, USA.; Department of Interventional Cardiology and Angiology, Institute of Cardiology, Warsaw, Poland.; Cardiology Division, Montefiore Health System/Albert Einstein College of Medicine, NY, USA.; Department of Radiology (Nuclear Medicine), Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USA.; Faculty of Medicine, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico.; Division of Cardiology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.; Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Academic Institute, Houston, TX, USA.; Division of Cardiology, Department of Medicine, and Department of Radiology, Columbia University Irving Medical Center and New York-Presbyterian Hospital, New York, USA.; Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.; Intermountain Medical Center Heart Institute, Intermountain Healthcare, Murray, UT, USA.; Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA.; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Cardiovascular Medicine, The University of Kansas Medical Center, Kansas City, KS, USA.; Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, ON, Canada.; Department of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Zurich, Switzerland.; Cardiovascular Imaging Program, Departments of Radiology and Medicine; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology; and Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Slomka+PJ%22">Slomka PJ</searchLink>; Artificial Intelligence in Medicine Research Center, Departments of Biomedical Sciences, Medicine, and Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
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