View in EDS

CNS-selective plasma p-tau217 accurately captures Alzheimer's disease pathology and progression.

Saved in:
Bibliographic Details
Title: CNS-selective plasma p-tau217 accurately captures Alzheimer's disease pathology and progression.
Authors: Zeng X; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Biofluid Biomarker Laboratory, Western Psychiatric Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA., Farinas MF; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Biofluid Biomarker Laboratory, Western Psychiatric Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA., Nafash MN; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Biofluid Biomarker Laboratory, Western Psychiatric Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA., Smirnov DS; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Biofluid Biomarker Laboratory, Western Psychiatric Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.; Department of Pathology, Mass General Brigham, Boston, MA 02114., Lopresti BJ; Department of Radiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Matan C; Department of Radiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Tudorascu DL; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA., Berman SB; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.; Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Sweet RA; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA., Shaaban CE; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.; Department of Health Promotion and Development, School of Nursing, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA., Snitz BE; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.; Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Kofler JK; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.; Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Nadkarni NK; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.; Division of Geriatric Medicine, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Aizenstein HJ; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA., Ikonomovic MD; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.; Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Geriatric Research Education and Clinical Center, VA Pittsburgh HS, Pittsburgh, PA, USA., Pascoal TA; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.; Department of Radiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Villemagne VL; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA., Kamboh MI; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.; Department of Human Genetics, School of Public Health, University of Pittsburgh, Pittsburgh, PA, 15261, USA., Cohen AD; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA., Lopez OL; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.; Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Karikari TK; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Biofluid Biomarker Laboratory, Western Psychiatric Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2026 May 21. Date of Electronic Publication: 2026 May 21.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42238423
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: CNS-selective plasma p-tau217 accurately captures Alzheimer's disease pathology and progression.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Zeng+X%22">Zeng X</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Biofluid Biomarker Laboratory, Western Psychiatric Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Farinas+MF%22">Farinas MF</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Biofluid Biomarker Laboratory, Western Psychiatric Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Nafash+MN%22">Nafash MN</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Biofluid Biomarker Laboratory, Western Psychiatric Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Smirnov+DS%22">Smirnov DS</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Biofluid Biomarker Laboratory, Western Psychiatric Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.; Department of Pathology, Mass General Brigham, Boston, MA 02114.<br /><searchLink fieldCode="AU" term="%22Lopresti+BJ%22">Lopresti BJ</searchLink>; Department of Radiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Matan+C%22">Matan C</searchLink>; Department of Radiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Tudorascu+DL%22">Tudorascu DL</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Berman+SB%22">Berman SB</searchLink>; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.; Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Sweet+RA%22">Sweet RA</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Shaaban+CE%22">Shaaban CE</searchLink>; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.; Department of Health Promotion and Development, School of Nursing, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Snitz+BE%22">Snitz BE</searchLink>; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.; Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Kofler+JK%22">Kofler JK</searchLink>; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.; Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Nadkarni+NK%22">Nadkarni NK</searchLink>; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.; Division of Geriatric Medicine, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Aizenstein+HJ%22">Aizenstein HJ</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Ikonomovic+MD%22">Ikonomovic MD</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.; Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Geriatric Research Education and Clinical Center, VA Pittsburgh HS, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Pascoal+TA%22">Pascoal TA</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.; Department of Radiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Villemagne+VL%22">Villemagne VL</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Kamboh+MI%22">Kamboh MI</searchLink>; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.; Department of Human Genetics, School of Public Health, University of Pittsburgh, Pittsburgh, PA, 15261, USA.<br /><searchLink fieldCode="AU" term="%22Cohen+AD%22">Cohen AD</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Lopez+OL%22">Lopez OL</searchLink>; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.; Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Karikari+TK%22">Karikari TK</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Biofluid Biomarker Laboratory, Western Psychiatric Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh PA 15213, USA.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101767986%22">MedRxiv : the preprint server for health sciences</searchLink> [medRxiv] 2026 May 21. <i>Date of Electronic Publication: </i>2026 May 21.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Preprint
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101767986 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>NLM ISO Abbreviation: </i>medRxiv <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42238423
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.64898/2026.05.18.26353208
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: CNS-selective plasma p-tau217 accurately captures Alzheimer's disease pathology and progression.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Zeng X
      – PersonEntity:
          Name:
            NameFull: Farinas MF
      – PersonEntity:
          Name:
            NameFull: Nafash MN
      – PersonEntity:
          Name:
            NameFull: Smirnov DS
      – PersonEntity:
          Name:
            NameFull: Lopresti BJ
      – PersonEntity:
          Name:
            NameFull: Matan C
      – PersonEntity:
          Name:
            NameFull: Tudorascu DL
      – PersonEntity:
          Name:
            NameFull: Berman SB
      – PersonEntity:
          Name:
            NameFull: Sweet RA
      – PersonEntity:
          Name:
            NameFull: Shaaban CE
      – PersonEntity:
          Name:
            NameFull: Snitz BE
      – PersonEntity:
          Name:
            NameFull: Kofler JK
      – PersonEntity:
          Name:
            NameFull: Nadkarni NK
      – PersonEntity:
          Name:
            NameFull: Aizenstein HJ
      – PersonEntity:
          Name:
            NameFull: Ikonomovic MD
      – PersonEntity:
          Name:
            NameFull: Pascoal TA
      – PersonEntity:
          Name:
            NameFull: Villemagne VL
      – PersonEntity:
          Name:
            NameFull: Kamboh MI
      – PersonEntity:
          Name:
            NameFull: Cohen AD
      – PersonEntity:
          Name:
            NameFull: Lopez OL
      – PersonEntity:
          Name:
            NameFull: Karikari TK
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 21
              M: 05
              Text: 2026 May 21
              Type: published
              Y: 2026
          Titles:
            – TitleFull: MedRxiv : the preprint server for health sciences
              Type: main
ResultId 1