A Model-Informed Early Prediction of Methotrexate-Induced Acute Kidney Injury in Pediatric Patients with Osteosarcoma Using Real-World Data: A Multi-center Pharmacokinetic Study.
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| Title: | A Model-Informed Early Prediction of Methotrexate-Induced Acute Kidney Injury in Pediatric Patients with Osteosarcoma Using Real-World Data: A Multi-center Pharmacokinetic Study. |
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| Authors: | Rega P; Department of Pharmaceutical Sciences, Faculty of Chemistry, Universidad de la República, Montevideo, Uruguay., Vallespin JM; Department of Pharmacy, Hospital Calvo Mackenna, Santiago de Chile, Chile., Aldaz A; Department of Pharmacy, Clinica Universidad de Navarra, Navarra, Spain., Pappas A; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Guido PC; Unit of Clinical Pharmacokinetics, Hospital de Pediatria JP Garrahan, Buenos Aires, Argentina., Azocar M; Department of Pharmacy, Hospital Calvo Mackenna, Santiago de Chile, Chile., Villarroel M; Oncology Service, Hospital Calvo Mackenna, Santiago de Chile, Chile., Pauley JL; Department of Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN, USA., Stewart CF; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Ibarra M; Department of Pharmaceutical Sciences, Faculty of Chemistry, Universidad de la República, Montevideo, Uruguay., Schaiquevich P; Unit of Innovative Treatments, Hospital de Pediatria JP Garrahan, Combate de los Pozos 1881, CP1245, CABA, Buenos Aires, Argentina. paulas@conicet.gov.ar.; Consejo Nacional de Investigaciones Científicas y Técnicas, CONICET, Buenos Aires, Argentina. paulas@conicet.gov.ar. |
| Source: | Clinical pharmacokinetics [Clin Pharmacokinet] 2026 Jun 04. Date of Electronic Publication: 2026 Jun 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926 (Electronic) Linking ISSN: 03125963 NLM ISO Abbreviation: Clin Pharmacokinet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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