First-in-human ex-vivo validation of carbonic anhydrase IX-PET for high-risk renal cancer (CAT-VHL - PNRR-POC-2023-12377493).

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Title: First-in-human ex-vivo validation of carbonic anhydrase IX-PET for high-risk renal cancer (CAT-VHL - PNRR-POC-2023-12377493).
Authors: Larcher A; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy., Gelardi F; Department of Nuclear Medicine, IRCCS Ospedale San Raffaele, Milan, Italy., Antunovic L; Department of Nuclear Medicine, IRCCS Ospedale San Raffaele, Milan, Italy., Savi A; Department of Nuclear Medicine, IRCCS Ospedale San Raffaele, Milan, Italy., Olivieri M; Department of Nuclear Medicine, IRCCS Ospedale San Raffaele, Milan, Italy., Rainone P; Department of Nuclear Medicine, IRCCS Ospedale San Raffaele, Milan, Italy.; Institute of Molecular Bioimaging and Physiology-IBFM, CNR, Segrate, Italy., Sollini M; Department of Nuclear Medicine, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Moresco RM; Department of Nuclear Medicine, IRCCS Ospedale San Raffaele, Milan, Italy.; Institute of Molecular Bioimaging and Physiology-IBFM, CNR, Segrate, Italy.; Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy., Re C; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Cei F; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Belladelli F; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Musso G; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Salerno L; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., De Cobelli F; Vita-Salute San Raffaele University, Milan, Italy.; Department of Radiology, IRCCS Ospedale San Raffaele, Milan, Italy., Tenace N; Vita-Salute San Raffaele University, Milan, Italy.; Department of Pathology, IRCCS Ospedale San Raffaele, Milan, Italy., Ponzoni M; Vita-Salute San Raffaele University, Milan, Italy.; Department of Pathology, IRCCS Ospedale San Raffaele, Milan, Italy., Cigliola A; Department of Oncology, IRCCS Ospedale San Raffaele, Milan, Italy., Verze P; Department of Urology, AOU San Giovanni di Dio Ruggi d'Aragona, Salerno, Italy.; Università degli Studi di Salerno, Salerno, Italy., Bertini R; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy., Briganti A; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Montorsi F; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Capitanio U; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy., Salonia A; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Chiti A; Department of Nuclear Medicine, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.
Source: Theranostics [Theranostics] 2026 May 18; Vol. 16 (12), pp. 6980-6987. Date of Electronic Publication: 2026 May 18 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101552395 Publication Model: eCollection Cited Medium: Internet ISSN: 1838-7640 (Electronic) Linking ISSN: 18387640 NLM ISO Abbreviation: Theranostics Subsets: MEDLINE
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  Data: First-in-human ex-vivo validation of carbonic anhydrase IX-PET for high-risk renal cancer (CAT-VHL - PNRR-POC-2023-12377493).
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  Data: <searchLink fieldCode="AU" term="%22Larcher+A%22">Larcher A</searchLink>; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gelardi+F%22">Gelardi F</searchLink>; Department of Nuclear Medicine, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Antunovic+L%22">Antunovic L</searchLink>; Department of Nuclear Medicine, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Savi+A%22">Savi A</searchLink>; Department of Nuclear Medicine, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Olivieri+M%22">Olivieri M</searchLink>; Department of Nuclear Medicine, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Rainone+P%22">Rainone P</searchLink>; Department of Nuclear Medicine, IRCCS Ospedale San Raffaele, Milan, Italy.; Institute of Molecular Bioimaging and Physiology-IBFM, CNR, Segrate, Italy.<br /><searchLink fieldCode="AU" term="%22Sollini+M%22">Sollini M</searchLink>; Department of Nuclear Medicine, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Moresco+RM%22">Moresco RM</searchLink>; Department of Nuclear Medicine, IRCCS Ospedale San Raffaele, Milan, Italy.; Institute of Molecular Bioimaging and Physiology-IBFM, CNR, Segrate, Italy.; Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22Re+C%22">Re C</searchLink>; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cei+F%22">Cei F</searchLink>; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Belladelli+F%22">Belladelli F</searchLink>; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Musso+G%22">Musso G</searchLink>; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Salerno+L%22">Salerno L</searchLink>; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22De+Cobelli+F%22">De Cobelli F</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.; Department of Radiology, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Tenace+N%22">Tenace N</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.; Department of Pathology, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ponzoni+M%22">Ponzoni M</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.; Department of Pathology, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cigliola+A%22">Cigliola A</searchLink>; Department of Oncology, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Verze+P%22">Verze P</searchLink>; Department of Urology, AOU San Giovanni di Dio Ruggi d'Aragona, Salerno, Italy.; Università degli Studi di Salerno, Salerno, Italy.<br /><searchLink fieldCode="AU" term="%22Bertini+R%22">Bertini R</searchLink>; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Briganti+A%22">Briganti A</searchLink>; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Montorsi+F%22">Montorsi F</searchLink>; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Capitanio+U%22">Capitanio U</searchLink>; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Salonia+A%22">Salonia A</searchLink>; Department of Urology, Division of Oncology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.; VHL Program, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Chiti+A%22">Chiti A</searchLink>; Department of Nuclear Medicine, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.
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  Data: <searchLink fieldCode="JN" term="%22101552395%22">Theranostics</searchLink> [Theranostics] 2026 May 18; Vol. 16 (12), pp. 6980-6987. <i>Date of Electronic Publication: </i>2026 May 18 (<i>Print Publication: </i>2026).
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