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Pharmacokinetics of xylazine and fentanyl in patients presenting to the emergency department after non-fatal opioid overdose.

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Title: Pharmacokinetics of xylazine and fentanyl in patients presenting to the emergency department after non-fatal opioid overdose.
Authors: Krotulski AJ; Center for Forensic Science Research and Education, Fredric Rieders Family Foundation, 206 Welsh Road, Horsham, PA 19044, USA; College of Life Sciences, Thomas Jefferson University, 1020 Locust St, Philadelphia, PA 19107, USA. Electronic address: alex.krotulski@cfsre.org., Baumann MH; Designer Drug Research Unit, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 333 Cassell Drive, Suite 4400, Baltimore, MD 21224, USA., Chapman BP; Department of Emergency Medicine, University of Massachusetts Chan Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA., Martinez PME; Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, 1468 Madison Avenue, New York, NY 10029, USA., Broach JP; Department of Emergency Medicine, University of Massachusetts Chan Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA., Nguyen J; Designer Drug Research Unit, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 333 Cassell Drive, Suite 4400, Baltimore, MD 21224, USA., Olabisi D; Department of Emergency Medicine, University of Massachusetts Chan Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA., Polackal J; Department of Emergency Medicine, University of Massachusetts Chan Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA., Walton SE; Center for Forensic Science Research and Education, Fredric Rieders Family Foundation, 206 Welsh Road, Horsham, PA 19044, USA., Stang BN; Center for Forensic Science Research and Education, Fredric Rieders Family Foundation, 206 Welsh Road, Horsham, PA 19044, USA., Reyes AG; Center for Forensic Science Research and Education, Fredric Rieders Family Foundation, 206 Welsh Road, Horsham, PA 19044, USA., Logan BK; Center for Forensic Science Research and Education, Fredric Rieders Family Foundation, 206 Welsh Road, Horsham, PA 19044, USA; NMS Labs, 200 Welsh Road, Horsham, PA 19044, USA., Hampson AJ; National Institute on Drug Abuse, National Institutes of Health, 6001 Executive Blvd, North Bethesda, MD 20852, USA., Merchant RC; Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, 1468 Madison Avenue, New York, NY 10029, USA; Morsani College of Medicine, University of South Florida, 560 Channelside Dr, Tampa, FL 33602, USA., Babu KM; Department of Emergency Medicine, University of Massachusetts Chan Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.
Source: Drug and alcohol dependence [Drug Alcohol Depend] 2026 Aug 01; Vol. 285, pp. 113228. Date of Electronic Publication: 2026 Jun 03.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Ireland NLM ID: 7513587 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0046 (Electronic) Linking ISSN: 03768716 NLM ISO Abbreviation: Drug Alcohol Depend Subsets: MEDLINE
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  Data: Pharmacokinetics of xylazine and fentanyl in patients presenting to the emergency department after non-fatal opioid overdose.
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  Data: <searchLink fieldCode="AU" term="%22Krotulski+AJ%22">Krotulski AJ</searchLink>; Center for Forensic Science Research and Education, Fredric Rieders Family Foundation, 206 Welsh Road, Horsham, PA 19044, USA; College of Life Sciences, Thomas Jefferson University, 1020 Locust St, Philadelphia, PA 19107, USA. Electronic address: alex.krotulski@cfsre.org.<br /><searchLink fieldCode="AU" term="%22Baumann+MH%22">Baumann MH</searchLink>; Designer Drug Research Unit, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 333 Cassell Drive, Suite 4400, Baltimore, MD 21224, USA.<br /><searchLink fieldCode="AU" term="%22Chapman+BP%22">Chapman BP</searchLink>; Department of Emergency Medicine, University of Massachusetts Chan Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.<br /><searchLink fieldCode="AU" term="%22Martinez+PME%22">Martinez PME</searchLink>; Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, 1468 Madison Avenue, New York, NY 10029, USA.<br /><searchLink fieldCode="AU" term="%22Broach+JP%22">Broach JP</searchLink>; Department of Emergency Medicine, University of Massachusetts Chan Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+J%22">Nguyen J</searchLink>; Designer Drug Research Unit, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 333 Cassell Drive, Suite 4400, Baltimore, MD 21224, USA.<br /><searchLink fieldCode="AU" term="%22Olabisi+D%22">Olabisi D</searchLink>; Department of Emergency Medicine, University of Massachusetts Chan Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.<br /><searchLink fieldCode="AU" term="%22Polackal+J%22">Polackal J</searchLink>; Department of Emergency Medicine, University of Massachusetts Chan Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.<br /><searchLink fieldCode="AU" term="%22Walton+SE%22">Walton SE</searchLink>; Center for Forensic Science Research and Education, Fredric Rieders Family Foundation, 206 Welsh Road, Horsham, PA 19044, USA.<br /><searchLink fieldCode="AU" term="%22Stang+BN%22">Stang BN</searchLink>; Center for Forensic Science Research and Education, Fredric Rieders Family Foundation, 206 Welsh Road, Horsham, PA 19044, USA.<br /><searchLink fieldCode="AU" term="%22Reyes+AG%22">Reyes AG</searchLink>; Center for Forensic Science Research and Education, Fredric Rieders Family Foundation, 206 Welsh Road, Horsham, PA 19044, USA.<br /><searchLink fieldCode="AU" term="%22Logan+BK%22">Logan BK</searchLink>; Center for Forensic Science Research and Education, Fredric Rieders Family Foundation, 206 Welsh Road, Horsham, PA 19044, USA; NMS Labs, 200 Welsh Road, Horsham, PA 19044, USA.<br /><searchLink fieldCode="AU" term="%22Hampson+AJ%22">Hampson AJ</searchLink>; National Institute on Drug Abuse, National Institutes of Health, 6001 Executive Blvd, North Bethesda, MD 20852, USA.<br /><searchLink fieldCode="AU" term="%22Merchant+RC%22">Merchant RC</searchLink>; Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, 1468 Madison Avenue, New York, NY 10029, USA; Morsani College of Medicine, University of South Florida, 560 Channelside Dr, Tampa, FL 33602, USA.<br /><searchLink fieldCode="AU" term="%22Babu+KM%22">Babu KM</searchLink>; Department of Emergency Medicine, University of Massachusetts Chan Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.
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  Data: <searchLink fieldCode="JN" term="%227513587%22">Drug and alcohol dependence</searchLink> [Drug Alcohol Depend] 2026 Aug 01; Vol. 285, pp. 113228. <i>Date of Electronic Publication: </i>2026 Jun 03.
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        Value: 10.1016/j.drugalcdep.2026.113228
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        Text: English
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      – TitleFull: Pharmacokinetics of xylazine and fentanyl in patients presenting to the emergency department after non-fatal opioid overdose.
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              Text: 2026 Aug 01
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