A chronic whole cigarette smoke extract model reveals redox-mitochondrial adaptation in human lung epithelial and organoid models.

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Title: A chronic whole cigarette smoke extract model reveals redox-mitochondrial adaptation in human lung epithelial and organoid models.
Authors: Lee JE; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea.; Biomedical Convergence Research Institute, Chungnam National University Hospital, Daejeon, Republic of Korea., Lee D; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea., Lee J; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea., Han SJ; Division of Thoracic and Cardiovascular Surgery, College of Medicine, Chungnam National University, Daejeon, Republic of Korea., Kang SH; Division of Climate Change and Health Hazard, Department of Health Hazard Response, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea., Go RE; Division of Climate Change and Health Hazard, Department of Health Hazard Response, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea., Kwon J; Division of Climate Change and Health Hazard, Department of Health Hazard Response, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea., Ahn Y; Division of Climate Change and Health Hazard, Department of Health Hazard Response, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea., Lim MJ; Genomics Department, Keyomics Co. Ltd., Yuseong-gu, Republic of Korea., Lee MJ; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea.; Biomedical Convergence Research Institute, Chungnam National University Hospital, Daejeon, Republic of Korea., Yoo HM; Biometrology Group, Korea Research Institute of Standards and Science (KRISS), Daejeon, Republic of Korea.; Department of Precision Measurement, University of Science and Technology (UST), Daejeon, Republic of Korea., Kang DH; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea., Lee JE; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea., Park D; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea., Chung C; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea. universe7903@gmail.com.
Source: Experimental & molecular medicine [Exp Mol Med] 2026 Jun 08. Date of Electronic Publication: 2026 Jun 08.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9607880 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2092-6413 (Electronic) Linking ISSN: 12263613 NLM ISO Abbreviation: Exp Mol Med Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Lee+JE%22">Lee JE</searchLink>; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea.; Biomedical Convergence Research Institute, Chungnam National University Hospital, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+D%22">Lee D</searchLink>; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Han+SJ%22">Han SJ</searchLink>; Division of Thoracic and Cardiovascular Surgery, College of Medicine, Chungnam National University, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kang+SH%22">Kang SH</searchLink>; Division of Climate Change and Health Hazard, Department of Health Hazard Response, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Go+RE%22">Go RE</searchLink>; Division of Climate Change and Health Hazard, Department of Health Hazard Response, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+J%22">Kwon J</searchLink>; Division of Climate Change and Health Hazard, Department of Health Hazard Response, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ahn+Y%22">Ahn Y</searchLink>; Division of Climate Change and Health Hazard, Department of Health Hazard Response, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lim+MJ%22">Lim MJ</searchLink>; Genomics Department, Keyomics Co. Ltd., Yuseong-gu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+MJ%22">Lee MJ</searchLink>; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea.; Biomedical Convergence Research Institute, Chungnam National University Hospital, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yoo+HM%22">Yoo HM</searchLink>; Biometrology Group, Korea Research Institute of Standards and Science (KRISS), Daejeon, Republic of Korea.; Department of Precision Measurement, University of Science and Technology (UST), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kang+DH%22">Kang DH</searchLink>; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JE%22">Lee JE</searchLink>; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+D%22">Park D</searchLink>; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chung+C%22">Chung C</searchLink>; Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea. universe7903@gmail.com.
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              Text: 2026 Jun 08
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