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A fungal natural product that inhibits plant cellulose biosynthesis by disrupting cellulose synthase complexes.

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Title: A fungal natural product that inhibits plant cellulose biosynthesis by disrupting cellulose synthase complexes.
Authors: Wu Z; State Key Laboratory of Rice Biological Breeding, Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou 310058, China.; Department of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA 90095.; HHMI, University of California at Los Angeles, Los Angeles, CA 90095., Liu L; State Key Laboratory of Rice Biological Breeding, Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou 310058, China., Han W; Department of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, CA 90095., Cai X; Department of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA 90095.; HHMI, University of California at Los Angeles, Los Angeles, CA 90095., Xiao P; State Key Laboratory of Rice Biological Breeding, Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou 310058, China., Sun Z; Department of Chemical and Biomolecular Engineering, University of California at Los Angeles, Los Angeles, CA 90095., Yan C; Department of Chemical and Biomolecular Engineering, University of California at Los Angeles, Los Angeles, CA 90095., Reid S; Department of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, CA 90095., Chen Y; State Key Laboratory of Rice Biological Breeding, Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou 310058, China., Ma Z; State Key Laboratory of Rice Biological Breeding, Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou 310058, China., Tang Y; Department of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, CA 90095.; Department of Chemical and Biomolecular Engineering, University of California at Los Angeles, Los Angeles, CA 90095., Jacobsen SE; Department of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA 90095.; HHMI, University of California at Los Angeles, Los Angeles, CA 90095.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California at Los Angeles, Los Angeles, CA 90095.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Jun 16; Vol. 123 (24), pp. e2602575123. Date of Electronic Publication: 2026 Jun 09.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A fungal natural product that inhibits plant cellulose biosynthesis by disrupting cellulose synthase complexes.
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  Data: <searchLink fieldCode="AU" term="%22Wu+Z%22">Wu Z</searchLink>; State Key Laboratory of Rice Biological Breeding, Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou 310058, China.; Department of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA 90095.; HHMI, University of California at Los Angeles, Los Angeles, CA 90095.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; State Key Laboratory of Rice Biological Breeding, Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou 310058, China.<br /><searchLink fieldCode="AU" term="%22Han+W%22">Han W</searchLink>; Department of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, CA 90095.<br /><searchLink fieldCode="AU" term="%22Cai+X%22">Cai X</searchLink>; Department of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA 90095.; HHMI, University of California at Los Angeles, Los Angeles, CA 90095.<br /><searchLink fieldCode="AU" term="%22Xiao+P%22">Xiao P</searchLink>; State Key Laboratory of Rice Biological Breeding, Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou 310058, China.<br /><searchLink fieldCode="AU" term="%22Sun+Z%22">Sun Z</searchLink>; Department of Chemical and Biomolecular Engineering, University of California at Los Angeles, Los Angeles, CA 90095.<br /><searchLink fieldCode="AU" term="%22Yan+C%22">Yan C</searchLink>; Department of Chemical and Biomolecular Engineering, University of California at Los Angeles, Los Angeles, CA 90095.<br /><searchLink fieldCode="AU" term="%22Reid+S%22">Reid S</searchLink>; Department of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, CA 90095.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; State Key Laboratory of Rice Biological Breeding, Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou 310058, China.<br /><searchLink fieldCode="AU" term="%22Ma+Z%22">Ma Z</searchLink>; State Key Laboratory of Rice Biological Breeding, Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou 310058, China.<br /><searchLink fieldCode="AU" term="%22Tang+Y%22">Tang Y</searchLink>; Department of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, CA 90095.; Department of Chemical and Biomolecular Engineering, University of California at Los Angeles, Los Angeles, CA 90095.<br /><searchLink fieldCode="AU" term="%22Jacobsen+SE%22">Jacobsen SE</searchLink>; Department of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, CA 90095.; HHMI, University of California at Los Angeles, Los Angeles, CA 90095.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California at Los Angeles, Los Angeles, CA 90095.
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              Text: 2026 Jun 16
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