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Top-down medial prefrontal cortex-to-hypothalamic paraventricular nucleus circuit regulates social avoidance and conditioned fear in male mice.

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Title: Top-down medial prefrontal cortex-to-hypothalamic paraventricular nucleus circuit regulates social avoidance and conditioned fear in male mice.
Authors: Wang Y; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China. wangyu10@ustc.edu.cn., Pan XY; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Wu B; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Li DY; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Wang SW; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Qin XY; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Shan QH; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Chen P; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Hu P; Anhui Provincial Key Laboratory for Brain Bank Construction and Resource Utilization, Anhui Medical University, Hefei, Anhui, China., Wang H; Anhui Province Key Laboratory of Biomedical Imaging and Intelligent Processing, Institute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, Anhui, China.; National Engineering Laboratory for Brain-inspired Intelligence Technology and Application, MoE Key Laboratory of Brain-inspired Intelligent Perception and Cognition, School of Information Science and Technology, University of Science and Technology of China, Hefei, Anhui, China., Liu RY; Anhui Geriatrics Institute, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Gong H; HUST-Suzhou Institute for Brainsmatics, JITRI, Suzhou, Jiangsu, China., Zhou JN; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China. jnzhou@ustc.edu.cn.; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China. jnzhou@ustc.edu.cn.
Source: Cell discovery [Cell Discov] 2026 Jun 09; Vol. 12 (1). Date of Electronic Publication: 2026 Jun 09.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101661034 Publication Model: Electronic Cited Medium: Print ISSN: 2056-5968 (Print) Linking ISSN: 20565968 NLM ISO Abbreviation: Cell Discov Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Top-down medial prefrontal cortex-to-hypothalamic paraventricular nucleus circuit regulates social avoidance and conditioned fear in male mice.
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  Data: <searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China. wangyu10@ustc.edu.cn.<br /><searchLink fieldCode="AU" term="%22Pan+XY%22">Pan XY</searchLink>; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.<br /><searchLink fieldCode="AU" term="%22Wu+B%22">Wu B</searchLink>; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.<br /><searchLink fieldCode="AU" term="%22Li+DY%22">Li DY</searchLink>; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.<br /><searchLink fieldCode="AU" term="%22Wang+SW%22">Wang SW</searchLink>; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.<br /><searchLink fieldCode="AU" term="%22Qin+XY%22">Qin XY</searchLink>; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.<br /><searchLink fieldCode="AU" term="%22Shan+QH%22">Shan QH</searchLink>; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.<br /><searchLink fieldCode="AU" term="%22Chen+P%22">Chen P</searchLink>; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.<br /><searchLink fieldCode="AU" term="%22Hu+P%22">Hu P</searchLink>; Anhui Provincial Key Laboratory for Brain Bank Construction and Resource Utilization, Anhui Medical University, Hefei, Anhui, China.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Anhui Province Key Laboratory of Biomedical Imaging and Intelligent Processing, Institute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, Anhui, China.; National Engineering Laboratory for Brain-inspired Intelligence Technology and Application, MoE Key Laboratory of Brain-inspired Intelligent Perception and Cognition, School of Information Science and Technology, University of Science and Technology of China, Hefei, Anhui, China.<br /><searchLink fieldCode="AU" term="%22Liu+RY%22">Liu RY</searchLink>; Anhui Geriatrics Institute, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.<br /><searchLink fieldCode="AU" term="%22Gong+H%22">Gong H</searchLink>; HUST-Suzhou Institute for Brainsmatics, JITRI, Suzhou, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Zhou+JN%22">Zhou JN</searchLink>; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China. jnzhou@ustc.edu.cn.; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China. jnzhou@ustc.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101661034%22">Cell discovery</searchLink> [Cell Discov] 2026 Jun 09; Vol. 12 (1). <i>Date of Electronic Publication: </i>2026 Jun 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101661034 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2056-5968 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220565968%22">20565968 </searchLink><i>NLM ISO Abbreviation: </i>Cell Discov <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2026 Jun 09
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