View in EDS HTML Full Text PDF Full Text

Immune microenvironment and noncoding RNA shape early colorectal carcinogenesis in patients with premalignant lesions.

Saved in:
Bibliographic Details
Title: Immune microenvironment and noncoding RNA shape early colorectal carcinogenesis in patients with premalignant lesions.
Authors: Morgand E; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France., Van den Eynde M; Institut Roi Albert II, Department of Medical Oncology Cliniques Universitaires St-Luc and Institut de Recherche Clinique et Experimentale (Pole MIRO), Université Catholique de Louvain, 1200 Brussels, Belgium., Nguyen H; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France., Batto AF; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France., Mlecnik B; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France., Baldin P; Department of Pathology, Cliniques Universitaires St-Luc and Institut de Recherche Clinique et Experimentale (Pole GAEN) Université Catholique de Louvain, 1200 Brussels, Belgium., Majdi A; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France., Fredriksen T; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France., Lafontaine L; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France., Bindea G; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France., Mezine F; Université Paris Cité, INSERM U970 PARCC, Paris Institute for Transplantation and Organ Regeneration, 75015 Paris, France., Shararah M; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France., Vasaturo A; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France., Hijazi A; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France., Buttard B; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France., Maby P; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France., Ramos RN; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France., Gragera P; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France., Kirilovsky A; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.; Assistance Publique-Hôpitaux de Paris (AP-HP), Immunomonitoring Platform, Laboratory of Immunology, Georges Pompidou European Hospital, 75015 Paris, France., El Sissy C; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.; Assistance Publique-Hôpitaux de Paris (AP-HP), Immunomonitoring Platform, Laboratory of Immunology, Georges Pompidou European Hospital, 75015 Paris, France., Marliot F; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.; Assistance Publique-Hôpitaux de Paris (AP-HP), Immunomonitoring Platform, Laboratory of Immunology, Georges Pompidou European Hospital, 75015 Paris, France., Pagès F; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.; Assistance Publique-Hôpitaux de Paris (AP-HP), Immunomonitoring Platform, Laboratory of Immunology, Georges Pompidou European Hospital, 75015 Paris, France., Vempalli FR; Sidra Medicine, P.O. Box 26999, Doha, Qatar., Hendrickx W; Sidra Medicine, P.O. Box 26999, Doha, Qatar., Masoodi T; Sidra Medicine, P.O. Box 26999, Doha, Qatar., Ceccarelli M; Sylvester Comprehensive Cancer Center and Department of Public Health Sciences, University of Miami, Miami, FL 33136, USA., Bedognetti D; Sidra Medicine, P.O. Box 26999, Doha, Qatar.; Department of Internal Medicine, University of Genoa, 16132 Genoa, Italy., Galon J; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.
Source: Science translational medicine [Sci Transl Med] 2026 Jun 10; Vol. 18 (853), pp. eaed2424. Date of Electronic Publication: 2026 Jun 10.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42268933
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Immune microenvironment and noncoding RNA shape early colorectal carcinogenesis in patients with premalignant lesions.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Morgand+E%22">Morgand E</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.<br /><searchLink fieldCode="AU" term="%22Van+den+Eynde+M%22">Van den Eynde M</searchLink>; Institut Roi Albert II, Department of Medical Oncology Cliniques Universitaires St-Luc and Institut de Recherche Clinique et Experimentale (Pole MIRO), Université Catholique de Louvain, 1200 Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Nguyen+H%22">Nguyen H</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.<br /><searchLink fieldCode="AU" term="%22Batto+AF%22">Batto AF</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.<br /><searchLink fieldCode="AU" term="%22Mlecnik+B%22">Mlecnik B</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.<br /><searchLink fieldCode="AU" term="%22Baldin+P%22">Baldin P</searchLink>; Department of Pathology, Cliniques Universitaires St-Luc and Institut de Recherche Clinique et Experimentale (Pole GAEN) Université Catholique de Louvain, 1200 Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Majdi+A%22">Majdi A</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.<br /><searchLink fieldCode="AU" term="%22Fredriksen+T%22">Fredriksen T</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.<br /><searchLink fieldCode="AU" term="%22Lafontaine+L%22">Lafontaine L</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.<br /><searchLink fieldCode="AU" term="%22Bindea+G%22">Bindea G</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.<br /><searchLink fieldCode="AU" term="%22Mezine+F%22">Mezine F</searchLink>; Université Paris Cité, INSERM U970 PARCC, Paris Institute for Transplantation and Organ Regeneration, 75015 Paris, France.<br /><searchLink fieldCode="AU" term="%22Shararah+M%22">Shararah M</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.<br /><searchLink fieldCode="AU" term="%22Vasaturo+A%22">Vasaturo A</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.<br /><searchLink fieldCode="AU" term="%22Hijazi+A%22">Hijazi A</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.<br /><searchLink fieldCode="AU" term="%22Buttard+B%22">Buttard B</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.<br /><searchLink fieldCode="AU" term="%22Maby+P%22">Maby P</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.<br /><searchLink fieldCode="AU" term="%22Ramos+RN%22">Ramos RN</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.<br /><searchLink fieldCode="AU" term="%22Gragera+P%22">Gragera P</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.<br /><searchLink fieldCode="AU" term="%22Kirilovsky+A%22">Kirilovsky A</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.; Assistance Publique-Hôpitaux de Paris (AP-HP), Immunomonitoring Platform, Laboratory of Immunology, Georges Pompidou European Hospital, 75015 Paris, France.<br /><searchLink fieldCode="AU" term="%22El+Sissy+C%22">El Sissy C</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.; Assistance Publique-Hôpitaux de Paris (AP-HP), Immunomonitoring Platform, Laboratory of Immunology, Georges Pompidou European Hospital, 75015 Paris, France.<br /><searchLink fieldCode="AU" term="%22Marliot+F%22">Marliot F</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.; Assistance Publique-Hôpitaux de Paris (AP-HP), Immunomonitoring Platform, Laboratory of Immunology, Georges Pompidou European Hospital, 75015 Paris, France.<br /><searchLink fieldCode="AU" term="%22Pagès+F%22">Pagès F</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.; Assistance Publique-Hôpitaux de Paris (AP-HP), Immunomonitoring Platform, Laboratory of Immunology, Georges Pompidou European Hospital, 75015 Paris, France.<br /><searchLink fieldCode="AU" term="%22Vempalli+FR%22">Vempalli FR</searchLink>; Sidra Medicine, P.O. Box 26999, Doha, Qatar.<br /><searchLink fieldCode="AU" term="%22Hendrickx+W%22">Hendrickx W</searchLink>; Sidra Medicine, P.O. Box 26999, Doha, Qatar.<br /><searchLink fieldCode="AU" term="%22Masoodi+T%22">Masoodi T</searchLink>; Sidra Medicine, P.O. Box 26999, Doha, Qatar.<br /><searchLink fieldCode="AU" term="%22Ceccarelli+M%22">Ceccarelli M</searchLink>; Sylvester Comprehensive Cancer Center and Department of Public Health Sciences, University of Miami, Miami, FL 33136, USA.<br /><searchLink fieldCode="AU" term="%22Bedognetti+D%22">Bedognetti D</searchLink>; Sidra Medicine, P.O. Box 26999, Doha, Qatar.; Department of Internal Medicine, University of Genoa, 16132 Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Galon+J%22">Galon J</searchLink>; INSERM, Laboratory of Integrative Cancer Immunology, F-75006 Paris, France.; Equipe Labellisée Ligue Contre le Cancer, F-75006 Paris, France.; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, F-75006 Paris, France.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2026 Jun 10; Vol. 18 (853), pp. eaed2424. <i>Date of Electronic Publication: </i>2026 Jun 10.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101505086 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1946-6242 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219466234%22">19466234 </searchLink><i>NLM ISO Abbreviation: </i>Sci Transl Med <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42268933
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1126/scitranslmed.aed2424
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: eaed2424
    Titles:
      – TitleFull: Immune microenvironment and noncoding RNA shape early colorectal carcinogenesis in patients with premalignant lesions.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Morgand E
      – PersonEntity:
          Name:
            NameFull: Van den Eynde M
      – PersonEntity:
          Name:
            NameFull: Nguyen H
      – PersonEntity:
          Name:
            NameFull: Batto AF
      – PersonEntity:
          Name:
            NameFull: Mlecnik B
      – PersonEntity:
          Name:
            NameFull: Baldin P
      – PersonEntity:
          Name:
            NameFull: Majdi A
      – PersonEntity:
          Name:
            NameFull: Fredriksen T
      – PersonEntity:
          Name:
            NameFull: Lafontaine L
      – PersonEntity:
          Name:
            NameFull: Bindea G
      – PersonEntity:
          Name:
            NameFull: Mezine F
      – PersonEntity:
          Name:
            NameFull: Shararah M
      – PersonEntity:
          Name:
            NameFull: Vasaturo A
      – PersonEntity:
          Name:
            NameFull: Hijazi A
      – PersonEntity:
          Name:
            NameFull: Buttard B
      – PersonEntity:
          Name:
            NameFull: Maby P
      – PersonEntity:
          Name:
            NameFull: Ramos RN
      – PersonEntity:
          Name:
            NameFull: Gragera P
      – PersonEntity:
          Name:
            NameFull: Kirilovsky A
      – PersonEntity:
          Name:
            NameFull: El Sissy C
      – PersonEntity:
          Name:
            NameFull: Marliot F
      – PersonEntity:
          Name:
            NameFull: Pagès F
      – PersonEntity:
          Name:
            NameFull: Vempalli FR
      – PersonEntity:
          Name:
            NameFull: Hendrickx W
      – PersonEntity:
          Name:
            NameFull: Masoodi T
      – PersonEntity:
          Name:
            NameFull: Ceccarelli M
      – PersonEntity:
          Name:
            NameFull: Bedognetti D
      – PersonEntity:
          Name:
            NameFull: Galon J
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 10
              M: 06
              Text: 2026 Jun 10
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1946-6242
          Numbering:
            – Type: volume
              Value: 18
            – Type: issue
              Value: 853
          Titles:
            – TitleFull: Science translational medicine
              Type: main
ResultId 1