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Single-cell transcriptomics reveals differences between chorionic and basal plate cytotrophoblasts and 2D-cultured trophoblast stem cells.

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Title: Single-cell transcriptomics reveals differences between chorionic and basal plate cytotrophoblasts and 2D-cultured trophoblast stem cells.
Authors: Morey R; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA., Soncin F; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA., Kallol S; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA., Sah N; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA., Manalo Z; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA., Bui TA; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA., Slamecka J; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA., Cheung VC; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA., Pizzo D; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA., Requena DF; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA., Chang CW; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA., Farah O; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA., Kittle R; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA., Lam K; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA., Meads M; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA., Horii M; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA., Fisch KM; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of California San Diego, La Jolla, CA, USA., Parast MM; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA. mparast@health.ucsd.edu.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA. mparast@health.ucsd.edu.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA. mparast@health.ucsd.edu.
Source: Communications biology [Commun Biol] 2026 Jun 10. Date of Electronic Publication: 2026 Jun 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE
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  Data: Single-cell transcriptomics reveals differences between chorionic and basal plate cytotrophoblasts and 2D-cultured trophoblast stem cells.
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  Data: <searchLink fieldCode="AU" term="%22Morey+R%22">Morey R</searchLink>; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Soncin+F%22">Soncin F</searchLink>; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kallol+S%22">Kallol S</searchLink>; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sah+N%22">Sah N</searchLink>; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Manalo+Z%22">Manalo Z</searchLink>; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bui+TA%22">Bui TA</searchLink>; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Slamecka+J%22">Slamecka J</searchLink>; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cheung+VC%22">Cheung VC</searchLink>; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Pizzo+D%22">Pizzo D</searchLink>; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Requena+DF%22">Requena DF</searchLink>; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chang+CW%22">Chang CW</searchLink>; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Farah+O%22">Farah O</searchLink>; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kittle+R%22">Kittle R</searchLink>; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lam+K%22">Lam K</searchLink>; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Meads+M%22">Meads M</searchLink>; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Horii+M%22">Horii M</searchLink>; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Fisch+KM%22">Fisch KM</searchLink>; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Parast+MM%22">Parast MM</searchLink>; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA. mparast@health.ucsd.edu.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA. mparast@health.ucsd.edu.; Center for Perinatal Discovery, University of California San Diego, La Jolla, CA, USA. mparast@health.ucsd.edu.
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