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Acute non-alcoholic caffeinated beverage consumption as a trigger for cryptogenic ischemic stroke in the young: findings from the SECRETO study.

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Title: Acute non-alcoholic caffeinated beverage consumption as a trigger for cryptogenic ischemic stroke in the young: findings from the SECRETO study.
Authors: Ferdinand P; Neurosciences, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, UK. phillip.ferdinand@uhnm.nhs.uk.; School of Medicine, Keele University, Staffordshire, UK. phillip.ferdinand@uhnm.nhs.uk., Bajpai R; School of Medicine, Keele University, Staffordshire, UK., von Sarnowski B; Department of Neurology, University Medicine Greifswald, Greifswald, Germany., Ylikotila P; Department of Neurology, Turku University Hospital and University of Turku, Turku, Finland., Zedde M; Neurology Unit, Stroke Unit, Azienda Unità Sanitaria Locale-IRCCS Reggio Emilia, Reggio Emilia, Italy., Sarkanen T; Department of Neurology, Tampere University Hospital, Tampere, Finland.; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Ryliskiene K; Faculty of Medicine, Center of Neurology, Vilnius University, Vilnius, Lithuania., Martinez-Majander N; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Tulkki L; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Licenik R; North West Anglia NHS Foundation Trust Acute Stroke Centre, Peterborough, UK., Kõrv J; Department of Neurology and Neurosurgery, University of Tartu, Tartu, Estonia., Kõrv L; Department of Neurology and Neurosurgery, University of Tartu, Tartu, Estonia., Pezzini A; Department of Medicine and Surgery, University of Parma, Parma, Italy.; Stroke Care Program, Department of Emergency, Parma University Hospital, Parma, Italy., Fonseca AC; Hospital Santa Maria, CHLN, Faculty of Medicine, University of Lisbon, Lisbon, Portugal., Martinez-Sanchez P; Department of Neurology, Torrecardenas University Hospital, University of Almería, Almería, Spain., Amaya-Pascasio L; Department of Neurology, Torrecardenas University Hospital, University of Almería, Almería, Spain., Yesilot N; Istanbul Faculty of Medicine, Department of Neurology, Istanbul University, Istanbul, Turkey., Waje-Andreassen U; Department of Neurology, Haukeland University Hospital, Bergen, Norway., Fromm A; Department of Neurology, Haukeland University Hospital, Bergen, Norway., Huhtakangas J; Department of Neurology, Oulu University Hospital and University of Oulu, Oulu, Finland., Junttola U; Department of Neurology, Oulu University Hospital and University of Oulu, Oulu, Finland., Jäkälä P; Neurocenter Neurology, Kuopio University Hospital, Kuopio, Finland., Kantanen AM; Neurocenter Neurology, Kuopio University Hospital, Kuopio, Finland.; University of Eastern Finland, Joensuu, Finland., Redfors P; Department of Neurology, Sahlgrenska University Hospital, Gothenburg, Sweden.; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden., Sinisalo J; Department of Cardiology, Heart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Gerdts E; Center for Research On Cardiac Disease in Women, Department of Clinical Science, University of Bergen, Bergen, Norway., Tatlisumak T; Department of Neurology, Sahlgrenska University Hospital, Gothenburg, Sweden., Roffe C; Neurosciences, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, UK.; School of Medicine, Keele University, Staffordshire, UK., Putaala J; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Source: Journal of neurology [J Neurol] 2026 Jun 11; Vol. 273 (7). Date of Electronic Publication: 2026 Jun 11.
Publication Type: Journal Article; Multicenter Study; Observational Study
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0423161 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1459 (Electronic) Linking ISSN: 03405354 NLM ISO Abbreviation: J Neurol Subsets: MEDLINE
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  Data: Acute non-alcoholic caffeinated beverage consumption as a trigger for cryptogenic ischemic stroke in the young: findings from the SECRETO study.
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  Data: <searchLink fieldCode="AU" term="%22Ferdinand+P%22">Ferdinand P</searchLink>; Neurosciences, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, UK. phillip.ferdinand@uhnm.nhs.uk.; School of Medicine, Keele University, Staffordshire, UK. phillip.ferdinand@uhnm.nhs.uk.<br /><searchLink fieldCode="AU" term="%22Bajpai+R%22">Bajpai R</searchLink>; School of Medicine, Keele University, Staffordshire, UK.<br /><searchLink fieldCode="AU" term="%22von+Sarnowski+B%22">von Sarnowski B</searchLink>; Department of Neurology, University Medicine Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Ylikotila+P%22">Ylikotila P</searchLink>; Department of Neurology, Turku University Hospital and University of Turku, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Zedde+M%22">Zedde M</searchLink>; Neurology Unit, Stroke Unit, Azienda Unità Sanitaria Locale-IRCCS Reggio Emilia, Reggio Emilia, Italy.<br /><searchLink fieldCode="AU" term="%22Sarkanen+T%22">Sarkanen T</searchLink>; Department of Neurology, Tampere University Hospital, Tampere, Finland.; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.<br /><searchLink fieldCode="AU" term="%22Ryliskiene+K%22">Ryliskiene K</searchLink>; Faculty of Medicine, Center of Neurology, Vilnius University, Vilnius, Lithuania.<br /><searchLink fieldCode="AU" term="%22Martinez-Majander+N%22">Martinez-Majander N</searchLink>; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Tulkki+L%22">Tulkki L</searchLink>; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Licenik+R%22">Licenik R</searchLink>; North West Anglia NHS Foundation Trust Acute Stroke Centre, Peterborough, UK.<br /><searchLink fieldCode="AU" term="%22Kõrv+J%22">Kõrv J</searchLink>; Department of Neurology and Neurosurgery, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Kõrv+L%22">Kõrv L</searchLink>; Department of Neurology and Neurosurgery, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Pezzini+A%22">Pezzini A</searchLink>; Department of Medicine and Surgery, University of Parma, Parma, Italy.; Stroke Care Program, Department of Emergency, Parma University Hospital, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Fonseca+AC%22">Fonseca AC</searchLink>; Hospital Santa Maria, CHLN, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Martinez-Sanchez+P%22">Martinez-Sanchez P</searchLink>; Department of Neurology, Torrecardenas University Hospital, University of Almería, Almería, Spain.<br /><searchLink fieldCode="AU" term="%22Amaya-Pascasio+L%22">Amaya-Pascasio L</searchLink>; Department of Neurology, Torrecardenas University Hospital, University of Almería, Almería, Spain.<br /><searchLink fieldCode="AU" term="%22Yesilot+N%22">Yesilot N</searchLink>; Istanbul Faculty of Medicine, Department of Neurology, Istanbul University, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Waje-Andreassen+U%22">Waje-Andreassen U</searchLink>; Department of Neurology, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Fromm+A%22">Fromm A</searchLink>; Department of Neurology, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Huhtakangas+J%22">Huhtakangas J</searchLink>; Department of Neurology, Oulu University Hospital and University of Oulu, Oulu, Finland.<br /><searchLink fieldCode="AU" term="%22Junttola+U%22">Junttola U</searchLink>; Department of Neurology, Oulu University Hospital and University of Oulu, Oulu, Finland.<br /><searchLink fieldCode="AU" term="%22Jäkälä+P%22">Jäkälä P</searchLink>; Neurocenter Neurology, Kuopio University Hospital, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Kantanen+AM%22">Kantanen AM</searchLink>; Neurocenter Neurology, Kuopio University Hospital, Kuopio, Finland.; University of Eastern Finland, Joensuu, Finland.<br /><searchLink fieldCode="AU" term="%22Redfors+P%22">Redfors P</searchLink>; Department of Neurology, Sahlgrenska University Hospital, Gothenburg, Sweden.; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Sinisalo+J%22">Sinisalo J</searchLink>; Department of Cardiology, Heart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Gerdts+E%22">Gerdts E</searchLink>; Center for Research On Cardiac Disease in Women, Department of Clinical Science, University of Bergen, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Tatlisumak+T%22">Tatlisumak T</searchLink>; Department of Neurology, Sahlgrenska University Hospital, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Roffe+C%22">Roffe C</searchLink>; Neurosciences, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, UK.; School of Medicine, Keele University, Staffordshire, UK.<br /><searchLink fieldCode="AU" term="%22Putaala+J%22">Putaala J</searchLink>; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
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