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Integrating chromatin accessibility and GWAS identifies RUNX3 and TRAF1 as susceptibility genes for rheumatoid arthritis.

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Title: Integrating chromatin accessibility and GWAS identifies RUNX3 and TRAF1 as susceptibility genes for rheumatoid arthritis.
Authors: Wang NN; Department of Orthopedics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061 Shaanxi, China.; Key Laboratory of Biomedical Information Engineering of Ministry of Education, Key Laboratory of Biology Multiomics and Diseases in Shaanxi Province Higher Education Institutions, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China., Zhu DL; Key Laboratory of Biomedical Information Engineering of Ministry of Education, Key Laboratory of Biology Multiomics and Diseases in Shaanxi Province Higher Education Institutions, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China., Jiang F; Key Laboratory of Biomedical Information Engineering of Ministry of Education, Key Laboratory of Biology Multiomics and Diseases in Shaanxi Province Higher Education Institutions, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China., Zhang Y; Key Laboratory of Biomedical Information Engineering of Ministry of Education, Key Laboratory of Biology Multiomics and Diseases in Shaanxi Province Higher Education Institutions, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China., Li M; Department of Orthopedics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061 Shaanxi, China., Zhang DJ; Key Laboratory of Biomedical Information Engineering of Ministry of Education, Key Laboratory of Biology Multiomics and Diseases in Shaanxi Province Higher Education Institutions, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China., Dong SS; Key Laboratory of Biomedical Information Engineering of Ministry of Education, Key Laboratory of Biology Multiomics and Diseases in Shaanxi Province Higher Education Institutions, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China., Zhi LQ; Department of Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, P. R. China., Yang TL; Key Laboratory of Biomedical Information Engineering of Ministry of Education, Key Laboratory of Biology Multiomics and Diseases in Shaanxi Province Higher Education Institutions, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China., Hu SY; Department of Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, P. R. China., Guo Y; Key Laboratory of Biomedical Information Engineering of Ministry of Education, Key Laboratory of Biology Multiomics and Diseases in Shaanxi Province Higher Education Institutions, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China.
Source: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research [J Bone Miner Res] 2026 Jun 11. Date of Electronic Publication: 2026 Jun 11.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8610640 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-4681 (Electronic) Linking ISSN: 08840431 NLM ISO Abbreviation: J Bone Miner Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Integrating chromatin accessibility and GWAS identifies RUNX3 and TRAF1 as susceptibility genes for rheumatoid arthritis.
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  Data: <searchLink fieldCode="AU" term="%22Wang+NN%22">Wang NN</searchLink>; Department of Orthopedics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061 Shaanxi, China.; Key Laboratory of Biomedical Information Engineering of Ministry of Education, Key Laboratory of Biology Multiomics and Diseases in Shaanxi Province Higher Education Institutions, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhu+DL%22">Zhu DL</searchLink>; Key Laboratory of Biomedical Information Engineering of Ministry of Education, Key Laboratory of Biology Multiomics and Diseases in Shaanxi Province Higher Education Institutions, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China.<br /><searchLink fieldCode="AU" term="%22Jiang+F%22">Jiang F</searchLink>; Key Laboratory of Biomedical Information Engineering of Ministry of Education, Key Laboratory of Biology Multiomics and Diseases in Shaanxi Province Higher Education Institutions, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Key Laboratory of Biomedical Information Engineering of Ministry of Education, Key Laboratory of Biology Multiomics and Diseases in Shaanxi Province Higher Education Institutions, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China.<br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink>; Department of Orthopedics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061 Shaanxi, China.<br /><searchLink fieldCode="AU" term="%22Zhang+DJ%22">Zhang DJ</searchLink>; Key Laboratory of Biomedical Information Engineering of Ministry of Education, Key Laboratory of Biology Multiomics and Diseases in Shaanxi Province Higher Education Institutions, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China.<br /><searchLink fieldCode="AU" term="%22Dong+SS%22">Dong SS</searchLink>; Key Laboratory of Biomedical Information Engineering of Ministry of Education, Key Laboratory of Biology Multiomics and Diseases in Shaanxi Province Higher Education Institutions, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhi+LQ%22">Zhi LQ</searchLink>; Department of Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, P. R. China.<br /><searchLink fieldCode="AU" term="%22Yang+TL%22">Yang TL</searchLink>; Key Laboratory of Biomedical Information Engineering of Ministry of Education, Key Laboratory of Biology Multiomics and Diseases in Shaanxi Province Higher Education Institutions, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China.<br /><searchLink fieldCode="AU" term="%22Hu+SY%22">Hu SY</searchLink>; Department of Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, P. R. China.<br /><searchLink fieldCode="AU" term="%22Guo+Y%22">Guo Y</searchLink>; Key Laboratory of Biomedical Information Engineering of Ministry of Education, Key Laboratory of Biology Multiomics and Diseases in Shaanxi Province Higher Education Institutions, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China.
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  Data: <searchLink fieldCode="JN" term="%228610640%22">Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research</searchLink> [J Bone Miner Res] 2026 Jun 11. <i>Date of Electronic Publication: </i>2026 Jun 11.
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        Value: 10.1093/jbmr/zjag098
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      – TitleFull: Integrating chromatin accessibility and GWAS identifies RUNX3 and TRAF1 as susceptibility genes for rheumatoid arthritis.
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              Text: 2026 Jun 11
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