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Strain-specific propagation of variant Creutzfeldt-Jakob disease prions in humanized neural cells.

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Bibliographic Details
Title: Strain-specific propagation of variant Creutzfeldt-Jakob disease prions in humanized neural cells.
Authors: Rayner MLD; Medical Research Council Prion Unit at UCL, UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom.; Department of Pharmacology, UCL School of Pharmacy, University College London, London WC1N 1AX, United Kingdom., Arora P; Medical Research Council Prion Unit at UCL, UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom., Linehan JM; Medical Research Council Prion Unit at UCL, UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom., Ros H; Medical Research Council Prion Unit at UCL, UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom., Nihat A; Medical Research Council Prion Unit at UCL, UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom.; National Health Service National Prion Clinic, National Hospital for Neurology and Neurosurgery, University College London Hospitals National Health Service Foundation Trust, London WC1N 3BG, United Kingdom., Argentina F; Medical Research Council Prion Unit at UCL, UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom., Preston C; Medical Research Council Prion Unit at UCL, UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom., Schmidt C; Medical Research Council Prion Unit at UCL, UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom., Ribes JM; Medical Research Council Prion Unit at UCL, UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom., Klöhn PC; Medical Research Council Prion Unit at UCL, UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom., Mead S; Medical Research Council Prion Unit at UCL, UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom.; National Health Service National Prion Clinic, National Hospital for Neurology and Neurosurgery, University College London Hospitals National Health Service Foundation Trust, London WC1N 3BG, United Kingdom., Brandner S; Division of Neuropathology, The National Hospital for Neurology and Neurosurgery, University College National Health Service Foundation Trust, London WC1N 3BG, United Kingdom.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London WC1N 3BG, United Kingdom., Collinge J; Medical Research Council Prion Unit at UCL, UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom.; National Health Service National Prion Clinic, National Hospital for Neurology and Neurosurgery, University College London Hospitals National Health Service Foundation Trust, London WC1N 3BG, United Kingdom., Jat PS; Medical Research Council Prion Unit at UCL, UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Jun 16; Vol. 123 (24), pp. e2609054123. Date of Electronic Publication: 2026 Jun 11.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1091-6490
DOI:10.1073/pnas.2609054123