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Circulating cell type senescence signatures track distinct dimensions of health status and trajectories in human longitudinal cohorts.

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Title: Circulating cell type senescence signatures track distinct dimensions of health status and trajectories in human longitudinal cohorts.
Authors: Olinger B; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA; Department of Biology, Johns Hopkins University, Baltimore, MD, USA., Anerillas C; Tissue and Organ Homeostasis Program, Centro de Biología Molecular Severo Ochoa (CBM), Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain., Herman AB; Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD, USA., Tsitsipatis D; Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD, USA., Banarjee R; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA., Tanaka T; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA., Candia J; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA., Maragkakis M; Laboratory of Genetics and Genomics, National Institute on Aging, NIH, Baltimore, MD, USA., Bandinelli S; Geriatric Unit, Azienda Sanitaria Toscana Centro, Firenze, Italy., Walker KA; Laboratory of Behavioral Neuroscience, National Institute on Aging, NIH, Baltimore, MD, USA., Simonsick EM; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA., Qi YA; Center for Alzheimer's Disease and Related Dementias, National Institute on Aging, NIH, Bethesda, MD, USA., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA., Gorospe M; Laboratory of Genetics and Genomics, National Institute on Aging, NIH, Baltimore, MD, USA., Basisty N; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA. Electronic address: nathan.basisty@nih.gov.
Source: Cell reports [Cell Rep] 2026 Jun 23; Vol. 45 (6), pp. 117389. Date of Electronic Publication: 2026 Jun 11.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Circulating cell type senescence signatures track distinct dimensions of health status and trajectories in human longitudinal cohorts.
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  Data: <searchLink fieldCode="AU" term="%22Olinger+B%22">Olinger B</searchLink>; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA; Department of Biology, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Anerillas+C%22">Anerillas C</searchLink>; Tissue and Organ Homeostasis Program, Centro de Biología Molecular Severo Ochoa (CBM), Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Herman+AB%22">Herman AB</searchLink>; Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Tsitsipatis+D%22">Tsitsipatis D</searchLink>; Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Banarjee+R%22">Banarjee R</searchLink>; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Tanaka+T%22">Tanaka T</searchLink>; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Candia+J%22">Candia J</searchLink>; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Maragkakis+M%22">Maragkakis M</searchLink>; Laboratory of Genetics and Genomics, National Institute on Aging, NIH, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Bandinelli+S%22">Bandinelli S</searchLink>; Geriatric Unit, Azienda Sanitaria Toscana Centro, Firenze, Italy.<br /><searchLink fieldCode="AU" term="%22Walker+KA%22">Walker KA</searchLink>; Laboratory of Behavioral Neuroscience, National Institute on Aging, NIH, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Simonsick+EM%22">Simonsick EM</searchLink>; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Qi+YA%22">Qi YA</searchLink>; Center for Alzheimer's Disease and Related Dementias, National Institute on Aging, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ferrucci+L%22">Ferrucci L</searchLink>; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Gorospe+M%22">Gorospe M</searchLink>; Laboratory of Genetics and Genomics, National Institute on Aging, NIH, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Basisty+N%22">Basisty N</searchLink>; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA. Electronic address: nathan.basisty@nih.gov.
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  Data: <searchLink fieldCode="JN" term="%22101573691%22">Cell reports</searchLink> [Cell Rep] 2026 Jun 23; Vol. 45 (6), pp. 117389. <i>Date of Electronic Publication: </i>2026 Jun 11.
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              Text: 2026 Jun 23
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