Low concentration atropine eye drops and progression of myopia in children: multicentre placebo controlled, double masked, randomised trial in the UK (CHAMP-UK).

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Title: Low concentration atropine eye drops and progression of myopia in children: multicentre placebo controlled, double masked, randomised trial in the UK (CHAMP-UK).
Authors: Azuara-Blanco A; Centre for Public Health, Queen's University Belfast, Belfast, UK a.azuara-blanco@qub.ac.uk., Logan NS; School of Optometry, Aston University, Birmingham, UK., McConnell E; Northern Ireland Clinical Research Facility, Belfast, Ireland, UK., Kearney S; Department of Vision Sciences, Glasgow Caledonian University, Glasgow, UK., Kirk G; Vision and Hearing Sciences Research Centre, Anglia Ruskin University, Cambridge, UK., Jones S; School of Optometry, Aston University, Birmingham, UK., McDowell C; Northern Ireland Clinical Trials Unit, Belfast, Ireland, UK., Murphy L; Northern Ireland Clinical Trials Unit, Belfast, Ireland, UK., O'Hanlon G; Northern Ireland Clinical Trials Unit, Belfast, Ireland, UK., McFarland M; Department of Pharmacy, Belfast Health and Social Care Trust, Belfast, Ireland, UK., Painter S; Birmingham Women and Children's NHS Foundation Trust, Birmingham, UK., Muthusamy B; Addenbrooke's Hospital, Cambridge, UK., Nabili S; NHS Lanarkshire, UK., Preston J; Institute of Translational Medicine, University of Liverpool, Liverpool, UK., Flitcroft I; Centre for Eye Research Ireland, Technological University Dublin, Dublin, Ireland., Loughman J; Optometry School, Technological University Dublin, Dublin, Ireland., Mackey D; Lions Eye Institute, University of Western Australia, Perth, Australia., Lee S; Lions Eye Institute, University of Western Australia, Perth, Australia., Dahlmann-Noor A; NIHR Moorfields Biomedical Research Centre, London, UK., Congdon N; Centre for Public Health, Queen's University Belfast, Belfast, UK.; Orbis International, New York, USA.; Zhongshan Ophthalmic Centre, Sun Yat-sen University, Guangzhou, China., Hogg RE; Centre for Public Health, Queen's University Belfast, Belfast, UK., Hammond CJ; King's College London, London, UK., Saunders K; School of Biomedical Sciences, Ulster University, Coleraine, UK., Allen PM; Northern Ireland Clinical Research Facility, Belfast, Ireland, UK., Strang N; Department of Vision Sciences, Glasgow Caledonian University, Glasgow, UK., Clarke M; Centre for Public Health, Queen's University Belfast, Belfast, UK.; Northern Ireland Clinical Trials Unit, Belfast, Ireland, UK.
Source: BMJ (Clinical research ed.) [BMJ] 2026 Jun 11; Vol. 393, pp. e086698. Date of Electronic Publication: 2026 Jun 11.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: British Medical Association Country of Publication: England NLM ID: 8900488 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-1833 (Electronic) Linking ISSN: 09598138 NLM ISO Abbreviation: BMJ Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Low concentration atropine eye drops and progression of myopia in children: multicentre placebo controlled, double masked, randomised trial in the UK (CHAMP-UK).
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  Data: <searchLink fieldCode="AU" term="%22Azuara-Blanco+A%22">Azuara-Blanco A</searchLink>; Centre for Public Health, Queen's University Belfast, Belfast, UK a.azuara-blanco@qub.ac.uk.<br /><searchLink fieldCode="AU" term="%22Logan+NS%22">Logan NS</searchLink>; School of Optometry, Aston University, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22McConnell+E%22">McConnell E</searchLink>; Northern Ireland Clinical Research Facility, Belfast, Ireland, UK.<br /><searchLink fieldCode="AU" term="%22Kearney+S%22">Kearney S</searchLink>; Department of Vision Sciences, Glasgow Caledonian University, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Kirk+G%22">Kirk G</searchLink>; Vision and Hearing Sciences Research Centre, Anglia Ruskin University, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Jones+S%22">Jones S</searchLink>; School of Optometry, Aston University, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22McDowell+C%22">McDowell C</searchLink>; Northern Ireland Clinical Trials Unit, Belfast, Ireland, UK.<br /><searchLink fieldCode="AU" term="%22Murphy+L%22">Murphy L</searchLink>; Northern Ireland Clinical Trials Unit, Belfast, Ireland, UK.<br /><searchLink fieldCode="AU" term="%22O'Hanlon+G%22">O'Hanlon G</searchLink>; Northern Ireland Clinical Trials Unit, Belfast, Ireland, UK.<br /><searchLink fieldCode="AU" term="%22McFarland+M%22">McFarland M</searchLink>; Department of Pharmacy, Belfast Health and Social Care Trust, Belfast, Ireland, UK.<br /><searchLink fieldCode="AU" term="%22Painter+S%22">Painter S</searchLink>; Birmingham Women and Children's NHS Foundation Trust, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Muthusamy+B%22">Muthusamy B</searchLink>; Addenbrooke's Hospital, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Nabili+S%22">Nabili S</searchLink>; NHS Lanarkshire, UK.<br /><searchLink fieldCode="AU" term="%22Preston+J%22">Preston J</searchLink>; Institute of Translational Medicine, University of Liverpool, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Flitcroft+I%22">Flitcroft I</searchLink>; Centre for Eye Research Ireland, Technological University Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Loughman+J%22">Loughman J</searchLink>; Optometry School, Technological University Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Mackey+D%22">Mackey D</searchLink>; Lions Eye Institute, University of Western Australia, Perth, Australia.<br /><searchLink fieldCode="AU" term="%22Lee+S%22">Lee S</searchLink>; Lions Eye Institute, University of Western Australia, Perth, Australia.<br /><searchLink fieldCode="AU" term="%22Dahlmann-Noor+A%22">Dahlmann-Noor A</searchLink>; NIHR Moorfields Biomedical Research Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Congdon+N%22">Congdon N</searchLink>; Centre for Public Health, Queen's University Belfast, Belfast, UK.; Orbis International, New York, USA.; Zhongshan Ophthalmic Centre, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Hogg+RE%22">Hogg RE</searchLink>; Centre for Public Health, Queen's University Belfast, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Hammond+CJ%22">Hammond CJ</searchLink>; King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Saunders+K%22">Saunders K</searchLink>; School of Biomedical Sciences, Ulster University, Coleraine, UK.<br /><searchLink fieldCode="AU" term="%22Allen+PM%22">Allen PM</searchLink>; Northern Ireland Clinical Research Facility, Belfast, Ireland, UK.<br /><searchLink fieldCode="AU" term="%22Strang+N%22">Strang N</searchLink>; Department of Vision Sciences, Glasgow Caledonian University, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Clarke+M%22">Clarke M</searchLink>; Centre for Public Health, Queen's University Belfast, Belfast, UK.; Northern Ireland Clinical Trials Unit, Belfast, Ireland, UK.
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  Data: <searchLink fieldCode="JN" term="%228900488%22">BMJ (Clinical research ed.)</searchLink> [BMJ] 2026 Jun 11; Vol. 393, pp. e086698. <i>Date of Electronic Publication: </i>2026 Jun 11.
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        Value: 10.1136/bmj-2025-086698
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