Mes/Stem-A ovarian cancer subtypes predict sensitivity to ATR inhibition.

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Title: Mes/Stem-A ovarian cancer subtypes predict sensitivity to ATR inhibition.
Authors: Sundararajan V; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Ziyu F; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Elfar GA; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tan TZ; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Genomics and Data Analytics Core (GeDaC), Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Kuay KT; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Tan A; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Lai C; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Wengner AM; Bayer AG, Pharmaceuticals, Berlin, Germany.; EPO Berlin-Buch GmbH, Berlin, Germany., Hung HT; Laboratory of Molecular Endocrinology, National Cancer Centre Singapore, Singapore, Singapore., Qi M; Department of Gynecology Oncology, Singapore, Singapore., Chay WY; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore., Cheok CF; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tan DSP; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore. david_sp_tan@nuhs.edu.sg.; Department of Haematology-Oncology, National University Cancer Institute, Singapore, National University Health System Tower Block Level 7, Singapore, Singapore. david_sp_tan@nuhs.edu.sg.
Source: Oncogene [Oncogene] 2026 Jun 11. Date of Electronic Publication: 2026 Jun 11.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Sundararajan+V%22">Sundararajan V</searchLink>; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Ziyu+F%22">Ziyu F</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Elfar+GA%22">Elfar GA</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+TZ%22">Tan TZ</searchLink>; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Genomics and Data Analytics Core (GeDaC), Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Kuay+KT%22">Kuay KT</searchLink>; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+A%22">Tan A</searchLink>; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lai+C%22">Lai C</searchLink>; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Wengner+AM%22">Wengner AM</searchLink>; Bayer AG, Pharmaceuticals, Berlin, Germany.; EPO Berlin-Buch GmbH, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Hung+HT%22">Hung HT</searchLink>; Laboratory of Molecular Endocrinology, National Cancer Centre Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Qi+M%22">Qi M</searchLink>; Department of Gynecology Oncology, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Chay+WY%22">Chay WY</searchLink>; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Cheok+CF%22">Cheok CF</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+DSP%22">Tan DSP</searchLink>; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore. david_sp_tan@nuhs.edu.sg.; Department of Haematology-Oncology, National University Cancer Institute, Singapore, National University Health System Tower Block Level 7, Singapore, Singapore. david_sp_tan@nuhs.edu.sg.
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